10-K Filing

IOVANCE BIOTHERAPEUTICS, INC. CIK: 1425205 FY 2020

Filing Information

Form Type	10-K
Accession Number	`0001558370-21-001858`
Period End Date	20201231
Filing Date	20210225
Fiscal Year	2020
Fiscal Period	FY
XBRL Instance	iova-20201231x10k_htm.xml

Filing Contents

This filing contains the following financial statements:

Balance Sheet 61 Income Statement 48 Cash Flow Statement 84 Stockholders Equity 40 Comprehensive Income 17

Balance Sheet 61 line items

Line Item	Tag	Value	Unit	Period
Cash and cash equivalents	`CashAndCashEquivalentsAtCarryingValue`	$67.33M	USD	Point-in-time
Cash and cash equivalents	`CashAndCashEquivalentsAtCarryingValue`	$82.15M	USD	Point-in-time
Cash and cash equivalents	`CashAndCashEquivalentsAtCarryingValue`	$13.97M	USD	Point-in-time
Short-term investments	`ShortTermInvestments`	$562.11M	USD	Point-in-time
Short-term investments	`ShortTermInvestments`	$293.11M	USD	Point-in-time
Prepaid expenses and other assets	`PrepaidExpenseAndOtherAssetsCurrent`	$6.66M	USD	Point-in-time
Prepaid expenses and other assets	`PrepaidExpenseAndOtherAssetsCurrent`	$9.41M	USD	Point-in-time
Total Current Assets	`AssetsCurrent`	$316.49M	USD	Point-in-time
Total Current Assets	`AssetsCurrent`	$636.10M	USD	Point-in-time
Property and equipment, net	`PropertyPlantAndEquipmentNet`	$8.54M	USD	Point-in-time
Property and equipment, net	`PropertyPlantAndEquipmentNet`	$59.16M	USD	Point-in-time
Common stock, par or stated value per share	`CommonStockParOrStatedValuePerShare`	-	USD	Point-in-time
Common stock, par or stated value per share	`CommonStockParOrStatedValuePerShare`	-	USD	Point-in-time
Common stock, par or stated value per share	`CommonStockParOrStatedValuePerShare`	-	USD	Point-in-time
Operating lease right-of-use assets	`OperatingLeaseRightOfUseAsset`	$10.70M	USD	Point-in-time
Operating lease right-of-use assets	`OperatingLeaseRightOfUseAsset`	$54.76M	USD	Point-in-time
Common stock, shares authorized	`CommonStockSharesAuthorized`	150.00M	shares	Point-in-time
Common stock, shares authorized	`CommonStockSharesAuthorized`	300.00M	shares	Point-in-time
Restricted cash	`RestrictedCash`	$5.45M	USD	Point-in-time
Restricted cash	`RestrictedCash`	$5.53M	USD	Point-in-time
Common stock, shares authorized	`CommonStockSharesAuthorized`	300.00M	shares	Point-in-time
Long-term assets	`OtherAssetsNoncurrent`	$12.92M	USD	Point-in-time
Common Stock, Shares, Issued	`CommonStockSharesIssued`	146.87M	shares	Point-in-time
Long-term assets	`OtherAssetsNoncurrent`	$3.48M	USD	Point-in-time
Common Stock, Shares, Issued	`CommonStockSharesIssued`	126.41M	shares	Point-in-time
Total Assets	`Assets`	$344.65M	USD	Point-in-time
Common Stock, Shares, Outstanding	`CommonStockSharesOutstanding`	126.41M	shares	Point-in-time
Total Assets	`Assets`	$768.46M	USD	Point-in-time
Common Stock, Shares, Outstanding	`CommonStockSharesOutstanding`	146.87M	shares	Point-in-time
Accounts payable	`AccountsPayableCurrent`	$15.57M	USD	Point-in-time
