10-K Filing

CELLDEX THERAPEUTICS, INC. CIK: 744218 FY 2023

Filing Information

Form Type	10-K
Accession Number	`0001410578-24-000076`
Period End Date	20231231
Filing Date	20240226
Fiscal Year	2023
Fiscal Period	FY
XBRL Instance	cldx-20231231x10k_htm.xml

Filing Contents

This filing contains the following financial statements:

Balance Sheet 70 Income Statement 51 Cash Flow Statement 71 Stockholders Equity 26

Balance Sheet 70 line items

Line Item	Tag	Value	Unit	Period
Convertible preferred stock, par value (in dollars per share)	`PreferredStockParOrStatedValuePerShare`	$0.01	USD	Point-in-time
Convertible preferred stock, par value (in dollars per share)	`PreferredStockParOrStatedValuePerShare`	$0.01	USD	Point-in-time
Convertible preferred stock, shares authorized (in shares)	`PreferredStockSharesAuthorized`	3.00M	shares	Point-in-time
Convertible preferred stock, shares authorized (in shares)	`PreferredStockSharesAuthorized`	3.00M	shares	Point-in-time
Cash and cash equivalents	`CashAndCashEquivalentsAtCarryingValue`	$29.43M	USD	Point-in-time
Convertible preferred stock, shares issued (in shares)	`PreferredStockSharesIssued`	0.00	shares	Point-in-time
Cash and cash equivalents	`CashAndCashEquivalentsAtCarryingValue`	$34.81M	USD	Point-in-time
Convertible preferred stock, shares issued (in shares)	`PreferredStockSharesIssued`	0.00	shares	Point-in-time
Convertible preferred stock, shares outstanding (in shares)	`PreferredStockSharesOutstanding`	0.00	shares	Point-in-time
Convertible preferred stock, shares outstanding (in shares)	`PreferredStockSharesOutstanding`	0.00	shares	Point-in-time
Marketable securities	`MarketableSecuritiesCurrent`	$388.78M	USD	Point-in-time
Marketable securities	`MarketableSecuritiesCurrent`	$275.52M	USD	Point-in-time
Common stock, par value (in dollars per share)	`CommonStockParOrStatedValuePerShare`	$0.00	USD	Point-in-time
Common stock, par value (in dollars per share)	`CommonStockParOrStatedValuePerShare`	$0.00	USD	Point-in-time
Accounts and other receivables	`AccountsAndOtherReceivablesNetCurrent`	$2.63M	USD	Point-in-time
Accounts and other receivables	`AccountsAndOtherReceivablesNetCurrent`	$347.00K	USD	Point-in-time
Prepaid and other current assets	`PrepaidExpenseAndOtherAssetsCurrent`	$12.39M	USD	Point-in-time
Common stock, shares authorized (in shares)	`CommonStockSharesAuthorized`	297.00M	shares	Point-in-time
Common stock, shares authorized (in shares)	`CommonStockSharesAuthorized`	297.00M	shares	Point-in-time
Prepaid and other current assets	`PrepaidExpenseAndOtherAssetsCurrent`	$5.47M	USD	Point-in-time
Common stock, shares issued (in shares)	`CommonStockSharesIssued`	47.20M	shares	Point-in-time
Common stock, shares issued (in shares)	`CommonStockSharesIssued`	55.88M	shares	Point-in-time
Total current assets	`AssetsCurrent`	$431.69M	USD	Point-in-time
Total current assets	`AssetsCurrent`	$317.69M	USD	Point-in-time
Property and equipment, net	`PropertyPlantAndEquipmentNet`	$4.06M	USD	Point-in-time
Property and equipment, net	`PropertyPlantAndEquipmentNet`	$3.75M	USD	Point-in-time
Common stock, shares outstanding (in shares)	`CommonStockSharesOutstanding`	55.88M	shares	Point-in-time
Common stock, shares outstanding (in shares)	`CommonStockSharesOutstanding`	47.20M	shares	Point-in-time
Operating lease right-of-use assets, net	`OperatingLeaseRightOfUseAsset`	$4.00M	USD	Point-in-time
Operating lease right-of-use assets, net	`OperatingLeaseRightOfUseAsset`	$2.58M	USD	Point-in-time
Intangible assets	`IntangibleAssetsNetExcludingGoodwill`	$27.19M	USD	Point-in-time
Intangible assets	`IntangibleAssetsNetExcludingGoodwill`	$27.19M	USD	Point-in-time
