10-K Filing

IOVANCE BIOTHERAPEUTICS, INC. CIK: 1425205 FY 2018

Filing Information

Form Type	10-K
Accession Number	`0001144204-19-010702`
Period End Date	20181231
Filing Date	20190228
Fiscal Year	2018
Fiscal Period	FY
XBRL Instance	iova-20181231.xml

Filing Contents

This filing contains the following financial statements:

Balance Sheet 52 Income Statement 65 Cash Flow Statement 92 Stockholders Equity 49 Comprehensive Income 17

Balance Sheet 52 line items

Line Item	Tag	Value	Unit	Period
Cash and cash equivalents	`CashAndCashEquivalentsAtCarryingValue`	$33.59M	USD	Point-in-time
Cash and cash equivalents	`CashAndCashEquivalentsAtCarryingValue`	$106.72M	USD	Point-in-time
Cash and cash equivalents	`CashAndCashEquivalentsAtCarryingValue`	$145.37M	USD	Point-in-time
Cash and cash equivalents	`CashAndCashEquivalentsAtCarryingValue`	$82.15M	USD	Point-in-time
Short-term investments	`AvailableForSaleSecuritiesCurrent`	-	USD	Point-in-time
Short-term investments	`AvailableForSaleSecuritiesCurrent`	$386.37M	USD	Point-in-time
Prepaid expenses and other assets	`PrepaidExpenseAndOtherAssetsCurrent`	$6.85M	USD	Point-in-time
Prepaid expenses and other assets	`PrepaidExpenseAndOtherAssetsCurrent`	$3.92M	USD	Point-in-time
Total Current Assets	`AssetsCurrent`	$149.29M	USD	Point-in-time
Common Stock, Par or Stated Value Per Share	`CommonStockParOrStatedValuePerShare`	-	USD	Point-in-time
Total Current Assets	`AssetsCurrent`	$475.37M	USD	Point-in-time
Common Stock, Par or Stated Value Per Share	`CommonStockParOrStatedValuePerShare`	-	USD	Point-in-time
Property and equipment, net	`PropertyPlantAndEquipmentNet`	$2.45M	USD	Point-in-time
Common Stock, Shares Authorized	`CommonStockSharesAuthorized`	150.00M	shares	Point-in-time
Property and equipment, net	`PropertyPlantAndEquipmentNet`	$2.68M	USD	Point-in-time
Common Stock, Shares Authorized	`CommonStockSharesAuthorized`	150.00M	shares	Point-in-time
Common Stock, Shares, Issued	`CommonStockSharesIssued`	73.16M	shares	Point-in-time
Long-term assets	`OtherAssetsNoncurrent`	$3.63M	USD	Point-in-time
Common Stock, Shares, Issued	`CommonStockSharesIssued`	123.42M	shares	Point-in-time
Long-term assets	`OtherAssetsNoncurrent`	$2.76M	USD	Point-in-time
Common Stock, Shares, Outstanding	`CommonStockSharesOutstanding`	73.16M	shares	Point-in-time
Total Assets	`Assets`	$480.82M	USD	Point-in-time
Total Assets	`Assets`	$155.37M	USD	Point-in-time
Common Stock, Shares, Outstanding	`CommonStockSharesOutstanding`	123.42M	shares	Point-in-time
Accounts payable	`AccountsPayableCurrent`	$2.74M	USD	Point-in-time
Accounts payable	`AccountsPayableCurrent`	$1.23M	USD	Point-in-time
Accrued expenses	`AccruedLiabilitiesCurrent`	$11.66M	USD	Point-in-time
Accrued expenses	`AccruedLiabilitiesCurrent`	$8.36M	USD	Point-in-time
Total Current Liabilities	`LiabilitiesCurrent`	$9.60M	USD	Point-in-time
Total Current Liabilities	`LiabilitiesCurrent`	$14.40M	USD	Point-in-time
Deferred rent	`DeferredRentCreditNoncurrent`	$297.00K	USD	Point-in-time
Deferred rent	`DeferredRentCreditNoncurrent`	$230.00K	USD	Point-in-time
Total Non-Current Liabilities	`LiabilitiesNoncurrent`	$230.00K	USD	Point-in-time
Total Non-Current Liabilities	`LiabilitiesNoncurrent`	$297.00K	USD	Point-in-time
Total Liabilities	`Liabilities`	$14.63M	USD	Point-in-time
Total Liabilities	`Liabilities`	$9.89M	USD	Point-in-time
Commitments and contingencies (Note 11)	`CommitmentsAndContingencies`	-	USD	Point-in-time
Commitments and contingencies (Note 11)	`CommitmentsAndContingencies`	-	USD	Point-in-time
Common stock, $0.000041666 par value; 150,000,000 shares authorized, 123,415,576 and 73,164,914 shares issued and outstanding as of December 31, 2018 and December 31, 2017, respectively	`CommonStockValue`	$3.00K	USD	Point-in-time
Common stock, $0.000041666 par value; 150,000,000 shares authorized, 123,415,576 and 73,164,914 shares issued and outstanding as of December 31, 2018 and December 31, 2017, respectively	`CommonStockValue`	$5.00K	USD	Point-in-time
Accumulated other comprehensive loss	`AccumulatedOtherComprehensiveIncomeLossNetOfTax`	-	USD	Point-in-time
Accumulated other comprehensive loss	`AccumulatedOtherComprehensiveIncomeLossNetOfTax`	$-42.00K	USD	Point-in-time
Additional paid-in capital	`AdditionalPaidInCapital`	$394.65M	USD	Point-in-time
Additional paid-in capital	`AdditionalPaidInCapital`	$838.98M	USD	Point-in-time
Accumulated deficit	`RetainedEarningsAccumulatedDeficit`	$-249.18M	USD	Point-in-time
Accumulated deficit	`RetainedEarningsAccumulatedDeficit`	$-372.76M	USD	Point-in-time
Total Stockholders' Equity	`StockholdersEquity`	$145.48M	USD	Point-in-time
Total Stockholders' Equity	`StockholdersEquity`	$466.19M	USD	Point-in-time
Total Stockholders' Equity	`StockholdersEquity`	$104.02M	USD	Point-in-time
Total Stockholders' Equity	`StockholdersEquity`	$166.92M	USD	Point-in-time
Total Liabilities and Stockholders' Equity	`LiabilitiesAndStockholdersEquity`	$155.37M	USD	Point-in-time
Total Liabilities and Stockholders' Equity	`LiabilitiesAndStockholdersEquity`	$480.82M	USD	Point-in-time