Accounts payable	`AccountsPayableCurrent`	$13.51M	USD	Point-in-time
Accrued expenses	`AccruedLiabilitiesCurrent`	$35.07M	USD	Point-in-time
Accrued expenses	`AccruedLiabilitiesCurrent`	$16.27M	USD	Point-in-time
Operating lease liabilities - current	`OperatingLeaseLiabilityCurrent`	$7.25M	USD	Point-in-time
Operating lease liabilities - current	`OperatingLeaseLiabilityCurrent`	$6.28M	USD	Point-in-time
Total Current Liabilities	`LiabilitiesCurrent`	$39.08M	USD	Point-in-time
Total Current Liabilities	`LiabilitiesCurrent`	$54.87M	USD	Point-in-time
Operating lease liabilities - noncurrent	`OperatingLeaseLiabilityNoncurrent`	$45.38M	USD	Point-in-time
Operating lease liabilities - noncurrent	`OperatingLeaseLiabilityNoncurrent`	$4.25M	USD	Point-in-time
Other liabilities	`OtherLiabilitiesNoncurrent`	$11.71M	USD	Point-in-time
Other liabilities	`OtherLiabilitiesNoncurrent`	$2.35M	USD	Point-in-time
Total Non-Current Liabilities	`LiabilitiesNoncurrent`	$57.09M	USD	Point-in-time
Total Non-Current Liabilities	`LiabilitiesNoncurrent`	$6.60M	USD	Point-in-time
Total Liabilities	`Liabilities`	$111.96M	USD	Point-in-time
Total Liabilities	`Liabilities`	$45.68M	USD	Point-in-time
Commitments and contingencies (Note 10 and 11)	`CommitmentsAndContingencies`	-	USD	Point-in-time
Commitments and contingencies (Note 10 and 11)	`CommitmentsAndContingencies`	-	USD	Point-in-time
Common stock, $0.000041666 par value; 300,000,000 shares authorized, 146,874,917 and 126,411,808 shares issued and outstanding as of December 31, 2020 and December 31, 2019, respectively	`CommonStockValue`	$6.00K	USD	Point-in-time
Common stock, $0.000041666 par value; 300,000,000 shares authorized, 146,874,917 and 126,411,808 shares issued and outstanding as of December 31, 2020 and December 31, 2019, respectively	`CommonStockValue`	$5.00K	USD	Point-in-time
Accumulated other comprehensive income	`AccumulatedOtherComprehensiveIncomeLossNetOfTax`	$220.00K	USD	Point-in-time
Accumulated other comprehensive income	`AccumulatedOtherComprehensiveIncomeLossNetOfTax`	$19.00K	USD	Point-in-time
Additional paid-in capital	`AdditionalPaidInCapital`	$869.35M	USD	Point-in-time
Additional paid-in capital	`AdditionalPaidInCapital`	$1.49B	USD	Point-in-time
Accumulated deficit	`RetainedEarningsAccumulatedDeficit`	$-830.19M	USD	Point-in-time
Accumulated deficit	`RetainedEarningsAccumulatedDeficit`	$-570.61M	USD	Point-in-time
Total Stockholders' Equity	`StockholdersEquity`	$145.48M	USD	Point-in-time
Total Stockholders' Equity	`StockholdersEquity`	$466.19M	USD	Point-in-time
Total Stockholders' Equity	`StockholdersEquity`	$298.97M	USD	Point-in-time
Total Stockholders' Equity	`StockholdersEquity`	$656.50M	USD	Point-in-time
Total Liabilities and Stockholders' Equity	`LiabilitiesAndStockholdersEquity`	$768.46M	USD	Point-in-time
Total Liabilities and Stockholders' Equity	`LiabilitiesAndStockholdersEquity`	$344.65M	USD	Point-in-time

