10-K Filing

IOVANCE BIOTHERAPEUTICS, INC. CIK: 1425205 FY 2024

Filing Information

Form Type	10-K
Accession Number	`0001558370-25-001834`
Period End Date	20241231
Filing Date	20250227
Fiscal Year	2024
Fiscal Period	FY
XBRL Instance	iova-20241231x10k_htm.xml

Filing Contents

This filing contains the following financial statements:

Balance Sheet 134 Income Statement 80 Cash Flow Statement 198 Stockholders Equity 64 Comprehensive Income 22

Balance Sheet 134 line items

Line Item	Tag	Value	Unit	Period
Cash and cash equivalents	`CashAndCashEquivalentsAtCarryingValue`	$115.69M	USD	Point-in-time
Cash and cash equivalents	`CashAndCashEquivalentsAtCarryingValue`	$115.69M	USD	Point-in-time
Cash and cash equivalents	`CashAndCashEquivalentsAtCarryingValue`	$231.73M	USD	Point-in-time
Cash and cash equivalents	`CashAndCashEquivalentsAtCarryingValue`	$231.73M	USD	Point-in-time
Cash and cash equivalents	`CashAndCashEquivalentsAtCarryingValue`	$114.89M	USD	Point-in-time
Cash and cash equivalents	`CashAndCashEquivalentsAtCarryingValue`	$114.89M	USD	Point-in-time
Trade accounts receivable	`AccountsReceivableNetCurrent`	$69.34M	USD	Point-in-time
Trade accounts receivable	`AccountsReceivableNetCurrent`	$69.34M	USD	Point-in-time
Trade accounts receivable	`AccountsReceivableNetCurrent`	$151.00K	USD	Point-in-time
Trade accounts receivable	`AccountsReceivableNetCurrent`	$151.00K	USD	Point-in-time
Short-term investments	`ShortTermInvestments`	$208.09M	USD	Point-in-time
Short-term investments	`ShortTermInvestments`	$208.09M	USD	Point-in-time
Common stock, par or stated value per share	`CommonStockParOrStatedValuePerShare`	-	USD	Point-in-time
Common stock, par or stated value per share	`CommonStockParOrStatedValuePerShare`	-	USD	Point-in-time
Common stock, par or stated value per share	`CommonStockParOrStatedValuePerShare`	-	USD	Point-in-time
Common stock, par or stated value per share	`CommonStockParOrStatedValuePerShare`	-	USD	Point-in-time
Short-term investments	`ShortTermInvestments`	$164.98M	USD	Point-in-time
Short-term investments	`ShortTermInvestments`	$164.98M	USD	Point-in-time
Common stock, shares authorized	`CommonStockSharesAuthorized`	500.00M	shares	Point-in-time
Common stock, shares authorized	`CommonStockSharesAuthorized`	500.00M	shares	Point-in-time
Common stock, shares authorized	`CommonStockSharesAuthorized`	500.00M	shares	Point-in-time
Common stock, shares authorized	`CommonStockSharesAuthorized`	500.00M	shares	Point-in-time
Inventory	`InventoryNet`	$51.52M	USD	Point-in-time
Inventory	`InventoryNet`	$51.52M	USD	Point-in-time
Inventory	`InventoryNet`	$10.37M	USD	Point-in-time
Inventory	`InventoryNet`	$10.37M	USD	Point-in-time
Common Stock, Shares, Issued	`CommonStockSharesIssued`	256.14M	shares	Point-in-time
Common Stock, Shares, Issued	`CommonStockSharesIssued`	256.14M	shares	Point-in-time
Prepaid expenses and other assets	`PrepaidExpenseAndOtherAssetsCurrent`	$17.46M	USD	Point-in-time
Prepaid expenses and other assets	`PrepaidExpenseAndOtherAssetsCurrent`	$17.46M	USD	Point-in-time
Common Stock, Shares, Issued	`CommonStockSharesIssued`	305.25M	shares	Point-in-time
Common Stock, Shares, Issued	`CommonStockSharesIssued`	305.25M	shares	Point-in-time
Prepaid expenses and other assets	`PrepaidExpenseAndOtherAssetsCurrent`	$12.38M	USD	Point-in-time
Prepaid expenses and other assets	`PrepaidExpenseAndOtherAssetsCurrent`	$12.38M	USD	Point-in-time
Common Stock, Shares, Outstanding	`CommonStockSharesOutstanding`	305.25M	shares	Point-in-time
Common Stock, Shares, Outstanding	`CommonStockSharesOutstanding`	305.25M	shares	Point-in-time
Common Stock, Shares, Outstanding	`CommonStockSharesOutstanding`	256.14M	shares	Point-in-time
Common Stock, Shares, Outstanding	`CommonStockSharesOutstanding`	256.14M	shares	Point-in-time
Total Current Assets	`AssetsCurrent`	$307.85M	USD	Point-in-time
Total Current Assets	`AssetsCurrent`	$307.85M	USD	Point-in-time
Total Current Assets	`AssetsCurrent`	$457.02M	USD	Point-in-time
Total Current Assets	`AssetsCurrent`	$457.02M	USD	Point-in-time
Property and equipment, net	`PropertyPlantAndEquipmentNet`	$109.08M	USD	Point-in-time
Property and equipment, net	`PropertyPlantAndEquipmentNet`	$109.08M	USD	Point-in-time
Property and equipment, net	`PropertyPlantAndEquipmentNet`	$114.03M	USD	Point-in-time
Property and equipment, net	`PropertyPlantAndEquipmentNet`	$114.03M	USD	Point-in-time
Intangible assets, net	`FiniteLivedIntangibleAssetsNet`	$229.26M	USD	Point-in-time
Intangible assets, net	`FiniteLivedIntangibleAssetsNet`	$229.26M	USD	Point-in-time
Intangible assets, net	`FiniteLivedIntangibleAssetsNet`	$282.40M	USD	Point-in-time
Intangible assets, net	`FiniteLivedIntangibleAssetsNet`	$282.40M	USD	Point-in-time
Operating lease right-of-use assets	`OperatingLeaseRightOfUseAsset`	$62.52M	USD	Point-in-time
Operating lease right-of-use assets	`OperatingLeaseRightOfUseAsset`	$62.52M	USD	Point-in-time
Operating lease right-of-use assets	`OperatingLeaseRightOfUseAsset`	$55.20M	USD	Point-in-time
Operating lease right-of-use assets	`OperatingLeaseRightOfUseAsset`	$55.20M	USD	Point-in-time
Restricted cash	`RestrictedCashNoncurrent`	$6.36M	USD	Point-in-time
Restricted cash	`RestrictedCashNoncurrent`	$6.36M	USD	Point-in-time
Restricted cash	`RestrictedCashNoncurrent`	$66.43M	USD	Point-in-time
Restricted cash	`RestrictedCashNoncurrent`	$66.43M	USD	Point-in-time
Long-term assets	`OtherAssetsNoncurrent`	$270.00K	USD	Point-in-time
Long-term assets	`OtherAssetsNoncurrent`	$270.00K	USD	Point-in-time
Long-term assets	`OtherAssetsNoncurrent`	$369.00K	USD	Point-in-time
Long-term assets	`OtherAssetsNoncurrent`	$369.00K	USD	Point-in-time
Total Assets	`Assets`	$780.35M	USD	Point-in-time
Total Assets	`Assets`	$780.35M	USD	Point-in-time
Total Assets	`Assets`	$910.43M	USD	Point-in-time
Total Assets	`Assets`	$910.43M	USD	Point-in-time
Accounts payable	`AccountsPayableCurrent`	$33.12M	USD	Point-in-time
Accounts payable	`AccountsPayableCurrent`	$33.12M	USD	Point-in-time
Accounts payable	`AccountsPayableCurrent`	$27.51M	USD	Point-in-time
Accounts payable	`AccountsPayableCurrent`	$27.51M	USD	Point-in-time