Income Statement 65 line items

Line Item	Tag	Value	Unit	Period
Revenues	`Revenues`	-	USD	1 Quarter
Revenues	`Revenues`	-	USD	1 Quarter
Revenues	`Revenues`	-	USD	Annual
Revenues	`Revenues`	-	USD	1 Quarter
Revenues	`Revenues`	-	USD	Annual
Revenues	`Revenues`	-	USD	Annual
Revenues	`Revenues`	-	USD	1 Quarter
Revenues	`Revenues`	-	USD	1 Quarter
Revenues	`Revenues`	-	USD	1 Quarter
Revenues	`Revenues`	-	USD	1 Quarter
Revenues	`Revenues`	-	USD	1 Quarter
Research and development expenses	`ResearchAndDevelopmentExpense`	$26.94M	USD	Annual
Research and development expenses	`ResearchAndDevelopmentExpense`	$71.61M	USD	Annual
Research and development expenses	`ResearchAndDevelopmentExpense`	$99.83M	USD	Annual
General and administrative expenses	`GeneralAndAdministrativeExpense`	$21.26M	USD	Annual
General and administrative expenses	`GeneralAndAdministrativeExpense`	$26.70M	USD	Annual
General and administrative expenses	`GeneralAndAdministrativeExpense`	$28.43M	USD	Annual
Total costs and expenses	`OperatingExpenses`	$53.64M	USD	Annual
Total costs and expenses	`OperatingExpenses`	$92.88M	USD	Annual
Total costs and expenses	`OperatingExpenses`	$128.26M	USD	Annual
Loss from operations	`OperatingIncomeLoss`	$-53.64M	USD	Annual
Loss from operations	`OperatingIncomeLoss`	$-92.88M	USD	Annual
Loss from operations	`OperatingIncomeLoss`	$-128.26M	USD	Annual
Interest income, net	`InvestmentIncomeInterest`	$813.00K	USD	Annual
Interest income, net	`InvestmentIncomeInterest`	$4.68M	USD	Annual
Interest income, net	`InvestmentIncomeInterest`	$745.00K	USD	Annual
Net Loss	`NetIncomeLoss`	$-32.58M	USD	1 Quarter
Net Loss	`NetIncomeLoss`	$-25.85M	USD	1 Quarter
Net Loss	`NetIncomeLoss`	$-22.15M	USD	1 Quarter
Net Loss	`NetIncomeLoss`	$-30.66M	USD	1 Quarter
Net Loss	`NetIncomeLoss`	$-52.89M	USD	Annual
Net Loss	`NetIncomeLoss`	$-20.68M	USD	1 Quarter
Net Loss	`NetIncomeLoss`	$-26.52M	USD	1 Quarter
Net Loss	`NetIncomeLoss`	$-123.58M	USD	Annual
Net Loss	`NetIncomeLoss`	$-23.38M	USD	1 Quarter
Net Loss	`NetIncomeLoss`	$-33.83M	USD	1 Quarter
Net Loss	`NetIncomeLoss`	$-92.06M	USD	Annual
Deemed dividend related to beneficial conversion feature of convertible preferred stock	`OtherPreferredStockDividendsAndAdjustments`	$49.45M	USD	Annual
Deemed dividend related to beneficial conversion feature of convertible preferred stock	`OtherPreferredStockDividendsAndAdjustments`	-	USD	Annual
Deemed dividend related to beneficial conversion feature of convertible preferred stock	`OtherPreferredStockDividendsAndAdjustments`	-	USD	Annual
Net Loss Attributable to Common Stockholders	`NetIncomeLossAvailableToCommonStockholdersBasic`	$-92.06M	USD	Annual
Net Loss Attributable to Common Stockholders	`NetIncomeLossAvailableToCommonStockholdersBasic`	$-123.58M	USD	Annual
