10-K Filing

ARROWHEAD PHARMACEUTICALS, INC. CIK: 879407 FY 2021

Filing Information

Form Type	10-K
Accession Number	`0001564590-21-057888`
Period End Date	20210930
Filing Date	20211122
Fiscal Year	2021
Fiscal Period	FY
XBRL Instance	arwr-10k_20210930_htm.xml

Filing Contents

This filing contains the following financial statements:

Balance Sheet 68 Income Statement 50 Cash Flow Statement 69 Stockholders Equity 24

Balance Sheet 68 line items

Line Item	Tag	Value	Unit	Period
Common stock, par value	`CommonStockParOrStatedValuePerShare`	$0.00	USD	Point-in-time
Common stock, par value	`CommonStockParOrStatedValuePerShare`	$0.00	USD	Point-in-time
Common stock, shares authorized	`CommonStockSharesAuthorized`	145.00M	shares	Point-in-time
Common stock, shares authorized	`CommonStockSharesAuthorized`	145.00M	shares	Point-in-time
Cash and cash equivalents	`CashAndCashEquivalentsAtCarryingValue`	$143.58M	USD	Point-in-time
Common stock, shares issued	`CommonStockSharesIssued`	104.33M	shares	Point-in-time
Common stock, shares issued	`CommonStockSharesIssued`	102.38M	shares	Point-in-time
Cash and cash equivalents	`CashAndCashEquivalentsAtCarryingValue`	$184.43M	USD	Point-in-time
Accounts receivable	`AccountsReceivableNetCurrent`	$846.00K	USD	Point-in-time
Common stock, shares outstanding	`CommonStockSharesOutstanding`	102.38M	shares	Point-in-time
Common stock, shares outstanding	`CommonStockSharesOutstanding`	104.33M	shares	Point-in-time
Accounts receivable	`AccountsReceivableNetCurrent`	$10.26M	USD	Point-in-time
Prepaid expenses	`PrepaidExpenseCurrent`	$4.36M	USD	Point-in-time
Prepaid expenses	`PrepaidExpenseCurrent`	$4.25M	USD	Point-in-time
Other current assets	`OtherAssetsCurrent`	$2.19M	USD	Point-in-time
Other current assets	`OtherAssetsCurrent`	$1.78M	USD	Point-in-time
Marketable securities	`MarketableSecuritiesCurrent`	$85.02M	USD	Point-in-time
Marketable securities	`MarketableSecuritiesCurrent`	$126.73M	USD	Point-in-time
Short term investments	`HeldToMaturitySecuritiesCurrent`	$86.89M	USD	Point-in-time
Short term investments	`HeldToMaturitySecuritiesCurrent`	$56.63M	USD	Point-in-time
TOTAL CURRENT ASSETS	`AssetsCurrent`	$384.60M	USD	Point-in-time
TOTAL CURRENT ASSETS	`AssetsCurrent`	$322.37M	USD	Point-in-time
Property and equipment, net	`PropertyPlantAndEquipmentNet`	$30.88M	USD	Point-in-time
Property and equipment, net	`PropertyPlantAndEquipmentNet`	$48.67M	USD	Point-in-time
Intangible assets, net	`FiniteLivedIntangibleAssetsNet`	$15.36M	USD	Point-in-time
Intangible assets, net	`FiniteLivedIntangibleAssetsNet`	$13.66M	USD	Point-in-time
Long term investments	`HeldToMaturitySecuritiesNoncurrent`	$137.49M	USD	Point-in-time
Long term investments	`HeldToMaturitySecuritiesNoncurrent`	$245.59M	USD	Point-in-time
Right-of-use assets	`OperatingLeaseRightOfUseAsset`	$16.14M	USD	Point-in-time
Right-of-use assets	`OperatingLeaseRightOfUseAsset`	$17.35M	USD	Point-in-time
Other assets	`OtherAssetsNoncurrent`	$272.00K	USD	Point-in-time
Other assets	`OtherAssetsNoncurrent`	$264.00K	USD	Point-in-time
TOTAL ASSETS	`Assets`	$710.15M	USD	Point-in-time
TOTAL ASSETS	`Assets`	$522.50M	USD	Point-in-time
Accounts payable	`AccountsPayableCurrent`	$9.46M	USD	Point-in-time
Accounts payable	`AccountsPayableCurrent`	$6.83M	USD	Point-in-time