Other assets	`OtherAssetsNoncurrent`	$104.00K	USD	Point-in-time
Other assets	`OtherAssetsNoncurrent`	$107.00K	USD	Point-in-time
Total assets	`Assets`	$465.63M	USD	Point-in-time
Total assets	`Assets`	$352.74M	USD	Point-in-time
Accounts payable	`AccountsPayableCurrent`	$3.49M	USD	Point-in-time
Accounts payable	`AccountsPayableCurrent`	$3.34M	USD	Point-in-time
Accrued expenses	`AccruedLiabilitiesCurrent`	$22.03M	USD	Point-in-time
Accrued expenses	`AccruedLiabilitiesCurrent`	$12.84M	USD	Point-in-time
Current portion of operating lease liabilities	`OperatingLeaseLiabilityCurrent`	$1.45M	USD	Point-in-time
Current portion of operating lease liabilities	`OperatingLeaseLiabilityCurrent`	$1.61M	USD	Point-in-time
Current portion of long-term liabilities	`OtherLiabilitiesCurrent`	$990.00K	USD	Point-in-time
Current portion of long-term liabilities	`OtherLiabilitiesCurrent`	$3.99M	USD	Point-in-time
Total current liabilities	`LiabilitiesCurrent`	$31.12M	USD	Point-in-time
Total current liabilities	`LiabilitiesCurrent`	$18.61M	USD	Point-in-time
Long-term portion of operating lease liabilities	`OperatingLeaseLiabilityNoncurrent`	$928.00K	USD	Point-in-time
Long-term portion of operating lease liabilities	`OperatingLeaseLiabilityNoncurrent`	$2.59M	USD	Point-in-time
Other long-term liabilities	`OtherLiabilitiesNoncurrent`	$5.33M	USD	Point-in-time
Other long-term liabilities	`OtherLiabilitiesNoncurrent`	$4.40M	USD	Point-in-time
Total liabilities	`Liabilities`	$26.53M	USD	Point-in-time
Total liabilities	`Liabilities`	$36.46M	USD	Point-in-time
Commitments and contingent liabilities (Note 14)	`CommitmentsAndContingencies`	-	USD	Point-in-time
Commitments and contingent liabilities (Note 14)	`CommitmentsAndContingencies`	-	USD	Point-in-time
Convertible preferred stock, $.01 par value; 3,000,000 shares authorized; no shares issued and outstanding at December 31, 2023 and 2022	`PreferredStockValue`	-	USD	Point-in-time
Convertible preferred stock, $.01 par value; 3,000,000 shares authorized; no shares issued and outstanding at December 31, 2023 and 2022	`PreferredStockValue`	-	USD	Point-in-time
Common stock, $.001 par value; 297,000,000 shares authorized; 55,883,377 and 47,200,695 shares issued and outstanding at December 31, 2023 and 2022, respectively	`CommonStockValue`	$56.00K	USD	Point-in-time
Common stock, $.001 par value; 297,000,000 shares authorized; 55,883,377 and 47,200,695 shares issued and outstanding at December 31, 2023 and 2022, respectively	`CommonStockValue`	$47.00K	USD	Point-in-time
Additional paid-in capital	`AdditionalPaidInCapitalCommonStock`	$1.58B	USD	Point-in-time
Additional paid-in capital	`AdditionalPaidInCapitalCommonStock`	$1.82B	USD	Point-in-time
Accumulated other comprehensive income	`AccumulatedOtherComprehensiveIncomeLossNetOfTax`	$1.26M	USD	Point-in-time
Accumulated other comprehensive income	`AccumulatedOtherComprehensiveIncomeLossNetOfTax`	$3.31M	USD	Point-in-time
Accumulated deficit	`RetainedEarningsAccumulatedDeficit`	$-1.40B	USD	Point-in-time
Accumulated deficit	`RetainedEarningsAccumulatedDeficit`	$-1.26B	USD	Point-in-time
Total stockholders' equity	`StockholdersEquity`	$326.20M	USD	Point-in-time
Total stockholders' equity	`StockholdersEquity`	$209.36M	USD	Point-in-time
Total stockholders' equity	`StockholdersEquity`	$419.48M	USD	Point-in-time
Total stockholders' equity	`StockholdersEquity`	$429.17M	USD	Point-in-time
Total liabilities and stockholders' equity	`LiabilitiesAndStockholdersEquity`	$465.63M	USD	Point-in-time
Total liabilities and stockholders' equity	`LiabilitiesAndStockholdersEquity`	$352.74M	USD	Point-in-time