Accrued expenses and other liabilities	`AccruedLiabilitiesAndOtherLiabilities`	$81.94M	USD	Point-in-time
Accrued expenses and other liabilities	`AccruedLiabilitiesAndOtherLiabilities`	$81.94M	USD	Point-in-time
Accrued expenses and other liabilities	`AccruedLiabilitiesAndOtherLiabilities`	$69.41M	USD	Point-in-time
Accrued expenses and other liabilities	`AccruedLiabilitiesAndOtherLiabilities`	$69.41M	USD	Point-in-time
Operating lease liabilities	`OperatingLeaseLiabilityCurrent`	$12.90M	USD	Point-in-time
Operating lease liabilities	`OperatingLeaseLiabilityCurrent`	$12.90M	USD	Point-in-time
Operating lease liabilities	`OperatingLeaseLiabilityCurrent`	$7.78M	USD	Point-in-time
Operating lease liabilities	`OperatingLeaseLiabilityCurrent`	$7.78M	USD	Point-in-time
Total Current Liabilities	`LiabilitiesCurrent`	$110.31M	USD	Point-in-time
Total Current Liabilities	`LiabilitiesCurrent`	$110.31M	USD	Point-in-time
Total Current Liabilities	`LiabilitiesCurrent`	$122.34M	USD	Point-in-time
Total Current Liabilities	`LiabilitiesCurrent`	$122.34M	USD	Point-in-time
Operating lease liabilities - non-current	`OperatingLeaseLiabilityNoncurrent`	$44.37M	USD	Point-in-time
Operating lease liabilities - non-current	`OperatingLeaseLiabilityNoncurrent`	$44.37M	USD	Point-in-time
Operating lease liabilities - non-current	`OperatingLeaseLiabilityNoncurrent`	$67.08M	USD	Point-in-time
Operating lease liabilities - non-current	`OperatingLeaseLiabilityNoncurrent`	$67.08M	USD	Point-in-time
Deferred tax liabilities	`DeferredIncomeTaxLiabilitiesNet`	$17.35M	USD	Point-in-time
Deferred tax liabilities	`DeferredIncomeTaxLiabilitiesNet`	$17.35M	USD	Point-in-time
Deferred tax liabilities	`DeferredIncomeTaxLiabilitiesNet`	$32.31M	USD	Point-in-time
Deferred tax liabilities	`DeferredIncomeTaxLiabilitiesNet`	$32.31M	USD	Point-in-time
Long-term note payable	`LongTermNotesPayable`	$1.00M	USD	Point-in-time
Long-term note payable	`LongTermNotesPayable`	$1.00M	USD	Point-in-time
Long-term note payable	`LongTermNotesPayable`	$1.00M	USD	Point-in-time
Long-term note payable	`LongTermNotesPayable`	$1.00M	USD	Point-in-time
Total Non-Current Liabilities	`LiabilitiesNoncurrent`	$85.43M	USD	Point-in-time
Total Non-Current Liabilities	`LiabilitiesNoncurrent`	$85.43M	USD	Point-in-time
Total Non-Current Liabilities	`LiabilitiesNoncurrent`	$77.68M	USD	Point-in-time
Total Non-Current Liabilities	`LiabilitiesNoncurrent`	$77.68M	USD	Point-in-time
Total Liabilities	`Liabilities`	$195.74M	USD	Point-in-time
Total Liabilities	`Liabilities`	$195.74M	USD	Point-in-time
Total Liabilities	`Liabilities`	$200.02M	USD	Point-in-time
Total Liabilities	`Liabilities`	$200.02M	USD	Point-in-time
Commitments and contingencies	`CommitmentsAndContingencies`	-	USD	Point-in-time
Commitments and contingencies	`CommitmentsAndContingencies`	-	USD	Point-in-time
Commitments and contingencies	`CommitmentsAndContingencies`	-	USD	Point-in-time
Commitments and contingencies	`CommitmentsAndContingencies`	-	USD	Point-in-time
Common stock, $0.000041666 par value; 500,000,000 shares authorized, 305,252,194 and 256,135,715 shares issued and outstanding as of December 31, 2024 and December 31, 2023, respectively	`CommonStockValue`	$11.00K	USD	Point-in-time
Common stock, $0.000041666 par value; 500,000,000 shares authorized, 305,252,194 and 256,135,715 shares issued and outstanding as of December 31, 2024 and December 31, 2023, respectively	`CommonStockValue`	$11.00K	USD	Point-in-time
Common stock, $0.000041666 par value; 500,000,000 shares authorized, 305,252,194 and 256,135,715 shares issued and outstanding as of December 31, 2024 and December 31, 2023, respectively	`CommonStockValue`	$13.00K	USD	Point-in-time
Common stock, $0.000041666 par value; 500,000,000 shares authorized, 305,252,194 and 256,135,715 shares issued and outstanding as of December 31, 2024 and December 31, 2023, respectively	`CommonStockValue`	$13.00K	USD	Point-in-time
Accumulated other comprehensive loss (income)	`AccumulatedOtherComprehensiveIncomeLossNetOfTax`	$-1.05M	USD	Point-in-time
Accumulated other comprehensive loss (income)	`AccumulatedOtherComprehensiveIncomeLossNetOfTax`	$-1.05M	USD	Point-in-time
Accumulated other comprehensive loss (income)	`AccumulatedOtherComprehensiveIncomeLossNetOfTax`	$2.53M	USD	Point-in-time
Accumulated other comprehensive loss (income)	`AccumulatedOtherComprehensiveIncomeLossNetOfTax`	$2.53M	USD	Point-in-time
Additional paid-in capital	`AdditionalPaidInCapital`	$2.59B	USD	Point-in-time
Additional paid-in capital	`AdditionalPaidInCapital`	$2.59B	USD	Point-in-time
Additional paid-in capital	`AdditionalPaidInCapital`	$3.10B	USD	Point-in-time
Additional paid-in capital	`AdditionalPaidInCapital`	$3.10B	USD	Point-in-time
Accumulated deficit	`RetainedEarningsAccumulatedDeficit`	$-2.01B	USD	Point-in-time
Accumulated deficit	`RetainedEarningsAccumulatedDeficit`	$-2.01B	USD	Point-in-time
Accumulated deficit	`RetainedEarningsAccumulatedDeficit`	$-2.38B	USD	Point-in-time
Accumulated deficit	`RetainedEarningsAccumulatedDeficit`	$-2.38B	USD	Point-in-time
Total Stockholders' Equity	`StockholdersEquity`	$499.64M	USD	Point-in-time
Total Stockholders' Equity	`StockholdersEquity`	$499.64M	USD	Point-in-time
Total Stockholders' Equity	`StockholdersEquity`	$710.40M	USD	Point-in-time
Total Stockholders' Equity	`StockholdersEquity`	$710.40M	USD	Point-in-time
Total Stockholders' Equity	`StockholdersEquity`	$621.66M	USD	Point-in-time
Total Stockholders' Equity	`StockholdersEquity`	$621.66M	USD	Point-in-time
Total Stockholders' Equity	`StockholdersEquity`	$584.61M	USD	Point-in-time
Total Stockholders' Equity	`StockholdersEquity`	$584.61M	USD	Point-in-time
Total Liabilities and Stockholders' Equity	`LiabilitiesAndStockholdersEquity`	$780.35M	USD	Point-in-time
Total Liabilities and Stockholders' Equity	`LiabilitiesAndStockholdersEquity`	$780.35M	USD	Point-in-time
Total Liabilities and Stockholders' Equity	`LiabilitiesAndStockholdersEquity`	$910.43M	USD	Point-in-time
Total Liabilities and Stockholders' Equity	`LiabilitiesAndStockholdersEquity`	$910.43M	USD	Point-in-time