Net Loss Attributable to Common Stockholders	`NetIncomeLossAvailableToCommonStockholdersBasic`	$-102.35M	USD	Annual
Net Loss Per Common Share, Basic and Diluted	`EarningsPerShareBasicAndDiluted`	$-0.31	USD	1 Quarter
Net Loss Per Common Share, Basic and Diluted	`EarningsPerShareBasicAndDiluted`	$-0.27	USD	1 Quarter
Net Loss Per Common Share, Basic and Diluted	`EarningsPerShareBasicAndDiluted`	$-1.27	USD	Annual
Net Loss Per Common Share, Basic and Diluted	`EarningsPerShareBasicAndDiluted`	$-1.85	USD	Annual
Net Loss Per Common Share, Basic and Diluted	`EarningsPerShareBasicAndDiluted`	$-0.35	USD	1 Quarter
Net Loss Per Common Share, Basic and Diluted	`EarningsPerShareBasicAndDiluted`	$-0.36	USD	1 Quarter
Net Loss Per Common Share, Basic and Diluted	`EarningsPerShareBasicAndDiluted`	$-1.41	USD	Annual
Net Loss Per Common Share, Basic and Diluted	`EarningsPerShareBasicAndDiluted`	$-0.37	USD	1 Quarter
Net Loss Per Common Share, Basic and Diluted	`EarningsPerShareBasicAndDiluted`	$-0.33	USD	1 Quarter
Net Loss Per Common Share, Basic and Diluted	`EarningsPerShareBasicAndDiluted`	$-0.34	USD	1 Quarter
Net Loss Per Common Share, Basic and Diluted	`EarningsPerShareBasicAndDiluted`	$-0.36	USD	1 Quarter
Weighted-Average Common Share Outstanding, Basic and Diluted	`WeightedAverageNumberOfShareOutstandingBasicAndDiluted`	55,268.00	shares	Annual
Weighted-Average Common Share Outstanding, Basic and Diluted	`WeightedAverageNumberOfShareOutstandingBasicAndDiluted`	119,085.00	shares	1 Quarter
Weighted-Average Common Share Outstanding, Basic and Diluted	`WeightedAverageNumberOfShareOutstandingBasicAndDiluted`	62,457.00	shares	1 Quarter
Weighted-Average Common Share Outstanding, Basic and Diluted	`WeightedAverageNumberOfShareOutstandingBasicAndDiluted`	97,277.00	shares	Annual
Weighted-Average Common Share Outstanding, Basic and Diluted	`WeightedAverageNumberOfShareOutstandingBasicAndDiluted`	65,242.00	shares	Annual
Weighted-Average Common Share Outstanding, Basic and Diluted	`WeightedAverageNumberOfShareOutstandingBasicAndDiluted`	72,794.00	shares	1 Quarter
Weighted-Average Common Share Outstanding, Basic and Diluted	`WeightedAverageNumberOfShareOutstandingBasicAndDiluted`	95,077.00	shares	1 Quarter
Weighted-Average Common Share Outstanding, Basic and Diluted	`WeightedAverageNumberOfShareOutstandingBasicAndDiluted`	63,332.00	shares	1 Quarter
Weighted-Average Common Share Outstanding, Basic and Diluted	`WeightedAverageNumberOfShareOutstandingBasicAndDiluted`	84,350.00	shares	1 Quarter
Weighted-Average Common Share Outstanding, Basic and Diluted	`WeightedAverageNumberOfShareOutstandingBasicAndDiluted`	90,236.00	shares	1 Quarter
Weighted-Average Common Share Outstanding, Basic and Diluted	`WeightedAverageNumberOfShareOutstandingBasicAndDiluted`	62,286.00	shares	1 Quarter