Income Statement 51 line items

Line Item	Tag	Value	Unit	Period
Total revenues	`RevenueFromContractWithCustomerExcludingAssessedTax`	$4.65M	USD	Annual
Total revenues	`RevenueFromContractWithCustomerExcludingAssessedTax`	$2.36M	USD	Annual
Total revenues	`RevenueFromContractWithCustomerExcludingAssessedTax`	$6.88M	USD	Annual
Research and development	`ResearchAndDevelopmentExpense`	$82.26M	USD	Annual
Research and development	`ResearchAndDevelopmentExpense`	$118.01M	USD	Annual
Research and development	`ResearchAndDevelopmentExpense`	$53.31M	USD	Annual
General and administrative	`GeneralAndAdministrativeExpense`	$30.91M	USD	Annual
General and administrative	`GeneralAndAdministrativeExpense`	$20.49M	USD	Annual
General and administrative	`GeneralAndAdministrativeExpense`	$27.20M	USD	Annual
Intangible asset impairment	`ImpairmentOfIntangibleAssetsIndefinitelivedExcludingGoodwill`	$3.50M	USD	Annual
Gain on fair value remeasurement of contingent consideration	`BusinessCombinationContingentConsiderationArrangementsChangeInAmountOfContingentConsiderationAsset1`	$1.41M	USD	Annual
Gain on fair value remeasurement of contingent consideration	`BusinessCombinationContingentConsiderationArrangementsChangeInAmountOfContingentConsiderationAsset1`	$6.86M	USD	Annual
Litigation settlement related loss	`GainLossRelatedToLitigationSettlement`	$-15.00M	USD	Annual
Litigation settlement related loss	`GainLossRelatedToLitigationSettlement`	$-12.50M	USD	Annual
Total operating expenses	`CostsAndExpenses`	$161.43M	USD	Annual
Total operating expenses	`CostsAndExpenses`	$117.59M	USD	Annual
Total operating expenses	`CostsAndExpenses`	$75.89M	USD	Annual
Operating loss	`OperatingIncomeLoss`	$-115.23M	USD	Annual
Operating loss	`OperatingIncomeLoss`	$-71.24M	USD	Annual
Operating loss	`OperatingIncomeLoss`	$-154.54M	USD	Annual
Investment and other income, net	`InterestAndOtherIncome`	$13.11M	USD	Annual
Investment and other income, net	`InterestAndOtherIncome`	$505.00K	USD	Annual
Investment and other income, net	`InterestAndOtherIncome`	$2.91M	USD	Annual
Net loss before income tax benefit	`IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest`	$-112.33M	USD	Annual
Net loss before income tax benefit	`IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest`	$-141.43M	USD	Annual
Net loss before income tax benefit	`IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest`	$-70.74M	USD	Annual
Income tax benefit	`IncomeTaxExpenseBenefit`	$-227.00K	USD	Annual
Net loss	`NetIncomeLossAvailableToCommonStockholdersBasic`	$-112.33M	USD	Annual