Income Statement 80 line items

Line Item	Tag	Value	Unit	Period
Total net revenue	`RevenueFromContractWithCustomerExcludingAssessedTax`	$1.19M	USD	Annual
Total net revenue	`RevenueFromContractWithCustomerExcludingAssessedTax`	$1.19M	USD	Annual
Total net revenue	`RevenueFromContractWithCustomerExcludingAssessedTax`	$164.07M	USD	Annual
Total net revenue	`RevenueFromContractWithCustomerExcludingAssessedTax`	$164.07M	USD	Annual
Cost of sales	`CostOfRevenue`	$124.00M	USD	Annual
Cost of sales	`CostOfRevenue`	$124.00M	USD	Annual
Cost of sales	`CostOfRevenue`	$10.76M	USD	Annual
Cost of sales	`CostOfRevenue`	$10.76M	USD	Annual
Research and development	`ResearchAndDevelopmentExpense`	$282.34M	USD	Annual
Research and development	`ResearchAndDevelopmentExpense`	$282.34M	USD	Annual
Research and development	`ResearchAndDevelopmentExpense`	$294.78M	USD	Annual
Research and development	`ResearchAndDevelopmentExpense`	$294.78M	USD	Annual
Research and development	`ResearchAndDevelopmentExpense`	$344.08M	USD	Annual
Research and development	`ResearchAndDevelopmentExpense`	$344.08M	USD	Annual
Selling, general and administrative	`GeneralAndAdministrativeExpense`	$153.02M	USD	Annual
Selling, general and administrative	`GeneralAndAdministrativeExpense`	$153.02M	USD	Annual
Selling, general and administrative	`GeneralAndAdministrativeExpense`	$104.10M	USD	Annual
Selling, general and administrative	`GeneralAndAdministrativeExpense`	$104.10M	USD	Annual
Selling, general and administrative	`GeneralAndAdministrativeExpense`	$106.92M	USD	Annual
Selling, general and administrative	`GeneralAndAdministrativeExpense`	$106.92M	USD	Annual
Total costs and expenses	`CostsAndExpenses`	$398.88M	USD	Annual
Total costs and expenses	`CostsAndExpenses`	$398.88M	USD	Annual
Total costs and expenses	`CostsAndExpenses`	$461.75M	USD	Annual
Total costs and expenses	`CostsAndExpenses`	$461.75M	USD	Annual
Total costs and expenses	`CostsAndExpenses`	$559.35M	USD	Annual
Total costs and expenses	`CostsAndExpenses`	$559.35M	USD	Annual
Loss from operations	`OperatingIncomeLoss`	$-460.56M	USD	Annual
Loss from operations	`OperatingIncomeLoss`	$-460.56M	USD	Annual
Loss from operations	`OperatingIncomeLoss`	$-398.88M	USD	Annual
Loss from operations	`OperatingIncomeLoss`	$-398.88M	USD	Annual
Loss from operations	`OperatingIncomeLoss`	$-395.28M	USD	Annual
Loss from operations	`OperatingIncomeLoss`	$-395.28M	USD	Annual
Interest and other income, net	`InvestmentIncomeInterest`	$13.04M	USD	Annual
Interest and other income, net	`InvestmentIncomeInterest`	$13.04M	USD	Annual
Interest and other income, net	`InvestmentIncomeInterest`	$20.27M	USD	Annual
Interest and other income, net	`InvestmentIncomeInterest`	$20.27M	USD	Annual
Interest and other income, net	`InvestmentIncomeInterest`	$2.98M	USD	Annual
Interest and other income, net	`InvestmentIncomeInterest`	$2.98M	USD	Annual
Net Loss before income taxes	`IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest`	$-375.00M	USD	Annual
Net Loss before income taxes	`IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest`	$-375.00M	USD	Annual
Net Loss before income taxes	`IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest`	$-447.52M	USD	Annual
Net Loss before income taxes	`IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest`	$-447.52M	USD	Annual
Net Loss before income taxes	`IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest`	$-395.89M	USD	Annual
Net Loss before income taxes	`IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest`	$-395.89M	USD	Annual
Income tax benefit	`IncomeTaxExpenseBenefit`	$-2.83M	USD	Annual
Income tax benefit	`IncomeTaxExpenseBenefit`	$-2.83M	USD	Annual
Income tax benefit	`IncomeTaxExpenseBenefit`	$-3.48M	USD	Annual
Income tax benefit	`IncomeTaxExpenseBenefit`	$-3.48M	USD	Annual
Income tax benefit	`IncomeTaxExpenseBenefit`	-	USD	Annual
Income tax benefit	`IncomeTaxExpenseBenefit`	-	USD	Annual
Net Loss	`NetIncomeLoss`	$-444.04M	USD	Annual
Net Loss	`NetIncomeLoss`	$-444.04M	USD	Annual
Net Loss	`NetIncomeLoss`	$-395.89M	USD	Annual
Net Loss	`NetIncomeLoss`	$-395.89M	USD	Annual
Net Loss	`NetIncomeLoss`	$-372.18M	USD	Annual
Net Loss	`NetIncomeLoss`	$-372.18M	USD	Annual
Net Loss Per Share of Common Stock, Basic	`EarningsPerShareBasic`	$-1.28	USD	Annual
Net Loss Per Share of Common Stock, Basic	`EarningsPerShareBasic`	$-1.28	USD	Annual
Net Loss Per Share of Common Stock, Basic	`EarningsPerShareBasic`	$-1.89	USD	Annual
Net Loss Per Share of Common Stock, Basic	`EarningsPerShareBasic`	$-1.89	USD	Annual
Net Loss Per Share of Common Stock, Basic	`EarningsPerShareBasic`	$-2.49	USD	Annual
Net Loss Per Share of Common Stock, Basic	`EarningsPerShareBasic`	$-2.49	USD	Annual
Net Loss Per Share of Common Stock, Diluted	`EarningsPerShareDiluted`	$-1.89	USD	Annual
Net Loss Per Share of Common Stock, Diluted	`EarningsPerShareDiluted`	$-1.89	USD	Annual
Net Loss Per Share of Common Stock, Diluted	`EarningsPerShareDiluted`	$-1.28	USD	Annual
Net Loss Per Share of Common Stock, Diluted	`EarningsPerShareDiluted`	$-1.28	USD	Annual
Net Loss Per Share of Common Stock, Diluted	`EarningsPerShareDiluted`	$-2.49	USD	Annual
Net Loss Per Share of Common Stock, Diluted	`EarningsPerShareDiluted`	$-2.49	USD	Annual
Weighted Average Shares of Common Stock Outstanding, Basic	`WeightedAverageNumberOfSharesOutstandingBasic`	235,131.00	shares	Annual
Weighted Average Shares of Common Stock Outstanding, Basic	`WeightedAverageNumberOfSharesOutstandingBasic`	235,131.00	shares	Annual
Weighted Average Shares of Common Stock Outstanding, Basic	`WeightedAverageNumberOfSharesOutstandingBasic`	289,877.00	shares	Annual
Weighted Average Shares of Common Stock Outstanding, Basic	`WeightedAverageNumberOfSharesOutstandingBasic`	289,877.00	shares	Annual
Weighted Average Shares of Common Stock Outstanding, Basic	`WeightedAverageNumberOfSharesOutstandingBasic`	159,259.00	shares	Annual
Weighted Average Shares of Common Stock Outstanding, Basic	`WeightedAverageNumberOfSharesOutstandingBasic`	159,259.00	shares	Annual
Weighted Average Shares of Common Stock Outstanding, Diluted	`WeightedAverageNumberOfDilutedSharesOutstanding`	289,877.00	shares	Annual
Weighted Average Shares of Common Stock Outstanding, Diluted	`WeightedAverageNumberOfDilutedSharesOutstanding`	289,877.00	shares	Annual
Weighted Average Shares of Common Stock Outstanding, Diluted	`WeightedAverageNumberOfDilutedSharesOutstanding`	159,259.00	shares	Annual
Weighted Average Shares of Common Stock Outstanding, Diluted	`WeightedAverageNumberOfDilutedSharesOutstanding`	159,259.00	shares	Annual
Weighted Average Shares of Common Stock Outstanding, Diluted	`WeightedAverageNumberOfDilutedSharesOutstanding`	235,131.00	shares	Annual
Weighted Average Shares of Common Stock Outstanding, Diluted	`WeightedAverageNumberOfDilutedSharesOutstanding`	235,131.00	shares	Annual