Cash Flow Statement 92 line items

Line Item	Tag	Value	Unit	Period
Net loss	`NetIncomeLoss`	$-32.58M	USD	1 Quarter
Net loss	`NetIncomeLoss`	$-25.85M	USD	1 Quarter
Net loss	`NetIncomeLoss`	$-22.15M	USD	1 Quarter
Net loss	`NetIncomeLoss`	$-30.66M	USD	1 Quarter
Net loss	`NetIncomeLoss`	$-52.89M	USD	Annual
Net loss	`NetIncomeLoss`	$-20.68M	USD	1 Quarter
Net loss	`NetIncomeLoss`	$-26.52M	USD	1 Quarter
Net loss	`NetIncomeLoss`	$-123.58M	USD	Annual
Net loss	`NetIncomeLoss`	$-23.38M	USD	1 Quarter
Net loss	`NetIncomeLoss`	$-33.83M	USD	1 Quarter
Net loss	`NetIncomeLoss`	$-92.06M	USD	Annual
Depreciation and amortization	`DepreciationAndAmortization`	$952.00K	USD	Annual
Depreciation and amortization	`DepreciationAndAmortization`	$956.00K	USD	Annual
Depreciation and amortization	`DepreciationAndAmortization`	$978.00K	USD	Annual
Loss on disposal of assets	`GainLossOnDispositionOfAssets`	-	USD	Annual
Loss on disposal of assets	`GainLossOnDispositionOfAssets`	$-9.00K	USD	Annual
Loss on disposal of assets	`GainLossOnDispositionOfAssets`	-	USD	Annual
Accretion (amortization) of discounts and premiums on investments	`AmortizationOfDebtDiscountPremium`	$-1.33M	USD	Annual
Accretion (amortization) of discounts and premiums on investments	`AmortizationOfDebtDiscountPremium`	$19.00K	USD	Annual
Accretion (amortization) of discounts and premiums on investments	`AmortizationOfDebtDiscountPremium`	$-74.00K	USD	Annual
Stock-based compensation expense	`ShareBasedCompensation`	$11.97M	USD	Annual
Stock-based compensation expense	`ShareBasedCompensation`	$18.90M	USD	Annual
Stock-based compensation expense	`ShareBasedCompensation`	$20.03M	USD	Annual
Prepaid expenses and other assets	`IncreaseDecreaseInPrepaidDeferredExpenseAndOtherAssets`	$4.51M	USD	Annual
Prepaid expenses and other assets	`IncreaseDecreaseInPrepaidDeferredExpenseAndOtherAssets`	$2.77M	USD	Annual
Prepaid expenses and other assets	`IncreaseDecreaseInPrepaidDeferredExpenseAndOtherAssets`	$2.06M	USD	Annual
Accounts payable	`IncreaseDecreaseInAccountsPayable`	$369.00K	USD	Annual
Accounts payable	`IncreaseDecreaseInAccountsPayable`	$1.51M	USD	Annual
Accounts payable	`IncreaseDecreaseInAccountsPayable`	$-250.00K	USD	Annual
Accrued expenses	`IncreaseDecreaseInAccruedLiabilities`	$3.43M	USD	Annual
Accrued expenses	`IncreaseDecreaseInAccruedLiabilities`	$3.23M	USD	Annual
Accrued expenses	`IncreaseDecreaseInAccruedLiabilities`	$4.55M	USD	Annual
Net cash used in operating activities	`NetCashProvidedByUsedInOperatingActivities`	$-32.67M	USD	Annual
Net cash used in operating activities	`NetCashProvidedByUsedInOperatingActivities`	$-101.25M	USD	Annual
Net cash used in operating activities	`NetCashProvidedByUsedInOperatingActivities`	$-78.71M	USD	Annual
Maturities of short-term investments	`ProceedsFromSaleAndMaturityOfAvailableForSaleSecurities`	$41.00M	USD	Annual
Maturities of short-term investments	`ProceedsFromSaleAndMaturityOfAvailableForSaleSecurities`	$59.70M	USD	Annual