Net loss	`NetIncomeLossAvailableToCommonStockholdersBasic`	$-141.43M	USD	Annual
Net loss	`NetIncomeLossAvailableToCommonStockholdersBasic`	$-70.51M	USD	Annual
Basic net loss per common share (in dollars per share)	`EarningsPerShareBasic`	$-1.64	USD	Annual
Basic net loss per common share (in dollars per share)	`EarningsPerShareBasic`	$-2.92	USD	Annual
Basic net loss per common share (in dollars per share)	`EarningsPerShareBasic`	$-2.40	USD	Annual
Diluted net loss per common share (in dollars per share)	`EarningsPerShareDiluted`	$-2.92	USD	Annual
Diluted net loss per common share (in dollars per share)	`EarningsPerShareDiluted`	$-1.64	USD	Annual
Diluted net loss per common share (in dollars per share)	`EarningsPerShareDiluted`	$-2.40	USD	Annual
Shares used in calculating basic net loss per share (in shares)	`WeightedAverageNumberOfSharesOutstandingBasic`	46,888.00	shares	Annual
Shares used in calculating basic net loss per share (in shares)	`WeightedAverageNumberOfSharesOutstandingBasic`	42,870.00	shares	Annual
Shares used in calculating basic net loss per share (in shares)	`WeightedAverageNumberOfSharesOutstandingBasic`	48,449.00	shares	Annual
Shares used in calculating diluted net loss per share (in shares)	`WeightedAverageNumberOfDilutedSharesOutstanding`	48,449.00	shares	Annual
Shares used in calculating diluted net loss per share (in shares)	`WeightedAverageNumberOfDilutedSharesOutstanding`	42,870.00	shares	Annual
Shares used in calculating diluted net loss per share (in shares)	`WeightedAverageNumberOfDilutedSharesOutstanding`	46,888.00	shares	Annual
Net loss	`NetIncomeLossAvailableToCommonStockholdersBasic`	$-112.33M	USD	Annual
Net loss	`NetIncomeLossAvailableToCommonStockholdersBasic`	$-141.43M	USD	Annual
Net loss	`NetIncomeLossAvailableToCommonStockholdersBasic`	$-70.51M	USD	Annual
Unrealized gain (loss) on marketable securities	`OtherComprehensiveIncomeUnrealizedHoldingGainLossOnSecuritiesArisingDuringPeriodNetOfTax`	$-634.00K	USD	Annual
Unrealized gain (loss) on marketable securities	`OtherComprehensiveIncomeUnrealizedHoldingGainLossOnSecuritiesArisingDuringPeriodNetOfTax`	$2.05M	USD	Annual
Unrealized gain (loss) on marketable securities	`OtherComprehensiveIncomeUnrealizedHoldingGainLossOnSecuritiesArisingDuringPeriodNetOfTax`	$-695.00K	USD	Annual
Comprehensive loss	`ComprehensiveIncomeNetOfTax`	$-139.38M	USD	Annual
Comprehensive loss	`ComprehensiveIncomeNetOfTax`	$-71.21M	USD	Annual
Comprehensive loss	`ComprehensiveIncomeNetOfTax`	$-112.96M	USD	Annual