Cash Flow Statement 198 line items

Line Item	Tag	Value	Unit	Period
Net Income (Loss)	`NetIncomeLoss`	$-444.04M	USD	Annual
Net Income (Loss)	`NetIncomeLoss`	$-444.04M	USD	Annual
Net Income (Loss)	`NetIncomeLoss`	$-395.89M	USD	Annual
Net Income (Loss)	`NetIncomeLoss`	$-395.89M	USD	Annual
Net Income (Loss)	`NetIncomeLoss`	$-372.18M	USD	Annual
Net Income (Loss)	`NetIncomeLoss`	$-372.18M	USD	Annual
Stock-based compensation expense	`ShareBasedCompensation`	$109.63M	USD	Annual
Stock-based compensation expense	`ShareBasedCompensation`	$109.63M	USD	Annual
Stock-based compensation expense	`ShareBasedCompensation`	$84.02M	USD	Annual
Stock-based compensation expense	`ShareBasedCompensation`	$84.02M	USD	Annual
Stock-based compensation expense	`ShareBasedCompensation`	$62.62M	USD	Annual
Stock-based compensation expense	`ShareBasedCompensation`	$62.62M	USD	Annual
Unrealized foreign exchange gains	`ForeignCurrencyTransactionGainLossBeforeTax`	$-70.00K	USD	Annual
Unrealized foreign exchange gains	`ForeignCurrencyTransactionGainLossBeforeTax`	$-70.00K	USD	Annual
Unrealized foreign exchange gains	`ForeignCurrencyTransactionGainLossBeforeTax`	$175.00K	USD	Annual
Unrealized foreign exchange gains	`ForeignCurrencyTransactionGainLossBeforeTax`	$175.00K	USD	Annual
Amortization of intangible assets	`AmortizationOfIntangibleAssets`	$21.20M	USD	Annual
Amortization of intangible assets	`AmortizationOfIntangibleAssets`	$21.20M	USD	Annual
Amortization of intangible assets	`AmortizationOfIntangibleAssets`	$9.85M	USD	Annual
Amortization of intangible assets	`AmortizationOfIntangibleAssets`	$9.85M	USD	Annual
Amortization of right of use asset	`OperatingLeaseRightOfUseAssetAmortizationExpense`	$11.82M	USD	Annual
Amortization of right of use asset	`OperatingLeaseRightOfUseAssetAmortizationExpense`	$11.82M	USD	Annual
Amortization of right of use asset	`OperatingLeaseRightOfUseAssetAmortizationExpense`	$10.44M	USD	Annual
Amortization of right of use asset	`OperatingLeaseRightOfUseAssetAmortizationExpense`	$10.44M	USD	Annual
Amortization of right of use asset	`OperatingLeaseRightOfUseAssetAmortizationExpense`	$11.71M	USD	Annual
Amortization of right of use asset	`OperatingLeaseRightOfUseAssetAmortizationExpense`	$11.71M	USD	Annual
Depreciation and amortization of property and equipment	`DepreciationDepletionAndAmortization`	$9.31M	USD	Annual
Depreciation and amortization of property and equipment	`DepreciationDepletionAndAmortization`	$9.31M	USD	Annual
Depreciation and amortization of property and equipment	`DepreciationDepletionAndAmortization`	$11.57M	USD	Annual
Depreciation and amortization of property and equipment	`DepreciationDepletionAndAmortization`	$11.57M	USD	Annual
Depreciation and amortization of property and equipment	`DepreciationDepletionAndAmortization`	$11.97M	USD	Annual
Depreciation and amortization of property and equipment	`DepreciationDepletionAndAmortization`	$11.97M	USD	Annual
Deferred tax benefit	`DeferredIncomeTaxExpenseBenefit`	$-2.83M	USD	Annual
Deferred tax benefit	`DeferredIncomeTaxExpenseBenefit`	$-2.83M	USD	Annual
Deferred tax benefit	`DeferredIncomeTaxExpenseBenefit`	$-3.48M	USD	Annual
Deferred tax benefit	`DeferredIncomeTaxExpenseBenefit`	$-3.48M	USD	Annual
Accretion of discounts and premiums on investments	`AccretionAmortizationOfDiscountsAndPremiumsInvestments`	$-474.00K	USD	Annual
Accretion of discounts and premiums on investments	`AccretionAmortizationOfDiscountsAndPremiumsInvestments`	$-474.00K	USD	Annual
Accretion of discounts and premiums on investments	`AccretionAmortizationOfDiscountsAndPremiumsInvestments`	$3.60M	USD	Annual
Accretion of discounts and premiums on investments	`AccretionAmortizationOfDiscountsAndPremiumsInvestments`	$3.60M	USD	Annual
Accretion of discounts and premiums on investments	`AccretionAmortizationOfDiscountsAndPremiumsInvestments`	$10.26M	USD	Annual
Accretion of discounts and premiums on investments	`AccretionAmortizationOfDiscountsAndPremiumsInvestments`	$10.26M	USD	Annual
Impairment of long-lived assets	`ImpairmentOfLongLivedAssetsHeldForUse`	$397.00K	USD	Annual
Impairment of long-lived assets	`ImpairmentOfLongLivedAssetsHeldForUse`	$397.00K	USD	Annual
Impairment of long-lived assets	`ImpairmentOfLongLivedAssetsHeldForUse`	$7.36M	USD	Annual
Impairment of long-lived assets	`ImpairmentOfLongLivedAssetsHeldForUse`	$7.36M	USD	Annual
Gain on derecognition of lease assets and liabilities	`GainLossOnTerminationOfLease`	$5.57M	USD	Annual
Gain on derecognition of lease assets and liabilities	`GainLossOnTerminationOfLease`	$5.57M	USD	Annual
Prepaid expenses, other assets and long-term assets	`IncreaseDecreaseInPrepaidDeferredExpenseAndOtherAssets`	$2.13M	USD	Annual
Prepaid expenses, other assets and long-term assets	`IncreaseDecreaseInPrepaidDeferredExpenseAndOtherAssets`	$2.13M	USD	Annual
Prepaid expenses, other assets and long-term assets	`IncreaseDecreaseInPrepaidDeferredExpenseAndOtherAssets`	$2.11M	USD	Annual
Prepaid expenses, other assets and long-term assets	`IncreaseDecreaseInPrepaidDeferredExpenseAndOtherAssets`	$2.11M	USD	Annual
Prepaid expenses, other assets and long-term assets	`IncreaseDecreaseInPrepaidDeferredExpenseAndOtherAssets`	$10.06M	USD	Annual
Prepaid expenses, other assets and long-term assets	`IncreaseDecreaseInPrepaidDeferredExpenseAndOtherAssets`	$10.06M	USD	Annual
Trade accounts receivable	`IncreaseDecreaseInAccountsReceivable`	$149.00K	USD	Annual
Trade accounts receivable	`IncreaseDecreaseInAccountsReceivable`	$149.00K	USD	Annual
Trade accounts receivable	`IncreaseDecreaseInAccountsReceivable`	$69.19M	USD	Annual
Trade accounts receivable	`IncreaseDecreaseInAccountsReceivable`	$69.19M	USD	Annual
Inventory	`IncreaseDecreaseInInventories`	$39.92M	USD	Annual
Inventory	`IncreaseDecreaseInInventories`	$39.92M	USD	Annual
Inventory	`IncreaseDecreaseInInventories`	$10.12M	USD	Annual
Inventory	`IncreaseDecreaseInInventories`	$10.12M	USD	Annual
Operating lease liabilities	`IncreaseDecreaseInOperatingLeaseLiability`	$-10.79M	USD	Annual
Operating lease liabilities	`IncreaseDecreaseInOperatingLeaseLiability`	$-10.79M	USD	Annual
Operating lease liabilities	`IncreaseDecreaseInOperatingLeaseLiability`	$-12.07M	USD	Annual
Operating lease liabilities	`IncreaseDecreaseInOperatingLeaseLiability`	$-12.07M	USD	Annual
Operating lease liabilities	`IncreaseDecreaseInOperatingLeaseLiability`	$-1.94M	USD	Annual
Operating lease liabilities	`IncreaseDecreaseInOperatingLeaseLiability`	$-1.94M	USD	Annual
Accounts payable	`IncreaseDecreaseInAccountsPayable`	$-7.84M	USD	Annual
Accounts payable	`IncreaseDecreaseInAccountsPayable`	$-7.84M	USD	Annual
Accounts payable	`IncreaseDecreaseInAccountsPayable`	$5.88M	USD	Annual
Accounts payable	`IncreaseDecreaseInAccountsPayable`	$5.88M	USD	Annual
Accounts payable	`IncreaseDecreaseInAccountsPayable`	$4.83M	USD	Annual
Accounts payable	`IncreaseDecreaseInAccountsPayable`	$4.83M	USD	Annual
Accrued expenses and other liabilities	`IncreaseDecreaseInAccruedLiabilities`	$-4.70M	USD	Annual
Accrued expenses and other liabilities	`IncreaseDecreaseInAccruedLiabilities`	$-4.70M	USD	Annual
Accrued expenses and other liabilities	`IncreaseDecreaseInAccruedLiabilities`	$8.58M	USD	Annual
Accrued expenses and other liabilities	`IncreaseDecreaseInAccruedLiabilities`	$8.58M	USD	Annual
Accrued expenses and other liabilities	`IncreaseDecreaseInAccruedLiabilities`	$19.77M	USD	Annual
Accrued expenses and other liabilities	`IncreaseDecreaseInAccruedLiabilities`	$19.77M	USD	Annual
Net cash used in operating activities	`NetCashProvidedByUsedInOperatingActivities`	$-361.82M	USD	Annual
Net cash used in operating activities	`NetCashProvidedByUsedInOperatingActivities`	$-361.82M	USD	Annual
Net cash used in operating activities	`NetCashProvidedByUsedInOperatingActivities`	$-352.98M	USD	Annual