Maturities of short-term investments	`ProceedsFromSaleAndMaturityOfAvailableForSaleSecurities`	$120.66M	USD	Annual
Purchase of short-term investments	`PaymentsToAcquireAvailableForSaleSecurities`	$426.08M	USD	Annual
Purchase of short-term investments	`PaymentsToAcquireAvailableForSaleSecurities`	-	USD	Annual
Purchase of short-term investments	`PaymentsToAcquireAvailableForSaleSecurities`	$110.25M	USD	Annual
Purchase of property and equipment	`PaymentsToAcquirePropertyPlantAndEquipment`	$1.52M	USD	Annual
Purchase of property and equipment	`PaymentsToAcquirePropertyPlantAndEquipment`	$1.03M	USD	Annual
Purchase of property and equipment	`PaymentsToAcquirePropertyPlantAndEquipment`	$1.20M	USD	Annual
Net cash (used in) provided by investing activities	`NetCashProvidedByUsedInInvestingActivities`	$-386.28M	USD	Annual
Net cash (used in) provided by investing activities	`NetCashProvidedByUsedInInvestingActivities`	$58.68M	USD	Annual
Net cash (used in) provided by investing activities	`NetCashProvidedByUsedInInvestingActivities`	$8.89M	USD	Annual
Tax payments related to shares withheld for vested restricted stock awards	`PaymentsRelatedToTaxWithholdingForShareBasedCompensation`	$1.25M	USD	Annual
Tax payments related to shares withheld for vested restricted stock awards	`PaymentsRelatedToTaxWithholdingForShareBasedCompensation`	$223.00K	USD	Annual
Tax payments related to shares withheld for vested restricted stock awards	`PaymentsRelatedToTaxWithholdingForShareBasedCompensation`	$642.00K	USD	Annual
Proceeds from the issuance of common stock upon exercise of warrants	`ProceedsFromWarrantExercises`	$15.75M	USD	Annual
Proceeds from the issuance of common stock upon exercise of warrants	`ProceedsFromWarrantExercises`	$662.00K	USD	Annual
Proceeds from the issuance of common stock upon exercise of warrants	`ProceedsFromWarrantExercises`	$1.24M	USD	Annual
Proceeds from the issuance of common stock upon exercise of options	`ProceedsFromStockOptionsExercised`	$9.96M	USD	Annual
Proceeds from the issuance of common stock upon exercise of options	`ProceedsFromStockOptionsExercised`	$5.62M	USD	Annual
Proceeds from the issuance of common stock upon exercise of options	`ProceedsFromStockOptionsExercised`	$626.00K	USD	Annual
Proceeds from the issuance of preferred stock and common stock, net	`ProceedsFromIssuanceOfCommonStock`	$53.66M	USD	Annual
Proceeds from the issuance of preferred stock and common stock, net	`ProceedsFromIssuanceOfCommonStock`	$236.70M	USD	Point-in-time
Proceeds from the issuance of preferred stock and common stock, net	`ProceedsFromIssuanceOfCommonStock`	$95.69M	USD	Annual
Proceeds from the issuance of preferred stock and common stock, net	`ProceedsFromIssuanceOfCommonStock`	$398.82M	USD	Annual
Net cash provided by financing activities	`NetCashProvidedByUsedInFinancingActivities`	$424.31M	USD	Annual
Net cash provided by financing activities	`NetCashProvidedByUsedInFinancingActivities`	$96.90M	USD	Annual
Net cash provided by financing activities	`NetCashProvidedByUsedInFinancingActivities`	$58.69M	USD	Annual