Income Statement 48 line items

Line Item	Tag	Value	Unit	Period
Research and development expenses	`ResearchAndDevelopmentExpense`	$201.73M	USD	Annual
Research and development expenses	`ResearchAndDevelopmentExpense`	$99.83M	USD	Annual
Research and development expenses	`ResearchAndDevelopmentExpense`	$166.02M	USD	Annual
General and administrative expenses	`GeneralAndAdministrativeExpense`	$40.85M	USD	Annual
General and administrative expenses	`GeneralAndAdministrativeExpense`	$60.21M	USD	Annual
General and administrative expenses	`GeneralAndAdministrativeExpense`	$28.43M	USD	Annual
Total costs and expenses	`OperatingExpenses`	$261.94M	USD	Annual
Total costs and expenses	`OperatingExpenses`	$128.26M	USD	Annual
Total costs and expenses	`OperatingExpenses`	$206.87M	USD	Annual
Loss from operations	`OperatingIncomeLoss`	$-206.87M	USD	Annual
Loss from operations	`OperatingIncomeLoss`	$-261.94M	USD	Annual
Loss from operations	`OperatingIncomeLoss`	$-128.26M	USD	Annual
Interest income, net	`InvestmentIncomeInterest`	$9.32M	USD	Annual
Interest income, net	`InvestmentIncomeInterest`	$4.68M	USD	Annual
Interest income, net	`InvestmentIncomeInterest`	$2.36M	USD	Annual
Net Loss	`NetIncomeLoss`	$-69.59M	USD	1 Quarter
Net Loss	`NetIncomeLoss`	$-68.40M	USD	1 Quarter
Net Loss	`NetIncomeLoss`	$-123.58M	USD	Annual
Net Loss	`NetIncomeLoss`	$-259.58M	USD	Annual
Net Loss	`NetIncomeLoss`	$-197.56M	USD	Annual
Net Loss	`NetIncomeLoss`	$-47.55M	USD	1 Quarter
Net Loss	`NetIncomeLoss`	$-63.57M	USD	1 Quarter
Net Loss	`NetIncomeLoss`	$-36.95M	USD	1 Quarter
Net Loss	`NetIncomeLoss`	$-58.57M	USD	1 Quarter
Net Loss	`NetIncomeLoss`	$-63.02M	USD	1 Quarter
Net Loss	`NetIncomeLoss`	$-49.49M	USD	1 Quarter
Net Loss Per Share of Common Stock, Basic and Diluted	`EarningsPerShareBasicAndDiluted`	$-1.27	USD	Annual
Net Loss Per Share of Common Stock, Basic and Diluted	`EarningsPerShareBasicAndDiluted`	$-0.55	USD	1 Quarter
Net Loss Per Share of Common Stock, Basic and Diluted	`EarningsPerShareBasicAndDiluted`	$-0.40	USD	1 Quarter
Net Loss Per Share of Common Stock, Basic and Diluted	`EarningsPerShareBasicAndDiluted`	$-1.88	USD	Annual
Net Loss Per Share of Common Stock, Basic and Diluted	`EarningsPerShareBasicAndDiluted`	$-0.50	USD	1 Quarter
Net Loss Per Share of Common Stock, Basic and Diluted	`EarningsPerShareBasicAndDiluted`	$-0.38	USD	1 Quarter
Net Loss Per Share of Common Stock, Basic and Diluted	`EarningsPerShareBasicAndDiluted`	$-0.30	USD	1 Quarter
Net Loss Per Share of Common Stock, Basic and Diluted	`EarningsPerShareBasicAndDiluted`	$-1.59	USD	Annual
Net Loss Per Share of Common Stock, Basic and Diluted	`EarningsPerShareBasicAndDiluted`	$-0.47	USD	1 Quarter
Net Loss Per Share of Common Stock, Basic and Diluted	`EarningsPerShareBasicAndDiluted`	$-0.40	USD	1 Quarter
Net Loss Per Share of Common Stock, Basic and Diluted	`EarningsPerShareBasicAndDiluted`	$-0.47	USD	1 Quarter
Weighted Average Shares of Common Stock Outstanding, Basic and Diluted	`WeightedAverageNumberOfShareOutstandingBasicAndDiluted`	146,738.00	shares	1 Quarter
Weighted Average Shares of Common Stock Outstanding, Basic and Diluted	`WeightedAverageNumberOfShareOutstandingBasicAndDiluted`	146,492.00	shares	1 Quarter
Weighted Average Shares of Common Stock Outstanding, Basic and Diluted	`WeightedAverageNumberOfShareOutstandingBasicAndDiluted`	123,415.00	shares	1 Quarter
Weighted Average Shares of Common Stock Outstanding, Basic and Diluted	`WeightedAverageNumberOfShareOutstandingBasicAndDiluted`	124,336.00	shares	Annual
Weighted Average Shares of Common Stock Outstanding, Basic and Diluted	`WeightedAverageNumberOfShareOutstandingBasicAndDiluted`	97,277.00	shares	Annual
Weighted Average Shares of Common Stock Outstanding, Basic and Diluted	`WeightedAverageNumberOfShareOutstandingBasicAndDiluted`	138,301.00	shares	Annual
Weighted Average Shares of Common Stock Outstanding, Basic and Diluted	`WeightedAverageNumberOfShareOutstandingBasicAndDiluted`	133,162.00	shares	1 Quarter
Weighted Average Shares of Common Stock Outstanding, Basic and Diluted	`WeightedAverageNumberOfShareOutstandingBasicAndDiluted`	126,568.00	shares	1 Quarter
Weighted Average Shares of Common Stock Outstanding, Basic and Diluted	`WeightedAverageNumberOfShareOutstandingBasicAndDiluted`	124,035.00	shares	1 Quarter
Weighted Average Shares of Common Stock Outstanding, Basic and Diluted	`WeightedAverageNumberOfShareOutstandingBasicAndDiluted`	126,273.00	shares	1 Quarter
Weighted Average Shares of Common Stock Outstanding, Basic and Diluted	`WeightedAverageNumberOfShareOutstandingBasicAndDiluted`	123,567.00	shares	1 Quarter