Net cash used in operating activities	`NetCashProvidedByUsedInOperatingActivities`	$-352.98M	USD	Annual
Net cash used in operating activities	`NetCashProvidedByUsedInOperatingActivities`	$-292.76M	USD	Annual
Net cash used in operating activities	`NetCashProvidedByUsedInOperatingActivities`	$-292.76M	USD	Annual
Maturities of investments	`ProceedsFromSaleAndMaturityOfAvailableForSaleSecurities`	$522.70M	USD	Annual
Maturities of investments	`ProceedsFromSaleAndMaturityOfAvailableForSaleSecurities`	$522.70M	USD	Annual
Maturities of investments	`ProceedsFromSaleAndMaturityOfAvailableForSaleSecurities`	$428.00M	USD	Annual
Maturities of investments	`ProceedsFromSaleAndMaturityOfAvailableForSaleSecurities`	$428.00M	USD	Annual
Maturities of investments	`ProceedsFromSaleAndMaturityOfAvailableForSaleSecurities`	$285.58M	USD	Annual
Maturities of investments	`ProceedsFromSaleAndMaturityOfAvailableForSaleSecurities`	$285.58M	USD	Annual
Purchase of investments	`PaymentsToAcquireAvailableForSaleSecuritiesDebt`	$245.82M	USD	Annual
Purchase of investments	`PaymentsToAcquireAvailableForSaleSecuritiesDebt`	$245.82M	USD	Annual
Purchase of investments	`PaymentsToAcquireAvailableForSaleSecuritiesDebt`	$205.90M	USD	Annual
Purchase of investments	`PaymentsToAcquireAvailableForSaleSecuritiesDebt`	$205.90M	USD	Annual
Purchase of investments	`PaymentsToAcquireAvailableForSaleSecuritiesDebt`	$460.77M	USD	Annual
Purchase of investments	`PaymentsToAcquireAvailableForSaleSecuritiesDebt`	$460.77M	USD	Annual
Cash paid for acquisition, including contingent consideration, net of cash acquired	`PaymentsForAssetAcquisitionIncludingContingentConsiderationNetOfCashAcquired`	$212.63M	USD	Annual
Cash paid for acquisition, including contingent consideration, net of cash acquired	`PaymentsForAssetAcquisitionIncludingContingentConsiderationNetOfCashAcquired`	$212.63M	USD	Annual
Cash paid for acquisition, including contingent consideration, net of cash acquired	`PaymentsForAssetAcquisitionIncludingContingentConsiderationNetOfCashAcquired`	$52.57M	USD	Annual
Cash paid for acquisition, including contingent consideration, net of cash acquired	`PaymentsForAssetAcquisitionIncludingContingentConsiderationNetOfCashAcquired`	$52.57M	USD	Annual
Purchase of property and equipment	`PaymentsToAcquirePropertyPlantAndEquipment`	$22.29M	USD	Annual
Purchase of property and equipment	`PaymentsToAcquirePropertyPlantAndEquipment`	$22.29M	USD	Annual
Purchase of property and equipment	`PaymentsToAcquirePropertyPlantAndEquipment`	$11.07M	USD	Annual
Purchase of property and equipment	`PaymentsToAcquirePropertyPlantAndEquipment`	$11.07M	USD	Annual
Purchase of property and equipment	`PaymentsToAcquirePropertyPlantAndEquipment`	$20.43M	USD	Annual
Purchase of property and equipment	`PaymentsToAcquirePropertyPlantAndEquipment`	$20.43M	USD	Annual
Net cash used in investing activities	`NetCashProvidedByUsedInInvestingActivities`	$-155.24M	USD	Annual
Net cash used in investing activities	`NetCashProvidedByUsedInInvestingActivities`	$-155.24M	USD	Annual
Net cash used in investing activities	`NetCashProvidedByUsedInInvestingActivities`	$256.45M	USD	Annual
Net cash used in investing activities	`NetCashProvidedByUsedInInvestingActivities`	$256.45M	USD	Annual
Net cash used in investing activities	`NetCashProvidedByUsedInInvestingActivities`	$-96.41M	USD	Annual
Net cash used in investing activities	`NetCashProvidedByUsedInInvestingActivities`	$-96.41M	USD	Annual
Tax payments related to shares withheld for vested restricted stock units	`PaymentsRelatedToTaxWithholdingForShareBasedCompensation`	$2.65M	USD	Annual
Tax payments related to shares withheld for vested restricted stock units	`PaymentsRelatedToTaxWithholdingForShareBasedCompensation`	$2.65M	USD	Annual
Tax payments related to shares withheld for vested restricted stock units	`PaymentsRelatedToTaxWithholdingForShareBasedCompensation`	$12.86M	USD	Annual
Tax payments related to shares withheld for vested restricted stock units	`PaymentsRelatedToTaxWithholdingForShareBasedCompensation`	$12.86M	USD	Annual
Tax payments related to shares withheld for vested restricted stock units	`PaymentsRelatedToTaxWithholdingForShareBasedCompensation`	$2.79M	USD	Annual
Tax payments related to shares withheld for vested restricted stock units	`PaymentsRelatedToTaxWithholdingForShareBasedCompensation`	$2.79M	USD	Annual
Proceeds from the issuance of common stock under employee stock purchase plan	`ProceedsFromIssuanceOfCommonStockUnderEmployeeStockPurchasePlan`	$2.95M	USD	Annual
Proceeds from the issuance of common stock under employee stock purchase plan	`ProceedsFromIssuanceOfCommonStockUnderEmployeeStockPurchasePlan`	$2.95M	USD	Annual
Proceeds from the issuance of common stock under employee stock purchase plan	`ProceedsFromIssuanceOfCommonStockUnderEmployeeStockPurchasePlan`	$1.66M	USD	Annual
Proceeds from the issuance of common stock under employee stock purchase plan	`ProceedsFromIssuanceOfCommonStockUnderEmployeeStockPurchasePlan`	$1.66M	USD	Annual
Proceeds from the issuance of common stock under employee stock purchase plan	`ProceedsFromIssuanceOfCommonStockUnderEmployeeStockPurchasePlan`	$2.41M	USD	Annual
Proceeds from the issuance of common stock under employee stock purchase plan	`ProceedsFromIssuanceOfCommonStockUnderEmployeeStockPurchasePlan`	$2.41M	USD	Annual
Proceeds from the issuance of common stock upon exercise of options	`ProceedsFromStockOptionsExercised`	$1.64M	USD	Annual
Proceeds from the issuance of common stock upon exercise of options	`ProceedsFromStockOptionsExercised`	$1.64M	USD	Annual
Proceeds from the issuance of common stock upon exercise of options	`ProceedsFromStockOptionsExercised`	$63.00K	USD	Annual
Proceeds from the issuance of common stock upon exercise of options	`ProceedsFromStockOptionsExercised`	$63.00K	USD	Annual
Proceeds from the issuance of common stock upon exercise of options	`ProceedsFromStockOptionsExercised`	$3.27M	USD	Annual
Proceeds from the issuance of common stock upon exercise of options	`ProceedsFromStockOptionsExercised`	$3.27M	USD	Annual
Proceeds from the issuance of common stock, net	`ProceedsFromIssuanceOfCommonStock`	$397.30M	USD	Annual
Proceeds from the issuance of common stock, net	`ProceedsFromIssuanceOfCommonStock`	$397.30M	USD	Annual
Proceeds from the issuance of common stock, net	`ProceedsFromIssuanceOfCommonStock`	$189.50M	USD	Annual
Proceeds from the issuance of common stock, net	`ProceedsFromIssuanceOfCommonStock`	$189.50M	USD	Annual
Proceeds from the issuance of common stock, net	`ProceedsFromIssuanceOfCommonStock`	$463.28M	USD	Annual
Proceeds from the issuance of common stock, net	`ProceedsFromIssuanceOfCommonStock`	$463.28M	USD	Annual
Net cash provided by financing activities	`NetCashProvidedByUsedInFinancingActivities`	$462.96M	USD	Annual
Net cash provided by financing activities	`NetCashProvidedByUsedInFinancingActivities`	$462.96M	USD	Annual
Net cash provided by financing activities	`NetCashProvidedByUsedInFinancingActivities`	$190.15M	USD	Annual
Net cash provided by financing activities	`NetCashProvidedByUsedInFinancingActivities`	$190.15M	USD	Annual
Net cash provided by financing activities	`NetCashProvidedByUsedInFinancingActivities`	$390.66M	USD	Annual
Net cash provided by financing activities	`NetCashProvidedByUsedInFinancingActivities`	$390.66M	USD	Annual
Effect of foreign exchange rate changes	`EffectOfExchangeRateOnCashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents`	$-2.74M	USD	Annual
Effect of foreign exchange rate changes	`EffectOfExchangeRateOnCashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents`	$-2.74M	USD	Annual
Effect of foreign exchange rate changes	`EffectOfExchangeRateOnCashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents`	$-541.00K	USD	Annual