Cash Flow Statement 71 line items

Line Item	Tag	Value	Unit	Period
Net loss	`NetIncomeLossAvailableToCommonStockholdersBasic`	$-112.33M	USD	Annual
Net loss	`NetIncomeLossAvailableToCommonStockholdersBasic`	$-141.43M	USD	Annual
Net loss	`NetIncomeLossAvailableToCommonStockholdersBasic`	$-70.51M	USD	Annual
Depreciation and amortization	`DepreciationDepletionAndAmortization`	$3.07M	USD	Annual
Depreciation and amortization	`DepreciationDepletionAndAmortization`	$3.01M	USD	Annual
Depreciation and amortization	`DepreciationDepletionAndAmortization`	$2.90M	USD	Annual
Amortization and premium of marketable securities, net	`AccretionAmortizationOfDiscountsAndPremiumsInvestments`	$3.21M	USD	Annual
Amortization and premium of marketable securities, net	`AccretionAmortizationOfDiscountsAndPremiumsInvestments`	$-844.00K	USD	Annual
Amortization and premium of marketable securities, net	`AccretionAmortizationOfDiscountsAndPremiumsInvestments`	$6.22M	USD	Annual
Loss (gain) on sale or disposal of assets	`GainLossOnSaleOfPropertyPlantEquipment`	$-2.00K	USD	Annual
Loss (gain) on sale or disposal of assets	`GainLossOnSaleOfPropertyPlantEquipment`	$24.00K	USD	Annual
Intangible asset impairment	`ImpairmentOfIntangibleAssetsIndefinitelivedExcludingGoodwill`	$3.50M	USD	Annual
Gain on fair value remeasurement of contingent consideration	`BusinessCombinationContingentConsiderationArrangementsChangeInAmountOfContingentConsiderationAsset1`	$1.41M	USD	Annual
Gain on fair value remeasurement of contingent consideration	`BusinessCombinationContingentConsiderationArrangementsChangeInAmountOfContingentConsiderationAsset1`	$6.86M	USD	Annual
Non-cash income tax benefit	`IncomeTaxExpenseBenefit`	$-227.00K	USD	Annual
Stock-based compensation expense	`ShareBasedCompensation`	$8.95M	USD	Annual
Stock-based compensation expense	`ShareBasedCompensation`	$15.61M	USD	Annual
Stock-based compensation expense	`ShareBasedCompensation`	$23.89M	USD	Annual
Accounts and other receivables	`IncreaseDecreaseInAccountsAndOtherReceivables`	$175.00K	USD	Annual
Accounts and other receivables	`IncreaseDecreaseInAccountsAndOtherReceivables`	$2.28M	USD	Annual
Accounts and other receivables	`IncreaseDecreaseInAccountsAndOtherReceivables`	$-1.57M	USD	Annual
Prepaid and other current assets	`IncreaseDecreaseInPrepaidDeferredExpenseAndOtherAssets`	$9.57M	USD	Annual
Prepaid and other current assets	`IncreaseDecreaseInPrepaidDeferredExpenseAndOtherAssets`	$-5.90M	USD	Annual
Prepaid and other current assets	`IncreaseDecreaseInPrepaidDeferredExpenseAndOtherAssets`	$1.87M	USD	Annual
Other assets	`IncreaseDecreaseInOtherOperatingAssets`	$3.00K	USD	Annual
Other assets	`IncreaseDecreaseInOtherOperatingAssets`	$5.00K	USD	Annual
Accounts payable and accrued expenses	`IncreaseDecreaseInAccountsPayableAndAccruedLiabilities`	$3.65M	USD	Annual
Accounts payable and accrued expenses	`IncreaseDecreaseInAccountsPayableAndAccruedLiabilities`	$9.38M	USD	Annual
Accounts payable and accrued expenses	`IncreaseDecreaseInAccountsPayableAndAccruedLiabilities`	$3.12M	USD	Annual
Other liabilities	`IncreaseDecreaseInOtherOperatingLiabilities`	$462.00K	USD	Annual
Other liabilities	`IncreaseDecreaseInOtherOperatingLiabilities`	$2.73M	USD	Annual
Other liabilities	`IncreaseDecreaseInOtherOperatingLiabilities`	$-4.41M	USD	Annual
Net cash used in operating activities	`NetCashProvidedByUsedInOperatingActivities`	$-107.29M	USD	Annual
Net cash used in operating activities	`NetCashProvidedByUsedInOperatingActivities`	$-103.73M	USD	Annual
Net cash used in operating activities	`NetCashProvidedByUsedInOperatingActivities`	$-60.91M	USD	Annual
Sales and maturities of marketable securities	`ProceedsFromSaleAndMaturityOfMarketableSecurities`	$280.67M	USD	Annual
Sales and maturities of marketable securities	`ProceedsFromSaleAndMaturityOfMarketableSecurities`	$320.60M	USD	Annual