Cash Flow Statement 84 line items

Line Item	Tag	Value	Unit	Period
Net loss	`NetIncomeLoss`	$-69.59M	USD	1 Quarter
Net loss	`NetIncomeLoss`	$-68.40M	USD	1 Quarter
Net loss	`NetIncomeLoss`	$-123.58M	USD	Annual
Net loss	`NetIncomeLoss`	$-259.58M	USD	Annual
Net loss	`NetIncomeLoss`	$-197.56M	USD	Annual
Net loss	`NetIncomeLoss`	$-47.55M	USD	1 Quarter
Net loss	`NetIncomeLoss`	$-63.57M	USD	1 Quarter
Net loss	`NetIncomeLoss`	$-36.95M	USD	1 Quarter
Net loss	`NetIncomeLoss`	$-58.57M	USD	1 Quarter
Net loss	`NetIncomeLoss`	$-63.02M	USD	1 Quarter
Net loss	`NetIncomeLoss`	$-49.49M	USD	1 Quarter
Stock-based compensation expense	`ShareBasedCompensation`	$24.28M	USD	Annual
Stock-based compensation expense	`ShareBasedCompensation`	$20.03M	USD	Annual
Stock-based compensation expense	`ShareBasedCompensation`	$40.89M	USD	Annual
Noncash lease expense	`NonCashLeaseExpense`	$7.57M	USD	Annual
Noncash lease expense	`NonCashLeaseExpense`	$6.95M	USD	Annual
Depreciation and amortization	`DepreciationDepletionAndAmortization`	$956.00K	USD	Annual
Depreciation and amortization	`DepreciationDepletionAndAmortization`	$1.14M	USD	Annual
Depreciation and amortization	`DepreciationDepletionAndAmortization`	$1.17M	USD	Annual
Gain on settlement of dispute	`GainLossRelatedToLitigationSettlement`	$336.00K	USD	Annual
Accretion (amortization) of discounts and premiums on investments	`AmortizationOfDebtDiscountPremium`	$1.86M	USD	Annual
Accretion (amortization) of discounts and premiums on investments	`AmortizationOfDebtDiscountPremium`	$-3.42M	USD	Annual
Accretion (amortization) of discounts and premiums on investments	`AmortizationOfDebtDiscountPremium`	$-1.33M	USD	Annual
Loss on disposal of assets	`GainLossOnDispositionOfAssets`	$-9.00K	USD	Annual
Loss on disposal of assets	`GainLossOnDispositionOfAssets`	$-16.00K	USD	Annual
Prepaid expenses, other assets, and long-term assets	`IncreaseDecreaseInPrepaidDeferredExpenseAndOtherAssets`	$6.69M	USD	Annual
Prepaid expenses, other assets, and long-term assets	`IncreaseDecreaseInPrepaidDeferredExpenseAndOtherAssets`	$2.06M	USD	Annual
Prepaid expenses, other assets, and long-term assets	`IncreaseDecreaseInPrepaidDeferredExpenseAndOtherAssets`	$3.28M	USD	Annual
Operating lease liabilities (Right-of-use assets)	`IncreaseDecreaseInOperatingLeaseRightOfUseAsset`	$-6.15M	USD	Annual
Operating lease liabilities (Right-of-use assets)	`IncreaseDecreaseInOperatingLeaseRightOfUseAsset`	$-11.47M	USD	Annual
Accounts payable	`IncreaseDecreaseInAccountsPayable`	$12.71M	USD	Annual
Accounts payable	`IncreaseDecreaseInAccountsPayable`	$1.51M	USD	Annual
Accounts payable	`IncreaseDecreaseInAccountsPayable`	$-2.96M	USD	Annual
Accrued expenses and other liabilities	`IncreaseDecreaseInAccruedLiabilities`	$3.23M	USD	Annual
Accrued expenses and other liabilities	`IncreaseDecreaseInAccruedLiabilities`	$6.73M	USD	Annual
Accrued expenses and other liabilities	`IncreaseDecreaseInAccruedLiabilities`	$24.11M	USD	Annual