Effect of foreign exchange rate changes	`EffectOfExchangeRateOnCashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents`	$-541.00K	USD	Annual
Net increase in cash, cash equivalents and restricted cash	`CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseIncludingExchangeRateEffect`	$153.85M	USD	Annual
Net increase in cash, cash equivalents and restricted cash	`CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseIncludingExchangeRateEffect`	$153.85M	USD	Annual
Net increase in cash, cash equivalents and restricted cash	`CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseIncludingExchangeRateEffect`	$-56.84M	USD	Annual
Net increase in cash, cash equivalents and restricted cash	`CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseIncludingExchangeRateEffect`	$-56.84M	USD	Annual
Net increase in cash, cash equivalents and restricted cash	`CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseIncludingExchangeRateEffect`	$-59.27M	USD	Annual
Net increase in cash, cash equivalents and restricted cash	`CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseIncludingExchangeRateEffect`	$-59.27M	USD	Annual
Cash, Cash Equivalents and Restricted Cash Beginning of Period	`CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents`	$122.05M	USD	Point-in-time
Cash, Cash Equivalents and Restricted Cash Beginning of Period	`CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents`	$122.05M	USD	Point-in-time
Cash, Cash Equivalents and Restricted Cash Beginning of Period	`CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents`	$181.32M	USD	Point-in-time
Cash, Cash Equivalents and Restricted Cash Beginning of Period	`CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents`	$181.32M	USD	Point-in-time
Cash, Cash Equivalents and Restricted Cash Beginning of Period	`CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents`	$238.16M	USD	Point-in-time
Cash, Cash Equivalents and Restricted Cash Beginning of Period	`CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents`	$238.16M	USD	Point-in-time
Cash, Cash Equivalents and Restricted Cash Beginning of Period	`CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents`	$84.31M	USD	Point-in-time
Cash, Cash Equivalents and Restricted Cash Beginning of Period	`CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents`	$84.31M	USD	Point-in-time
Cash, Cash Equivalents and Restricted Cash End of Period	`CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents`	$122.05M	USD	Point-in-time
Cash, Cash Equivalents and Restricted Cash End of Period	`CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents`	$122.05M	USD	Point-in-time
Cash, Cash Equivalents and Restricted Cash End of Period	`CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents`	$181.32M	USD	Point-in-time
Cash, Cash Equivalents and Restricted Cash End of Period	`CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents`	$181.32M	USD	Point-in-time
Cash, Cash Equivalents and Restricted Cash End of Period	`CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents`	$238.16M	USD	Point-in-time
Cash, Cash Equivalents and Restricted Cash End of Period	`CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents`	$238.16M	USD	Point-in-time
Cash, Cash Equivalents and Restricted Cash End of Period	`CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents`	$84.31M	USD	Point-in-time
Cash, Cash Equivalents and Restricted Cash End of Period	`CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents`	$84.31M	USD	Point-in-time
Fair value of net assets acquired	`FairValueOfAssetsAcquired`	$222.64M	USD	Annual
Fair value of net assets acquired	`FairValueOfAssetsAcquired`	$222.64M	USD	Annual
Net unrealized gain on investments	`UnrealizedGainLossOnInvestments`	$-301.00K	USD	Annual
Net unrealized gain on investments	`UnrealizedGainLossOnInvestments`	$-301.00K	USD	Annual
Net unrealized gain on investments	`UnrealizedGainLossOnInvestments`	$78.00K	USD	Annual
Net unrealized gain on investments	`UnrealizedGainLossOnInvestments`	$78.00K	USD	Annual
Net unrealized gain on investments	`UnrealizedGainLossOnInvestments`	$940.00K	USD	Annual
Net unrealized gain on investments	`UnrealizedGainLossOnInvestments`	$940.00K	USD	Annual
Acquisition of property and equipment included in accounts payable and accrued expenses	`AcquisitionsOfPropertyAndEquipmentIncludedInAccountsPayableAndAccruedExpense`	$-7.37M	USD	Annual
Acquisition of property and equipment included in accounts payable and accrued expenses	`AcquisitionsOfPropertyAndEquipmentIncludedInAccountsPayableAndAccruedExpense`	$-7.37M	USD	Annual
Acquisition of property and equipment included in accounts payable and accrued expenses	`AcquisitionsOfPropertyAndEquipmentIncludedInAccountsPayableAndAccruedExpense`	$-4.06M	USD	Annual
Acquisition of property and equipment included in accounts payable and accrued expenses	`AcquisitionsOfPropertyAndEquipmentIncludedInAccountsPayableAndAccruedExpense`	$-4.06M	USD	Annual
Acquisition of property and equipment included in accounts payable and accrued expenses	`AcquisitionsOfPropertyAndEquipmentIncludedInAccountsPayableAndAccruedExpense`	$-5.99M	USD	Annual
Acquisition of property and equipment included in accounts payable and accrued expenses	`AcquisitionsOfPropertyAndEquipmentIncludedInAccountsPayableAndAccruedExpense`	$-5.99M	USD	Annual
Intangible asset and deferred tax liability arising from contingent consideration	`NoncashOrPartNoncashAcquisitionIntangibleAssetsAcquired1`	$17.50M	USD	Annual
Intangible asset and deferred tax liability arising from contingent consideration	`NoncashOrPartNoncashAcquisitionIntangibleAssetsAcquired1`	$17.50M	USD	Annual
Lease liabilities arising from obtaining right-of-use asset from new leases	`Rightofuseassetobtainedinexchangeforoperatingleaseliabilityfromnewleases`	$553.00K	USD	Annual
Lease liabilities arising from obtaining right-of-use asset from new leases	`Rightofuseassetobtainedinexchangeforoperatingleaseliabilityfromnewleases`	$553.00K	USD	Annual
Lease liabilities arising from obtaining right-of-use asset from new leases	`Rightofuseassetobtainedinexchangeforoperatingleaseliabilityfromnewleases`	$177.00K	USD	Annual
Lease liabilities arising from obtaining right-of-use asset from new leases	`Rightofuseassetobtainedinexchangeforoperatingleaseliabilityfromnewleases`	$177.00K	USD	Annual
Lease liabilities arising from obtaining right-of-use asset from new leases	`Rightofuseassetobtainedinexchangeforoperatingleaseliabilityfromnewleases`	$2.31M	USD	Annual
Lease liabilities arising from obtaining right-of-use asset from new leases	`Rightofuseassetobtainedinexchangeforoperatingleaseliabilityfromnewleases`	$2.31M	USD	Annual
Lease liabilities arising from obtaining right-of-use asset from lease modifications	`RightOfUseAssetObtainedInExchangeForOperatingLeaseLiabilityFromLeaseModifications`	$-7.83M	USD	Annual
Lease liabilities arising from obtaining right-of-use asset from lease modifications	`RightOfUseAssetObtainedInExchangeForOperatingLeaseLiabilityFromLeaseModifications`	$-7.83M	USD	Annual
Lease liabilities arising from obtaining right-of-use asset from lease modifications	`RightOfUseAssetObtainedInExchangeForOperatingLeaseLiabilityFromLeaseModifications`	$15.30M	USD	Annual
Lease liabilities arising from obtaining right-of-use asset from lease modifications	`RightOfUseAssetObtainedInExchangeForOperatingLeaseLiabilityFromLeaseModifications`	$15.30M	USD	Annual
Lease liabilities arising from obtaining right-of-use asset from lease modifications	`RightOfUseAssetObtainedInExchangeForOperatingLeaseLiabilityFromLeaseModifications`	$1.03M	USD	Annual
Lease liabilities arising from obtaining right-of-use asset from lease modifications	`RightOfUseAssetObtainedInExchangeForOperatingLeaseLiabilityFromLeaseModifications`	$1.03M	USD	Annual