Accrued expenses	`AccruedLiabilitiesCurrent`	$14.00M	USD	Point-in-time
Accrued expenses	`AccruedLiabilitiesCurrent`	$5.39M	USD	Point-in-time
Accrued payroll and benefits	`EmployeeRelatedLiabilitiesCurrent`	$8.06M	USD	Point-in-time
Accrued payroll and benefits	`EmployeeRelatedLiabilitiesCurrent`	$9.77M	USD	Point-in-time
Lease liabilities	`OperatingLeaseLiabilityCurrent`	$2.25M	USD	Point-in-time
Lease liabilities	`OperatingLeaseLiabilityCurrent`	$1.09M	USD	Point-in-time
Deferred revenue	`ContractWithCustomerLiabilityCurrent`	$111.06M	USD	Point-in-time
Deferred revenue	`ContractWithCustomerLiabilityCurrent`	$19.29M	USD	Point-in-time
Other current liabilities	`OtherLiabilitiesCurrent`	$17.00K	USD	Point-in-time
TOTAL CURRENT LIABILITIES	`LiabilitiesCurrent`	$40.68M	USD	Point-in-time
TOTAL CURRENT LIABILITIES	`LiabilitiesCurrent`	$146.54M	USD	Point-in-time
Lease liabilities, net of current portion	`OperatingLeaseLiabilityNoncurrent`	$20.04M	USD	Point-in-time
Lease liabilities, net of current portion	`OperatingLeaseLiabilityNoncurrent`	$23.30M	USD	Point-in-time
Deferred revenue, net of current portion	`ContractWithCustomerLiabilityNoncurrent`	$131.50M	USD	Point-in-time
TOTAL LONG-TERM LIABILITIES	`LiabilitiesNoncurrent`	$154.79M	USD	Point-in-time
TOTAL LONG-TERM LIABILITIES	`LiabilitiesNoncurrent`	$20.04M	USD	Point-in-time
Commitments and contingencies (Note 7)	`CommitmentsAndContingencies`	-	USD	Point-in-time
Commitments and contingencies (Note 7)	`CommitmentsAndContingencies`	-	USD	Point-in-time
Common stock, $0.001 par value; 145,000 shares authorized; 104,327 and 102,376 shares issued and outstanding as of September 30, 2021 and September 30, 2020, respectively	`CommonStockValue`	$195.00K	USD	Point-in-time
Common stock, $0.001 par value; 145,000 shares authorized; 104,327 and 102,376 shares issued and outstanding as of September 30, 2021 and September 30, 2020, respectively	`CommonStockValue`	$197.00K	USD	Point-in-time
Additional paid-in capital	`AdditionalPaidInCapitalCommonStock`	$1.05B	USD	Point-in-time
Additional paid-in capital	`AdditionalPaidInCapitalCommonStock`	$965.41M	USD	Point-in-time
Accumulated other comprehensive income (loss)	`AccumulatedOtherComprehensiveIncomeLossNetOfTax`	$-69.00K	USD	Point-in-time
Accumulated other comprehensive income (loss)	`AccumulatedOtherComprehensiveIncomeLossNetOfTax`	$18.00K	USD	Point-in-time
Accumulated deficit	`RetainedEarningsAccumulatedDeficit`	$-644.69M	USD	Point-in-time
Accumulated deficit	`RetainedEarningsAccumulatedDeficit`	$-503.84M	USD	Point-in-time
TOTAL STOCKHOLDERS EQUITY	`StockholdersEquityIncludingPortionAttributableToNoncontrollingInterest`	$95.24M	USD	Point-in-time
TOTAL STOCKHOLDERS EQUITY	`StockholdersEquityIncludingPortionAttributableToNoncontrollingInterest`	$461.78M	USD	Point-in-time
TOTAL STOCKHOLDERS EQUITY	`StockholdersEquityIncludingPortionAttributableToNoncontrollingInterest`	$244.04M	USD	Point-in-time
TOTAL STOCKHOLDERS EQUITY	`StockholdersEquityIncludingPortionAttributableToNoncontrollingInterest`	$408.82M	USD	Point-in-time
TOTAL LIABILITIES AND STOCKHOLDERS EQUITY	`LiabilitiesAndStockholdersEquity`	$710.15M	USD	Point-in-time
TOTAL LIABILITIES AND STOCKHOLDERS EQUITY	`LiabilitiesAndStockholdersEquity`	$522.50M	USD	Point-in-time