Net cash used in operating activities	`NetCashProvidedByUsedInOperatingActivities`	$-101.25M	USD	Annual
Net cash used in operating activities	`NetCashProvidedByUsedInOperatingActivities`	$-205.13M	USD	Annual
Net cash used in operating activities	`NetCashProvidedByUsedInOperatingActivities`	$-158.89M	USD	Annual
Maturities of short-term investments	`ProceedsFromSaleAndMaturityOfAvailableForSaleSecurities`	$41.00M	USD	Annual
Maturities of short-term investments	`ProceedsFromSaleAndMaturityOfAvailableForSaleSecurities`	$514.60M	USD	Annual
Maturities of short-term investments	`ProceedsFromSaleAndMaturityOfAvailableForSaleSecurities`	$676.60M	USD	Annual
Purchase of short-term investments	`PaymentsToAcquireAvailableForSaleSecuritiesDebt`	$426.08M	USD	Annual
Purchase of short-term investments	`PaymentsToAcquireAvailableForSaleSecuritiesDebt`	$947.66M	USD	Annual
Purchase of short-term investments	`PaymentsToAcquireAvailableForSaleSecuritiesDebt`	$417.66M	USD	Annual
Purchase of property and equipment	`PaymentsToAcquirePropertyPlantAndEquipment`	$1.20M	USD	Annual
Purchase of property and equipment	`PaymentsToAcquirePropertyPlantAndEquipment`	$6.92M	USD	Annual
Purchase of property and equipment	`PaymentsToAcquirePropertyPlantAndEquipment`	$46.79M	USD	Annual
Net cash (used in) provided by investing activities	`NetCashProvidedByUsedInInvestingActivities`	$-386.28M	USD	Annual
Net cash (used in) provided by investing activities	`NetCashProvidedByUsedInInvestingActivities`	$-317.85M	USD	Annual
Net cash (used in) provided by investing activities	`NetCashProvidedByUsedInInvestingActivities`	$90.03M	USD	Annual
Tax payments related to shares withheld for vested restricted stock units	`PaymentsRelatedToTaxWithholdingForShareBasedCompensation`	$284.00K	USD	Annual
Tax payments related to shares withheld for vested restricted stock units	`PaymentsRelatedToTaxWithholdingForShareBasedCompensation`	$312.00K	USD	Annual
Tax payments related to shares withheld for vested restricted stock units	`PaymentsRelatedToTaxWithholdingForShareBasedCompensation`	$223.00K	USD	Annual
Proceeds from the issuance of common stock upon exercise of warrants	`ProceedsFromWarrantExercises`	$15.75M	USD	Annual
Proceeds from the issuance of common stock upon exercise of options	`ProceedsFromStockOptionsExercised`	$9.66M	USD	Annual
Proceeds from the issuance of common stock upon exercise of options	`ProceedsFromStockOptionsExercised`	$6.44M	USD	Annual
Proceeds from the issuance of common stock upon exercise of options	`ProceedsFromStockOptionsExercised`	$9.96M	USD	Annual
Proceeds from the issuance of common stock, net	`ProceedsFromIssuanceOfCommonStock`	$398.82M	USD	Annual
Proceeds from the issuance of common stock, net	`ProceedsFromIssuanceOfCommonStock`	$162.00M	USD	Point-in-time
Proceeds from the issuance of common stock, net	`ProceedsFromIssuanceOfCommonStock`	$236.70M	USD	Point-in-time
Proceeds from the issuance of common stock, net	`ProceedsFromIssuanceOfCommonStock`	$567.04M	USD	Annual
Net cash provided by financing activities	`NetCashProvidedByUsedInFinancingActivities`	$6.13M	USD	Annual