Net (decrease) increase in cash and cash equivalents	`CashAndCashEquivalentsPeriodIncreaseDecrease`	$-63.22M	USD	Annual
Net (decrease) increase in cash and cash equivalents	`CashAndCashEquivalentsPeriodIncreaseDecrease`	$38.66M	USD	Annual
Net (decrease) increase in cash and cash equivalents	`CashAndCashEquivalentsPeriodIncreaseDecrease`	$73.13M	USD	Annual
Cash and Cash Equivalents, Beginning of Period	`CashAndCashEquivalentsAtCarryingValue`	$33.59M	USD	Point-in-time
Cash and Cash Equivalents, Beginning of Period	`CashAndCashEquivalentsAtCarryingValue`	$106.72M	USD	Point-in-time
Cash and Cash Equivalents, Beginning of Period	`CashAndCashEquivalentsAtCarryingValue`	$145.37M	USD	Point-in-time
Cash and Cash Equivalents, Beginning of Period	`CashAndCashEquivalentsAtCarryingValue`	$82.15M	USD	Point-in-time
Cash and Cash Equivalents, End of Period	`CashAndCashEquivalentsAtCarryingValue`	$33.59M	USD	Point-in-time
Cash and Cash Equivalents, End of Period	`CashAndCashEquivalentsAtCarryingValue`	$106.72M	USD	Point-in-time
Cash and Cash Equivalents, End of Period	`CashAndCashEquivalentsAtCarryingValue`	$145.37M	USD	Point-in-time
Cash and Cash Equivalents, End of Period	`CashAndCashEquivalentsAtCarryingValue`	$82.15M	USD	Point-in-time
Cash paid for income taxes	`IncomeTaxesPaidNet`	-	USD	Annual
Cash paid for income taxes	`IncomeTaxesPaidNet`	-	USD	Annual
Cash paid for income taxes	`IncomeTaxesPaidNet`	-	USD	Annual
Interest paid	`InterestPaidNet`	-	USD	Annual
Interest paid	`InterestPaidNet`	-	USD	Annual
Interest paid	`InterestPaidNet`	-	USD	Annual
Net unrealized loss on short-term investments	`UnrealizedGainLossOnShorttermInvestments`	$-29.00K	USD	Annual
Net unrealized loss on short-term investments	`UnrealizedGainLossOnShorttermInvestments`	$-19.00K	USD	Annual
Net unrealized loss on short-term investments	`UnrealizedGainLossOnShorttermInvestments`	$-42.00K	USD	Annual
Acquisitions of property and equipment included in accounts payable	`LeaseholdImprovementsPaidByLandlord`	-	USD	Annual
Acquisitions of property and equipment included in accounts payable	`LeaseholdImprovementsPaidByLandlord`	-	USD	Annual
Acquisitions of property and equipment included in accounts payable	`LeaseholdImprovementsPaidByLandlord`	$155.00K	USD	Annual
Offering costs under accounts payable and accrued expenses	`OfferingCostsUnderAccountsPayableAndAccruedExpenses`	-	USD	Annual
Offering costs under accounts payable and accrued expenses	`OfferingCostsUnderAccountsPayableAndAccruedExpenses`	$49.45M	USD	Annual
Offering costs under accounts payable and accrued expenses	`OfferingCostsUnderAccountsPayableAndAccruedExpenses`	-	USD	Annual
Conversion of convertible preferred stock to common stock	`ConversionOfStockAmountConverted1`	$1.00K	USD	Annual
Conversion of convertible preferred stock to common stock	`ConversionOfStockAmountConverted1`	$3.00K	USD	Annual
Conversion of convertible preferred stock to common stock	`ConversionOfStockAmountConverted1`	$1.00K	USD	Annual