Income Statement 50 line items

Line Item	Tag	Value	Unit	Period
REVENUE	`RevenueFromContractWithCustomerExcludingAssessedTax`	$138.29M	USD	Annual
REVENUE	`RevenueFromContractWithCustomerExcludingAssessedTax`	$87.99M	USD	Annual
REVENUE	`RevenueFromContractWithCustomerExcludingAssessedTax`	$168.80M	USD	Annual
Research and development	`ResearchAndDevelopmentExpenseExcludingAcquiredInProcessCost`	$206.34M	USD	Annual
Research and development	`ResearchAndDevelopmentExpenseExcludingAcquiredInProcessCost`	$128.88M	USD	Annual
Research and development	`ResearchAndDevelopmentExpenseExcludingAcquiredInProcessCost`	$81.05M	USD	Annual
General and administrative expenses	`GeneralAndAdministrativeExpense`	$80.98M	USD	Annual
General and administrative expenses	`GeneralAndAdministrativeExpense`	$26.56M	USD	Annual
General and administrative expenses	`GeneralAndAdministrativeExpense`	$52.28M	USD	Annual
TOTAL OPERATING EXPENSES	`OperatingExpenses`	$181.15M	USD	Annual
TOTAL OPERATING EXPENSES	`OperatingExpenses`	$107.61M	USD	Annual
TOTAL OPERATING EXPENSES	`OperatingExpenses`	$287.32M	USD	Annual
OPERATING INCOME (LOSS)	`OperatingIncomeLoss`	$61.19M	USD	Annual
OPERATING INCOME (LOSS)	`OperatingIncomeLoss`	$-93.16M	USD	Annual
OPERATING INCOME (LOSS)	`OperatingIncomeLoss`	$-149.04M	USD	Annual
Interest income (expense), net	`InterestIncomeExpenseNonoperatingNet`	$9.19M	USD	Annual
Interest income (expense), net	`InterestIncomeExpenseNonoperatingNet`	$6.12M	USD	Annual
Interest income (expense), net	`InterestIncomeExpenseNonoperatingNet`	$6.96M	USD	Annual
Other income (expense), net	`OtherNonoperatingIncomeExpense`	$2.07M	USD	Annual
Other income (expense), net	`OtherNonoperatingIncomeExpense`	$-583.00K	USD	Annual
TOTAL OTHER INCOME (EXPENSE)	`NonoperatingIncomeExpense`	$8.19M	USD	Annual
TOTAL OTHER INCOME (EXPENSE)	`NonoperatingIncomeExpense`	$6.96M	USD	Annual
TOTAL OTHER INCOME (EXPENSE)	`NonoperatingIncomeExpense`	$8.61M	USD	Annual
INCOME (LOSS) BEFORE INCOME TAXES	`IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest`	$-140.85M	USD	Annual
INCOME (LOSS) BEFORE INCOME TAXES	`IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest`	$68.15M	USD	Annual
INCOME (LOSS) BEFORE INCOME TAXES	`IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest`	$-84.55M	USD	Annual