Sales and maturities of marketable securities	`ProceedsFromSaleAndMaturityOfMarketableSecurities`	$174.95M	USD	Annual
Purchases of marketable securities	`PaymentsToAcquireMarketableSecurities`	$424.56M	USD	Annual
Purchases of marketable securities	`PaymentsToAcquireMarketableSecurities`	$389.88M	USD	Annual
Purchases of marketable securities	`PaymentsToAcquireMarketableSecurities`	$188.97M	USD	Annual
Acquisition of property and equipment	`PaymentsToAcquirePropertyPlantAndEquipment`	$1.82M	USD	Annual
Acquisition of property and equipment	`PaymentsToAcquirePropertyPlantAndEquipment`	$1.83M	USD	Annual
Acquisition of property and equipment	`PaymentsToAcquirePropertyPlantAndEquipment`	$1.25M	USD	Annual
Proceeds from sale or disposal of assets	`ProceedsFromSaleOfProductiveAssets`	$69.00K	USD	Annual
Proceeds from sale or disposal of assets	`ProceedsFromSaleOfProductiveAssets`	$27.00K	USD	Annual
Net cash (used in) provided by investing activities	`NetCashProvidedByUsedInInvestingActivities`	$-216.16M	USD	Annual
Net cash (used in) provided by investing activities	`NetCashProvidedByUsedInInvestingActivities`	$89.94M	USD	Annual
Net cash (used in) provided by investing activities	`NetCashProvidedByUsedInInvestingActivities`	$-105.78M	USD	Annual
Net proceeds from stock issuances	`ProceedsFromIssuanceOfCommonStock`	$269.89M	USD	Annual
Net proceeds from stock issuances	`ProceedsFromIssuanceOfCommonStock`	$216.22M	USD	Annual
Proceeds from issuance of stock from employee benefit plans	`ProceedsFromStockPlans`	$4.08M	USD	Annual
Proceeds from issuance of stock from employee benefit plans	`ProceedsFromStockPlans`	$2.24M	USD	Annual
Proceeds from issuance of stock from employee benefit plans	`ProceedsFromStockPlans`	$2.48M	USD	Annual
Net cash provided by financing activities	`NetCashProvidedByUsedInFinancingActivities`	$218.46M	USD	Annual
Net cash provided by financing activities	`NetCashProvidedByUsedInFinancingActivities`	$4.08M	USD	Annual
Net cash provided by financing activities	`NetCashProvidedByUsedInFinancingActivities`	$272.37M	USD	Annual
Net increase (decrease) in cash and cash equivalents	`CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseIncludingExchangeRateEffect`	$-4.69M	USD	Annual
Net increase (decrease) in cash and cash equivalents	`CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseIncludingExchangeRateEffect`	$5.38M	USD	Annual
Net increase (decrease) in cash and cash equivalents	`CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseIncludingExchangeRateEffect`	$-9.71M	USD	Annual
Cash and cash equivalents at beginning of period	`CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents`	$29.43M	USD	Point-in-time
Cash and cash equivalents at beginning of period	`CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents`	$34.81M	USD	Point-in-time
Cash and cash equivalents at beginning of period	`CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents`	$43.84M	USD	Point-in-time
Cash and cash equivalents at beginning of period	`CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents`	$39.14M	USD	Point-in-time
Cash and cash equivalents at end of period	`CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents`	$29.43M	USD	Point-in-time
Cash and cash equivalents at end of period	`CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents`	$34.81M	USD	Point-in-time
Cash and cash equivalents at end of period	`CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents`	$43.84M	USD	Point-in-time
Cash and cash equivalents at end of period	`CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents`	$39.14M	USD	Point-in-time
Accrued construction in progress	`ConstructionInProgressExpendituresIncurredButNotYetPaid`	$289.00K	USD	Annual
Accrued construction in progress	`ConstructionInProgressExpendituresIncurredButNotYetPaid`	$77.00K	USD	Annual
Accrued construction in progress	`ConstructionInProgressExpendituresIncurredButNotYetPaid`	$113.00K	USD	Annual