Net cash provided by financing activities	`NetCashProvidedByUsedInFinancingActivities`	$576.42M	USD	Annual
Net cash provided by financing activities	`NetCashProvidedByUsedInFinancingActivities`	$424.31M	USD	Annual
Net increase (decrease) in cash, cash equivalents, and restricted cash	`CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseExcludingExchangeRateEffect`	$53.44M	USD	Annual
Net increase (decrease) in cash, cash equivalents, and restricted cash	`CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseExcludingExchangeRateEffect`	$-63.22M	USD	Annual
Net increase (decrease) in cash, cash equivalents, and restricted cash	`CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseExcludingExchangeRateEffect`	$-62.73M	USD	Annual
Cash, Cash Equivalents, and Restricted Cash Beginning of Year	`CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents`	$145.37M	USD	Point-in-time
Cash, Cash Equivalents, and Restricted Cash Beginning of Year	`CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents`	$82.15M	USD	Point-in-time
Cash, Cash Equivalents, and Restricted Cash Beginning of Year	`CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents`	$72.85M	USD	Point-in-time
Cash, Cash Equivalents, and Restricted Cash Beginning of Year	`CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents`	$19.42M	USD	Point-in-time
Cash, Cash Equivalents, and Restricted Cash End of Year	`CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents`	$145.37M	USD	Point-in-time
Cash, Cash Equivalents, and Restricted Cash End of Year	`CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents`	$82.15M	USD	Point-in-time
Cash, Cash Equivalents, and Restricted Cash End of Year	`CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents`	$72.85M	USD	Point-in-time
Cash, Cash Equivalents, and Restricted Cash End of Year	`CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents`	$19.42M	USD	Point-in-time
Net unrealized (loss) gain on short-term investments	`UnrealizedGainLossOnShortTermInvestments`	$262.00K	USD	Annual
Net unrealized (loss) gain on short-term investments	`UnrealizedGainLossOnShortTermInvestments`	$-201.00K	USD	Annual
Net unrealized (loss) gain on short-term investments	`UnrealizedGainLossOnShortTermInvestments`	$-42.00K	USD	Annual
Acquisitions of property and equipment included in accounts payable and accrued expense	`AcquisitionsOfPropertyAndEquipmentIncludedInAccountsPayableAndAccruedExpense`	$5.09M	USD	Annual
Acquisitions of property and equipment included in accounts payable and accrued expense	`AcquisitionsOfPropertyAndEquipmentIncludedInAccountsPayableAndAccruedExpense`	$-122.00K	USD	Annual
Conversion of convertible preferred stock to common stock	`ConversionOfStockAmountConverted1`	$1.00K	USD	Annual
Conversion of convertible preferred stock to common stock	`ConversionOfStockAmountConverted1`	$2.00K	USD	Annual
Vesting of restricted stock units	`VestingOfRestrictedStockUnits`	$1.00K	USD	Annual