Provision for income taxes	`IncomeTaxExpenseBenefit`	$2.00K	USD	Annual
Provision for income taxes	`IncomeTaxExpenseBenefit`	$2.00K	USD	Annual
Provision for income taxes	`IncomeTaxExpenseBenefit`	$174.00K	USD	Annual
NET INCOME (LOSS)	`NetIncomeLoss`	$-140.85M	USD	Annual
NET INCOME (LOSS)	`NetIncomeLoss`	$-84.55M	USD	Annual
NET INCOME (LOSS)	`NetIncomeLoss`	$67.97M	USD	Annual
NET INCOME (LOSS) PER SHARE - BASIC	`EarningsPerShareBasic`	$-1.36	USD	Annual
NET INCOME (LOSS) PER SHARE - BASIC	`EarningsPerShareBasic`	$-0.84	USD	Annual
NET INCOME (LOSS) PER SHARE - BASIC	`EarningsPerShareBasic`	$0.72	USD	Annual
NET INCOME (LOSS) PER SHARE - DILUTED	`EarningsPerShareDiluted`	$-1.36	USD	Annual
NET INCOME (LOSS) PER SHARE - DILUTED	`EarningsPerShareDiluted`	$0.69	USD	Annual
NET INCOME (LOSS) PER SHARE - DILUTED	`EarningsPerShareDiluted`	$-0.84	USD	Annual
Weighted average shares outstanding - basic	`WeightedAverageNumberOfSharesOutstandingBasic`	93.86M	shares	Annual
Weighted average shares outstanding - basic	`WeightedAverageNumberOfSharesOutstandingBasic`	103.75M	shares	Annual
Weighted average shares outstanding - basic	`WeightedAverageNumberOfSharesOutstandingBasic`	100.72M	shares	Annual
Weighted average shares outstanding - diluted	`WeightedAverageNumberOfDilutedSharesOutstanding`	100.72M	shares	Annual
Weighted average shares outstanding - diluted	`WeightedAverageNumberOfDilutedSharesOutstanding`	103.75M	shares	Annual
Weighted average shares outstanding - diluted	`WeightedAverageNumberOfDilutedSharesOutstanding`	98.61M	shares	Annual
Foreign currency translation adjustments	`OtherComprehensiveIncomeLossForeignCurrencyTransactionAndTranslationAdjustmentNetOfTax`	$410.00K	USD	Annual
Foreign currency translation adjustments	`OtherComprehensiveIncomeLossForeignCurrencyTransactionAndTranslationAdjustmentNetOfTax`	$-87.00K	USD	Annual
Foreign currency translation adjustments	`OtherComprehensiveIncomeLossForeignCurrencyTransactionAndTranslationAdjustmentNetOfTax`	$-370.00K	USD	Annual
COMPREHENSIVE INCOME (LOSS)	`ComprehensiveIncomeNetOfTax`	$-140.94M	USD	Annual
COMPREHENSIVE INCOME (LOSS)	`ComprehensiveIncomeNetOfTax`	$67.61M	USD	Annual
COMPREHENSIVE INCOME (LOSS)	`ComprehensiveIncomeNetOfTax`	$-84.14M	USD	Annual