Stockholders Equity 64 line items

Line Item	Tag	Value	Unit	Period
Beginning Balance	`StockholdersEquity`	$499.64M	USD	Point-in-time
Beginning Balance	`StockholdersEquity`	$499.64M	USD	Point-in-time
Beginning Balance	`StockholdersEquity`	$710.40M	USD	Point-in-time
Beginning Balance	`StockholdersEquity`	$710.40M	USD	Point-in-time
Beginning Balance	`StockholdersEquity`	$621.66M	USD	Point-in-time
Beginning Balance	`StockholdersEquity`	$621.66M	USD	Point-in-time
Beginning Balance	`StockholdersEquity`	$584.61M	USD	Point-in-time
Beginning Balance	`StockholdersEquity`	$584.61M	USD	Point-in-time
Stock-based compensation expense	`AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue`	$110.88M	USD	Annual
Stock-based compensation expense	`AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue`	$110.88M	USD	Annual
Stock-based compensation expense	`AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue`	$84.02M	USD	Annual
Stock-based compensation expense	`AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue`	$84.02M	USD	Annual
Stock-based compensation expense	`AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue`	$62.62M	USD	Annual
Stock-based compensation expense	`AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue`	$62.62M	USD	Annual
Common stock issued upon purchase of employee stock purchase plan	`StockIssuedDuringPeriodValueEmployeeStockPurchasePlan`	$2.95M	USD	Annual
Common stock issued upon purchase of employee stock purchase plan	`StockIssuedDuringPeriodValueEmployeeStockPurchasePlan`	$2.95M	USD	Annual
Common stock issued upon purchase of employee stock purchase plan	`StockIssuedDuringPeriodValueEmployeeStockPurchasePlan`	$1.66M	USD	Annual
Common stock issued upon purchase of employee stock purchase plan	`StockIssuedDuringPeriodValueEmployeeStockPurchasePlan`	$1.66M	USD	Annual
Common stock issued upon purchase of employee stock purchase plan	`StockIssuedDuringPeriodValueEmployeeStockPurchasePlan`	$2.41M	USD	Annual
Common stock issued upon purchase of employee stock purchase plan	`StockIssuedDuringPeriodValueEmployeeStockPurchasePlan`	$2.41M	USD	Annual
Tax payments related to shares retired for vested restricted stock units	`AdjustmentToAdditionalPaidInCapitalIncomeTaxEffectFromShareBasedCompensationsNet`	$-2.79M	USD	Annual
Tax payments related to shares retired for vested restricted stock units	`AdjustmentToAdditionalPaidInCapitalIncomeTaxEffectFromShareBasedCompensationsNet`	$-2.79M	USD	Annual
Tax payments related to shares retired for vested restricted stock units	`AdjustmentToAdditionalPaidInCapitalIncomeTaxEffectFromShareBasedCompensationsNet`	$-2.65M	USD	Annual
Tax payments related to shares retired for vested restricted stock units	`AdjustmentToAdditionalPaidInCapitalIncomeTaxEffectFromShareBasedCompensationsNet`	$-2.65M	USD	Annual
Tax payments related to shares retired for vested restricted stock units	`AdjustmentToAdditionalPaidInCapitalIncomeTaxEffectFromShareBasedCompensationsNet`	$-12.86M	USD	Annual
Tax payments related to shares retired for vested restricted stock units	`AdjustmentToAdditionalPaidInCapitalIncomeTaxEffectFromShareBasedCompensationsNet`	$-12.86M	USD	Annual
Common stock sold in public and/or at the market offering, net of offering costs	`StockIssuedDuringPeriodValueOther`	$189.50M	USD	Annual
Common stock sold in public and/or at the market offering, net of offering costs	`StockIssuedDuringPeriodValueOther`	$189.50M	USD	Annual
Common stock sold in public and/or at the market offering, net of offering costs	`StockIssuedDuringPeriodValueOther`	$397.30M	USD	Annual
Common stock sold in public and/or at the market offering, net of offering costs	`StockIssuedDuringPeriodValueOther`	$397.30M	USD	Annual
Common stock sold in public and/or at the market offering, net of offering costs	`StockIssuedDuringPeriodValueOther`	$463.28M	USD	Annual
Common stock sold in public and/or at the market offering, net of offering costs	`StockIssuedDuringPeriodValueOther`	$463.28M	USD	Annual
Common stock issued upon exercise of stock options	`StockIssuedDuringPeriodValueStockOptionsExercised`	$1.64M	USD	Annual
Common stock issued upon exercise of stock options	`StockIssuedDuringPeriodValueStockOptionsExercised`	$1.64M	USD	Annual
Common stock issued upon exercise of stock options	`StockIssuedDuringPeriodValueStockOptionsExercised`	$63.00K	USD	Annual
Common stock issued upon exercise of stock options	`StockIssuedDuringPeriodValueStockOptionsExercised`	$63.00K	USD	Annual
Common stock issued upon exercise of stock options	`StockIssuedDuringPeriodValueStockOptionsExercised`	$3.27M	USD	Annual
Common stock issued upon exercise of stock options	`StockIssuedDuringPeriodValueStockOptionsExercised`	$3.27M	USD	Annual
Common stock issued upon exercise of stock options (in shares)	`StockIssuedDuringPeriodSharesStockOptionsExercised`	3.00M	shares	Point-in-time