Stockholders Equity 26 line items

Line Item	Tag	Value	Unit	Period
Balance, beginning	`StockholdersEquity`	$326.20M	USD	Point-in-time
Balance, beginning	`StockholdersEquity`	$209.36M	USD	Point-in-time
Balance, beginning	`StockholdersEquity`	$419.48M	USD	Point-in-time
Balance, beginning	`StockholdersEquity`	$429.17M	USD	Point-in-time
Balance, beginning (in shares)	`CommonStockSharesIssued`	47.20M	shares	Point-in-time
Balance, beginning (in shares)	`CommonStockSharesIssued`	55.88M	shares	Point-in-time
Shares issued under stock option and employee stock purchase plans	`StockIssuedDuringPeriodValueEmployeeStockPurchasePlan`	$4.08M	USD	Annual
Shares issued under stock option and employee stock purchase plans	`StockIssuedDuringPeriodValueEmployeeStockPurchasePlan`	$2.48M	USD	Annual
Shares issued under stock option and employee stock purchase plans	`StockIssuedDuringPeriodValueEmployeeStockPurchasePlan`	$2.24M	USD	Annual
Shares issued in underwritten offering, net	`StockIssuedDuringPeriodValueNewIssues`	$216.22M	USD	Annual
Shares issued in underwritten offering, net	`StockIssuedDuringPeriodValueNewIssues`	$269.89M	USD	Annual
Stock-based compensation	`AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue`	$23.89M	USD	Annual
Stock-based compensation	`AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue`	$15.61M	USD	Annual
Stock-based compensation	`AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue`	$8.95M	USD	Annual
Unrealized gain (loss) on marketable securities	`OtherComprehensiveIncomeUnrealizedHoldingGainLossOnSecuritiesArisingDuringPeriodNetOfTax`	$-634.00K	USD	Annual
Unrealized gain (loss) on marketable securities	`OtherComprehensiveIncomeUnrealizedHoldingGainLossOnSecuritiesArisingDuringPeriodNetOfTax`	$2.05M	USD	Annual
Unrealized gain (loss) on marketable securities	`OtherComprehensiveIncomeUnrealizedHoldingGainLossOnSecuritiesArisingDuringPeriodNetOfTax`	$-695.00K	USD	Annual
Net loss	`NetIncomeLossAvailableToCommonStockholdersBasic`	$-112.33M	USD	Annual
Net loss	`NetIncomeLossAvailableToCommonStockholdersBasic`	$-141.43M	USD	Annual
Net loss	`NetIncomeLossAvailableToCommonStockholdersBasic`	$-70.51M	USD	Annual
Balance, ending	`StockholdersEquity`	$326.20M	USD	Point-in-time
Balance, ending	`StockholdersEquity`	$209.36M	USD	Point-in-time
Balance, ending	`StockholdersEquity`	$419.48M	USD	Point-in-time
Balance, ending	`StockholdersEquity`	$429.17M	USD	Point-in-time
Balance, ending (in shares)	`CommonStockSharesIssued`	47.20M	shares	Point-in-time
Balance, ending (in shares)	`CommonStockSharesIssued`	55.88M	shares	Point-in-time

Data is extracted from SEC EDGAR XBRL filings. Values shown are as reported in the filing.