Cash Flow Statement 69 line items

Line Item	Tag	Value	Unit	Period
Net income (loss)	`ProfitLoss`	$-140.85M	USD	Annual
Net income (loss)	`ProfitLoss`	$-84.55M	USD	Annual
Net income (loss)	`ProfitLoss`	$67.97M	USD	Annual
Stock-based compensation	`ShareBasedCompensation`	$12.39M	USD	Annual
Stock-based compensation	`ShareBasedCompensation`	$76.67M	USD	Annual
Stock-based compensation	`ShareBasedCompensation`	$43.38M	USD	Annual
Depreciation and amortization	`DepreciationAndAmortization`	$5.94M	USD	Annual
Depreciation and amortization	`DepreciationAndAmortization`	$4.44M	USD	Annual
Depreciation and amortization	`DepreciationAndAmortization`	$8.27M	USD	Annual
Amortization/(accretion) of note premiums	`InvestmentIncomeNetAmortizationOfDiscountAndPremium`	$-266.00K	USD	Annual
Amortization/(accretion) of note premiums	`InvestmentIncomeNetAmortizationOfDiscountAndPremium`	$-525.00K	USD	Annual
Amortization/(accretion) of note premiums	`InvestmentIncomeNetAmortizationOfDiscountAndPremium`	$-1.07M	USD	Annual
Accounts receivable	`IncreaseDecreaseInAccountsReceivable`	$334.00K	USD	Annual
Accounts receivable	`IncreaseDecreaseInAccountsReceivable`	$184.00K	USD	Annual
Accounts receivable	`IncreaseDecreaseInAccountsReceivable`	$9.41M	USD	Annual
Prepaid expenses and other current assets	`IncreaseDecreaseInPrepaidDeferredExpenseAndOtherAssets`	$387.00K	USD	Annual
Prepaid expenses and other current assets	`IncreaseDecreaseInPrepaidDeferredExpenseAndOtherAssets`	$360.00K	USD	Annual
Prepaid expenses and other current assets	`IncreaseDecreaseInPrepaidDeferredExpenseAndOtherAssets`	$3.71M	USD	Annual
Accounts payable	`IncreaseDecreaseInAccountsPayable`	$-821.00K	USD	Annual
Accounts payable	`IncreaseDecreaseInAccountsPayable`	$2.63M	USD	Annual
Accounts payable	`IncreaseDecreaseInAccountsPayable`	$4.84M	USD	Annual
Accrued expenses	`IncreaseDecreaseInAccruedLiabilities`	$9.52M	USD	Annual
Accrued expenses	`IncreaseDecreaseInAccruedLiabilities`	$1.99M	USD	Annual
Accrued expenses	`IncreaseDecreaseInAccruedLiabilities`	$2.45M	USD	Annual
Deferred revenue	`IncreaseDecreaseInContractWithCustomerLiability`	$223.26M	USD	Annual
Deferred revenue	`IncreaseDecreaseInContractWithCustomerLiability`	$-63.51M	USD	Annual
Deferred revenue	`IncreaseDecreaseInContractWithCustomerLiability`	$82.80M	USD	Annual
Other	`IncreaseDecreaseInOtherOperatingLiabilities`	$1.11M	USD	Annual
Other	`IncreaseDecreaseInOtherOperatingLiabilities`	$2.23M	USD	Annual
Other	`IncreaseDecreaseInOtherOperatingLiabilities`	$1.23M	USD	Annual
NET CASH PROVIDED BY (USED IN) OPERATING ACTIVITIES	`NetCashProvidedByUsedInOperatingActivities`	$171.22M	USD	Annual
NET CASH PROVIDED BY (USED IN) OPERATING ACTIVITIES	`NetCashProvidedByUsedInOperatingActivities`	$-95.39M	USD	Annual
NET CASH PROVIDED BY (USED IN) OPERATING ACTIVITIES	`NetCashProvidedByUsedInOperatingActivities`	$173.03M	USD	Annual
Purchases of property and equipment	`PaymentsToAcquirePropertyPlantAndEquipment`	$12.00M	USD	Annual
Purchases of property and equipment	`PaymentsToAcquirePropertyPlantAndEquipment`	$23.57M	USD	Annual
Purchases of property and equipment	`PaymentsToAcquirePropertyPlantAndEquipment`	$11.95M	USD	Annual
Purchases of investments	`PaymentsToAcquireInvestments`	$90.27M	USD	Annual
Purchases of investments	`PaymentsToAcquireInvestments`	$240.70M	USD	Annual
Purchases of investments	`PaymentsToAcquireInvestments`	$278.96M	USD	Annual
Proceeds from sale of investments	`ProceedsFromSaleMaturityAndCollectionsOfInvestments`	$54.52M	USD	Annual