Common stock issued upon exercise of stock options (in shares)	`StockIssuedDuringPeriodSharesStockOptionsExercised`	3.00M	shares	Point-in-time
Unrealized gain on investments	`OtherComprehensiveIncomeUnrealizedHoldingGainLossOnSecuritiesArisingDuringPeriodNetOfTax`	$-301.00K	USD	Annual
Unrealized gain on investments	`OtherComprehensiveIncomeUnrealizedHoldingGainLossOnSecuritiesArisingDuringPeriodNetOfTax`	$-301.00K	USD	Annual
Unrealized gain on investments	`OtherComprehensiveIncomeUnrealizedHoldingGainLossOnSecuritiesArisingDuringPeriodNetOfTax`	$940.00K	USD	Annual
Unrealized gain on investments	`OtherComprehensiveIncomeUnrealizedHoldingGainLossOnSecuritiesArisingDuringPeriodNetOfTax`	$940.00K	USD	Annual
Unrealized gain on investments	`OtherComprehensiveIncomeUnrealizedHoldingGainLossOnSecuritiesArisingDuringPeriodNetOfTax`	$78.00K	USD	Annual
Unrealized gain on investments	`OtherComprehensiveIncomeUnrealizedHoldingGainLossOnSecuritiesArisingDuringPeriodNetOfTax`	$78.00K	USD	Annual
Foreign currency cumulative translation adjustment	`OtherComprehensiveIncomeLossForeignCurrencyTransactionAndTranslationAdjustmentNetOfTax`	$2.49M	USD	Annual
Foreign currency cumulative translation adjustment	`OtherComprehensiveIncomeLossForeignCurrencyTransactionAndTranslationAdjustmentNetOfTax`	$2.49M	USD	Annual
Foreign currency cumulative translation adjustment	`OtherComprehensiveIncomeLossForeignCurrencyTransactionAndTranslationAdjustmentNetOfTax`	$-3.65M	USD	Annual
Foreign currency cumulative translation adjustment	`OtherComprehensiveIncomeLossForeignCurrencyTransactionAndTranslationAdjustmentNetOfTax`	$-3.65M	USD	Annual
Net Income (Loss)	`NetIncomeLoss`	$-444.04M	USD	Annual
Net Income (Loss)	`NetIncomeLoss`	$-444.04M	USD	Annual
Net Income (Loss)	`NetIncomeLoss`	$-395.89M	USD	Annual
Net Income (Loss)	`NetIncomeLoss`	$-395.89M	USD	Annual
Net Income (Loss)	`NetIncomeLoss`	$-372.18M	USD	Annual
Net Income (Loss)	`NetIncomeLoss`	$-372.18M	USD	Annual
Ending Balance	`StockholdersEquity`	$499.64M	USD	Point-in-time
Ending Balance	`StockholdersEquity`	$499.64M	USD	Point-in-time
Ending Balance	`StockholdersEquity`	$710.40M	USD	Point-in-time
Ending Balance	`StockholdersEquity`	$710.40M	USD	Point-in-time
Ending Balance	`StockholdersEquity`	$621.66M	USD	Point-in-time
Ending Balance	`StockholdersEquity`	$621.66M	USD	Point-in-time
Ending Balance	`StockholdersEquity`	$584.61M	USD	Point-in-time
Ending Balance	`StockholdersEquity`	$584.61M	USD	Point-in-time

Comprehensive Income 22 line items

Line Item	Tag	Value	Unit	Period
Net Loss	`NetIncomeLoss`	$-444.04M	USD	Annual
Net Loss	`NetIncomeLoss`	$-444.04M	USD	Annual
Net Loss	`NetIncomeLoss`	$-395.89M	USD	Annual
Net Loss	`NetIncomeLoss`	$-395.89M	USD	Annual
Net Loss	`NetIncomeLoss`	$-372.18M	USD	Annual
Net Loss	`NetIncomeLoss`	$-372.18M	USD	Annual
Unrealized gain on investments	`OtherComprehensiveIncomeUnrealizedHoldingGainLossOnSecuritiesArisingDuringPeriodNetOfTax`	$-301.00K	USD	Annual
Unrealized gain on investments	`OtherComprehensiveIncomeUnrealizedHoldingGainLossOnSecuritiesArisingDuringPeriodNetOfTax`	$-301.00K	USD	Annual
Unrealized gain on investments	`OtherComprehensiveIncomeUnrealizedHoldingGainLossOnSecuritiesArisingDuringPeriodNetOfTax`	$940.00K	USD	Annual
Unrealized gain on investments	`OtherComprehensiveIncomeUnrealizedHoldingGainLossOnSecuritiesArisingDuringPeriodNetOfTax`	$940.00K	USD	Annual
Unrealized gain on investments	`OtherComprehensiveIncomeUnrealizedHoldingGainLossOnSecuritiesArisingDuringPeriodNetOfTax`	$78.00K	USD	Annual
Unrealized gain on investments	`OtherComprehensiveIncomeUnrealizedHoldingGainLossOnSecuritiesArisingDuringPeriodNetOfTax`	$78.00K	USD	Annual
Foreign currency translation adjustment	`OtherComprehensiveIncomeLossForeignCurrencyTransactionAndTranslationAdjustmentNetOfTax`	$2.49M	USD	Annual
Foreign currency translation adjustment	`OtherComprehensiveIncomeLossForeignCurrencyTransactionAndTranslationAdjustmentNetOfTax`	$2.49M	USD	Annual
Foreign currency translation adjustment	`OtherComprehensiveIncomeLossForeignCurrencyTransactionAndTranslationAdjustmentNetOfTax`	$-3.65M	USD	Annual
Foreign currency translation adjustment	`OtherComprehensiveIncomeLossForeignCurrencyTransactionAndTranslationAdjustmentNetOfTax`	$-3.65M	USD	Annual
Comprehensive Loss	`ComprehensiveIncomeNetOfTax`	$-396.19M	USD	Annual
Comprehensive Loss	`ComprehensiveIncomeNetOfTax`	$-396.19M	USD	Annual
Comprehensive Loss	`ComprehensiveIncomeNetOfTax`	$-440.61M	USD	Annual
Comprehensive Loss	`ComprehensiveIncomeNetOfTax`	$-440.61M	USD	Annual
Comprehensive Loss	`ComprehensiveIncomeNetOfTax`	$-375.75M	USD	Annual
Comprehensive Loss	`ComprehensiveIncomeNetOfTax`	$-375.75M	USD	Annual

Data is extracted from SEC EDGAR XBRL filings. Values shown are as reported in the filing.