Stockholders Equity 49 line items

Line Item	Tag	Value	Unit	Period
Beginning Balance	`StockholdersEquity`	$145.48M	USD	Point-in-time
Beginning Balance	`StockholdersEquity`	$466.19M	USD	Point-in-time
Beginning Balance	`StockholdersEquity`	$104.02M	USD	Point-in-time
Beginning Balance	`StockholdersEquity`	$166.92M	USD	Point-in-time
Stock-based compensation expense	`AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue`	$20.03M	USD	Annual
Stock-based compensation expense	`AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue`	$18.90M	USD	Annual
Stock-based compensation expense	`AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue`	$11.97M	USD	Annual
Tax payments related to shares witheld for vested restricted stock awards	`AdjustmentToAdditionalPaidInCapitalIncomeTaxEffectFromShareBasedCompensationNet`	$223.00K	USD	Annual
Tax payments related to shares witheld for vested restricted stock awards	`AdjustmentToAdditionalPaidInCapitalIncomeTaxEffectFromShareBasedCompensationNet`	$642.00K	USD	Annual
Tax payments related to shares witheld for vested restricted stock awards	`AdjustmentToAdditionalPaidInCapitalIncomeTaxEffectFromShareBasedCompensationNet`	$1.25M	USD	Annual
Common stock issued upon exercise of warrants	`CommonStockIssuedUponExerciseOfWarrantsAmount`	$662.00K	USD	Annual
Common stock issued upon exercise of warrants	`CommonStockIssuedUponExerciseOfWarrantsAmount`	$1.24M	USD	Annual
Common stock issued upon exercise of warrants	`CommonStockIssuedUponExerciseOfWarrantsAmount`	$15.75M	USD	Annual
Common stock issued upon exercise of stock options	`StockIssuedDuringPeriodValueStockOptionsExercised`	$9.96M	USD	Annual
Common stock issued upon exercise of stock options	`StockIssuedDuringPeriodValueStockOptionsExercised`	$626.00K	USD	Annual
Common stock issued upon exercise of stock options	`StockIssuedDuringPeriodValueStockOptionsExercised`	$5.62M	USD	Annual
Common stock sold in public offering, net of offering costs	`StockIssuedDuringPeriodValueNewIssues`	$398.82M	USD	Annual
Common stock sold in public offering, net of offering costs	`StockIssuedDuringPeriodValueNewIssues`	$53.66M	USD	Annual
Common stock sold in public offering, net of offering costs (in shares)	`StockIssuedDuringPeriodSharesNewIssues`	25.30M	shares	Point-in-time
Common stock sold in private placement, net of offering costs	`StockIssuedDuringPeriodValueOther`	$44.01M	USD	Annual
Preferred stock sold in private placement, net of offering costs	`Preferredstocksoldinprivateplacementvalue`	$51.68M	USD	Annual
Vesting of restricted shares issued for services	`StockIssuedDuringPeriodValueRestrictedStockAwardNetOfForfeitures`	-	USD	Annual
Vesting of restricted shares issued for services	`StockIssuedDuringPeriodValueRestrictedStockAwardNetOfForfeitures`	-	USD	Annual
Vesting of restricted shares issued for services	`StockIssuedDuringPeriodValueRestrictedStockAwardNetOfForfeitures`	-	USD	Annual