Proceeds from sale of investments	`ProceedsFromSaleMaturityAndCollectionsOfInvestments`	$50.14M	USD	Annual
Proceeds from sale of investments	`ProceedsFromSaleMaturityAndCollectionsOfInvestments`	$122.59M	USD	Annual
NET CASH PROVIDED BY (USED IN) INVESTING ACTIVITIES	`NetCashProvidedByUsedInInvestingActivities`	$-47.75M	USD	Annual
NET CASH PROVIDED BY (USED IN) INVESTING ACTIVITIES	`NetCashProvidedByUsedInInvestingActivities`	$-141.68M	USD	Annual
NET CASH PROVIDED BY (USED IN) INVESTING ACTIVITIES	`NetCashProvidedByUsedInInvestingActivities`	$-240.78M	USD	Annual
Principal payments on notes payable	`RepaymentsOfNotesPayable`	$2.42M	USD	Annual
Proceeds from the exercises of stock options	`ProceedsFromStockOptionsExercised`	$8.28M	USD	Annual
Proceeds from the exercises of stock options	`ProceedsFromStockOptionsExercised`	$11.30M	USD	Annual
Proceeds from the exercises of stock options	`ProceedsFromStockOptionsExercised`	$7.47M	USD	Annual
Proceeds from the issuance of common stock	`ProceedsFromIssuanceOfCommonStock`	$250.48M	USD	Annual
Proceeds from the issuance of common stock	`ProceedsFromIssuanceOfCommonStock`	$60.52M	USD	Annual
NET CASH PROVIDED BY (USED IN) FINANCING ACTIVITIES	`NetCashProvidedByUsedInFinancingActivities`	$11.30M	USD	Annual
NET CASH PROVIDED BY (USED IN) FINANCING ACTIVITIES	`NetCashProvidedByUsedInFinancingActivities`	$257.95M	USD	Annual
NET CASH PROVIDED BY (USED IN) FINANCING ACTIVITIES	`NetCashProvidedByUsedInFinancingActivities`	$66.38M	USD	Annual
NET INCREASE (DECREASE) IN CASH	`CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseIncludingExchangeRateEffect`	$-78.22M	USD	Annual
NET INCREASE (DECREASE) IN CASH	`CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseIncludingExchangeRateEffect`	$40.85M	USD	Annual
NET INCREASE (DECREASE) IN CASH	`CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseIncludingExchangeRateEffect`	$191.67M	USD	Annual
CASH AND CASH EQUIVALENTS AT BEGINNING OF PERIOD	`CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsIncludingDisposalGroupAndDiscontinuedOperations`	$184.43M	USD	Point-in-time
CASH AND CASH EQUIVALENTS AT BEGINNING OF PERIOD	`CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsIncludingDisposalGroupAndDiscontinuedOperations`	$143.58M	USD	Point-in-time
CASH AND CASH EQUIVALENTS AT BEGINNING OF PERIOD	`CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsIncludingDisposalGroupAndDiscontinuedOperations`	$221.80M	USD	Point-in-time
CASH AND CASH EQUIVALENTS AT BEGINNING OF PERIOD	`CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsIncludingDisposalGroupAndDiscontinuedOperations`	$30.13M	USD	Point-in-time
CASH AND CASH EQUIVALENTS AT END OF PERIOD	`CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsIncludingDisposalGroupAndDiscontinuedOperations`	$184.43M	USD	Point-in-time
CASH AND CASH EQUIVALENTS AT END OF PERIOD	`CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsIncludingDisposalGroupAndDiscontinuedOperations`	$143.58M	USD	Point-in-time
CASH AND CASH EQUIVALENTS AT END OF PERIOD	`CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsIncludingDisposalGroupAndDiscontinuedOperations`	$221.80M	USD	Point-in-time
CASH AND CASH EQUIVALENTS AT END OF PERIOD	`CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsIncludingDisposalGroupAndDiscontinuedOperations`	$30.13M	USD	Point-in-time
Interest paid	`InterestPaidNet`	$27.00K	USD	Annual
Income Taxes (Paid)/Refunded	`IncomeTaxesPaidNet`	$-2.00K	USD	Annual
Income Taxes (Paid)/Refunded	`IncomeTaxesPaidNet`	$103.00K	USD	Annual
Income Taxes (Paid)/Refunded	`IncomeTaxesPaidNet`	$-302.00K	USD	Annual