Stockholders Equity 40 line items

Line Item	Tag	Value	Unit	Period
Beginning Balance	`StockholdersEquity`	$145.48M	USD	Point-in-time
Beginning Balance	`StockholdersEquity`	$466.19M	USD	Point-in-time
Beginning Balance	`StockholdersEquity`	$298.97M	USD	Point-in-time
Beginning Balance	`StockholdersEquity`	$656.50M	USD	Point-in-time
Stock-based compensation expense	`AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue`	$40.77M	USD	Annual
Stock-based compensation expense	`AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue`	$24.28M	USD	Annual
Stock-based compensation expense	`AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue`	$20.03M	USD	Annual
Vesting of restricted shares issued for services	`StockIssuedDuringPeriodValueRestrictedStockAwardNetOfForfeitures`	$112.00K	USD	Annual
Tax payments related to shares withheld for vested restricted stock units	`AdjustmentToAdditionalPaidInCapitalIncomeTaxEffectFromShareBasedCompensationNet`	$-284.00K	USD	Annual
Tax payments related to shares withheld for vested restricted stock units	`AdjustmentToAdditionalPaidInCapitalIncomeTaxEffectFromShareBasedCompensationNet`	$-223.00K	USD	Annual
Tax payments related to shares withheld for vested restricted stock units	`AdjustmentToAdditionalPaidInCapitalIncomeTaxEffectFromShareBasedCompensationNet`	$-312.00K	USD	Annual
Common stock issued upon exercise of warrants	`CommonStockIssuedUponExerciseOfWarrantsAmount`	$15.75M	USD	Annual
Common stock issued upon exercise of stock options	`StockIssuedDuringPeriodValueStockOptionsExercised`	$9.66M	USD	Annual
Common stock issued upon exercise of stock options	`StockIssuedDuringPeriodValueStockOptionsExercised`	$6.44M	USD	Annual
Common stock issued upon exercise of stock options	`StockIssuedDuringPeriodValueStockOptionsExercised`	$9.96M	USD	Annual
Common stock issued upon exercise of stock options (in shares)	`StockIssuedDuringPeriodSharesStockOptionsExercised`	973,854.00	shares	Annual
Common stock issued upon exercise of stock options (in shares)	`StockIssuedDuringPeriodSharesStockOptionsExercised`	727,492.00	shares	Annual
Common stock issued upon exercise of stock options (in shares)	`StockIssuedDuringPeriodSharesStockOptionsExercised`	1.34M	shares	Annual
Unrealized (loss) / gain on short-term investments	`OtherComprehensiveIncomeUnrealizedHoldingGainLossOnSecuritiesArisingDuringPeriodNetOfTax`	$-201.00K	USD	Annual
Unrealized (loss) / gain on short-term investments	`OtherComprehensiveIncomeUnrealizedHoldingGainLossOnSecuritiesArisingDuringPeriodNetOfTax`	$262.00K	USD	Annual
Unrealized (loss) / gain on short-term investments	`OtherComprehensiveIncomeUnrealizedHoldingGainLossOnSecuritiesArisingDuringPeriodNetOfTax`	$-42.00K	USD	Annual
Common stock sold in public offering, net of offering costs	`StockIssuedDuringPeriodValueNewIssues`	$398.82M	USD	Annual
Common stock sold in public offering, net of offering costs	`StockIssuedDuringPeriodValueNewIssues`	$567.04M	USD	Annual
Common stock sold in public offering, net of offering costs (in shares)	`StockIssuedDuringPeriodSharesNewIssues`	50,000.00	shares	Point-in-time
Cancellation of common shares from settlement of dispute	`StockCancelledDuringPeriodSharesOfCommonStock`	$-336.00K	USD	Annual
Net loss	`NetIncomeLoss`	$-69.59M	USD	1 Quarter
Net loss	`NetIncomeLoss`	$-68.40M	USD	1 Quarter
Net loss	`NetIncomeLoss`	$-123.58M	USD	Annual
Net loss	`NetIncomeLoss`	$-259.58M	USD	Annual
Net loss	`NetIncomeLoss`	$-197.56M	USD	Annual
Net loss	`NetIncomeLoss`	$-47.55M	USD	1 Quarter
Net loss	`NetIncomeLoss`	$-63.57M	USD	1 Quarter
Net loss	`NetIncomeLoss`	$-36.95M	USD	1 Quarter
Net loss	`NetIncomeLoss`	$-58.57M	USD	1 Quarter
Net loss	`NetIncomeLoss`	$-63.02M	USD	1 Quarter
Net loss	`NetIncomeLoss`	$-49.49M	USD	1 Quarter
Ending Balance	`StockholdersEquity`	$145.48M	USD	Point-in-time
Ending Balance	`StockholdersEquity`	$466.19M	USD	Point-in-time
Ending Balance	`StockholdersEquity`	$298.97M	USD	Point-in-time
Ending Balance	`StockholdersEquity`	$656.50M	USD	Point-in-time