Stockholders Equity 24 line items

Line Item	Tag	Value	Unit	Period
Beginning Balance, Amount	`StockholdersEquityIncludingPortionAttributableToNoncontrollingInterest`	$95.24M	USD	Point-in-time
Beginning Balance, Amount	`StockholdersEquityIncludingPortionAttributableToNoncontrollingInterest`	$461.78M	USD	Point-in-time
Beginning Balance, Amount	`StockholdersEquityIncludingPortionAttributableToNoncontrollingInterest`	$244.04M	USD	Point-in-time
Beginning Balance, Amount	`StockholdersEquityIncludingPortionAttributableToNoncontrollingInterest`	$408.82M	USD	Point-in-time
Stock-based compensation	`AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue`	$12.39M	USD	Annual
Stock-based compensation	`AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue`	$43.38M	USD	Annual
Stock-based compensation	`AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue`	$76.67M	USD	Annual
Exercise of stock options, Amount	`StockIssuedDuringPeriodValueStockOptionsExercised`	$8.28M	USD	Annual
Exercise of stock options, Amount	`StockIssuedDuringPeriodValueStockOptionsExercised`	$7.47M	USD	Annual
Exercise of stock options, Amount	`StockIssuedDuringPeriodValueStockOptionsExercised`	$11.30M	USD	Annual
Exercise of stock options, Shares	`StockIssuedDuringPeriodSharesStockOptionsExercised`	1.05M	shares	Annual
Common stock - issued for cash, Amount	`StockIssuedDuringPeriodValueNewIssues`	$250.48M	USD	Annual
Common stock - issued for cash, Amount	`StockIssuedDuringPeriodValueNewIssues`	$60.52M	USD	Annual
Foreign currency translation adjustments	`OtherComprehensiveIncomeLossForeignCurrencyTransactionAndTranslationAdjustmentNetOfTax`	$410.00K	USD	Annual
Foreign currency translation adjustments	`OtherComprehensiveIncomeLossForeignCurrencyTransactionAndTranslationAdjustmentNetOfTax`	$-87.00K	USD	Annual
Foreign currency translation adjustments	`OtherComprehensiveIncomeLossForeignCurrencyTransactionAndTranslationAdjustmentNetOfTax`	$-370.00K	USD	Annual
Deconsolidation of Ablaris Therapeutics, Inc.	`NoncontrollingInterestDecreaseFromDeconsolidation`	$555.00K	USD	Annual
Net income (loss)	`ProfitLoss`	$-140.85M	USD	Annual
Net income (loss)	`ProfitLoss`	$-84.55M	USD	Annual
Net income (loss)	`ProfitLoss`	$67.97M	USD	Annual
Ending Balance, Amount	`StockholdersEquityIncludingPortionAttributableToNoncontrollingInterest`	$95.24M	USD	Point-in-time
Ending Balance, Amount	`StockholdersEquityIncludingPortionAttributableToNoncontrollingInterest`	$461.78M	USD	Point-in-time
Ending Balance, Amount	`StockholdersEquityIncludingPortionAttributableToNoncontrollingInterest`	$244.04M	USD	Point-in-time
Ending Balance, Amount	`StockholdersEquityIncludingPortionAttributableToNoncontrollingInterest`	$408.82M	USD	Point-in-time

Data is extracted from SEC EDGAR XBRL filings. Values shown are as reported in the filing.