Comprehensive Income 17 line items

Line Item	Tag	Value	Unit	Period
Net Loss	`NetIncomeLoss`	$-69.59M	USD	1 Quarter
Net Loss	`NetIncomeLoss`	$-68.40M	USD	1 Quarter
Net Loss	`NetIncomeLoss`	$-123.58M	USD	Annual
Net Loss	`NetIncomeLoss`	$-259.58M	USD	Annual
Net Loss	`NetIncomeLoss`	$-197.56M	USD	Annual
Net Loss	`NetIncomeLoss`	$-47.55M	USD	1 Quarter
Net Loss	`NetIncomeLoss`	$-63.57M	USD	1 Quarter
Net Loss	`NetIncomeLoss`	$-36.95M	USD	1 Quarter
Net Loss	`NetIncomeLoss`	$-58.57M	USD	1 Quarter
Net Loss	`NetIncomeLoss`	$-63.02M	USD	1 Quarter
Net Loss	`NetIncomeLoss`	$-49.49M	USD	1 Quarter
Unrealized (loss) / gain on short-term investments	`OtherComprehensiveIncomeUnrealizedHoldingGainLossOnSecuritiesArisingDuringPeriodNetOfTax`	$-201.00K	USD	Annual
Unrealized (loss) / gain on short-term investments	`OtherComprehensiveIncomeUnrealizedHoldingGainLossOnSecuritiesArisingDuringPeriodNetOfTax`	$262.00K	USD	Annual
Unrealized (loss) / gain on short-term investments	`OtherComprehensiveIncomeUnrealizedHoldingGainLossOnSecuritiesArisingDuringPeriodNetOfTax`	$-42.00K	USD	Annual
Comprehensive Loss	`ComprehensiveIncomeNetOfTax`	$-259.78M	USD	Annual
Comprehensive Loss	`ComprehensiveIncomeNetOfTax`	$-123.62M	USD	Annual
Comprehensive Loss	`ComprehensiveIncomeNetOfTax`	$-197.29M	USD	Annual

Data is extracted from SEC EDGAR XBRL filings. Values shown are as reported in the filing.