Conversion of convertible preferred stock into common stock	`StockIssuedDuringPeriodValueConversionOfConvertibleSecurities`	-	USD	Annual
Conversion of convertible preferred stock into common stock	`StockIssuedDuringPeriodValueConversionOfConvertibleSecurities`	-	USD	Annual
Conversion of convertible preferred stock into common stock	`StockIssuedDuringPeriodValueConversionOfConvertibleSecurities`	-	USD	Annual
Cancellation of resticted shares	`StockCancelledDuringPeriodRestrictedSharesValue`	-	USD	Annual
Cancellation of resticted shares	`StockCancelledDuringPeriodRestrictedSharesValue`	-	USD	Annual
Beneficial conversion feature of preferred stock	`AdjustmentsToAdditionalPaidInCapitalPreferredStockWithConversionFeature`	$-49.45M	USD	Annual
Deemed dividend on beneficial conversion feature of preferred stock	`AdjustmentsToAdditionalPaidInCapitalOther`	$49.45M	USD	Annual
Unrealized loss on short- term investments	`OtherComprehensiveIncomeUnrealizedHoldingGainLossOnSecuritiesArisingDuringPeriodNetOfTax`	$-29.00K	USD	Annual
Unrealized loss on short- term investments	`OtherComprehensiveIncomeUnrealizedHoldingGainLossOnSecuritiesArisingDuringPeriodNetOfTax`	$-42.00K	USD	Annual
Unrealized loss on short- term investments	`OtherComprehensiveIncomeUnrealizedHoldingGainLossOnSecuritiesArisingDuringPeriodNetOfTax`	$-19.00K	USD	Annual
Net loss	`NetIncomeLoss`	$-32.58M	USD	1 Quarter
Net loss	`NetIncomeLoss`	$-25.85M	USD	1 Quarter
Net loss	`NetIncomeLoss`	$-22.15M	USD	1 Quarter
Net loss	`NetIncomeLoss`	$-30.66M	USD	1 Quarter
Net loss	`NetIncomeLoss`	$-52.89M	USD	Annual
Net loss	`NetIncomeLoss`	$-20.68M	USD	1 Quarter
Net loss	`NetIncomeLoss`	$-26.52M	USD	1 Quarter
Net loss	`NetIncomeLoss`	$-123.58M	USD	Annual
Net loss	`NetIncomeLoss`	$-23.38M	USD	1 Quarter
Net loss	`NetIncomeLoss`	$-33.83M	USD	1 Quarter
Net loss	`NetIncomeLoss`	$-92.06M	USD	Annual
Ending Balance	`StockholdersEquity`	$145.48M	USD	Point-in-time
Ending Balance	`StockholdersEquity`	$466.19M	USD	Point-in-time
Ending Balance	`StockholdersEquity`	$104.02M	USD	Point-in-time
Ending Balance	`StockholdersEquity`	$166.92M	USD	Point-in-time

Comprehensive Income 17 line items

Line Item	Tag	Value	Unit	Period
Net Loss	`NetIncomeLoss`	$-32.58M	USD	1 Quarter
Net Loss	`NetIncomeLoss`	$-25.85M	USD	1 Quarter
Net Loss	`NetIncomeLoss`	$-22.15M	USD	1 Quarter
Net Loss	`NetIncomeLoss`	$-30.66M	USD	1 Quarter
Net Loss	`NetIncomeLoss`	$-52.89M	USD	Annual
Net Loss	`NetIncomeLoss`	$-20.68M	USD	1 Quarter
Net Loss	`NetIncomeLoss`	$-26.52M	USD	1 Quarter
Net Loss	`NetIncomeLoss`	$-123.58M	USD	Annual
Net Loss	`NetIncomeLoss`	$-23.38M	USD	1 Quarter
Net Loss	`NetIncomeLoss`	$-33.83M	USD	1 Quarter
Net Loss	`NetIncomeLoss`	$-92.06M	USD	Annual
Net unrealized loss on short-term investments	`OtherComprehensiveIncomeUnrealizedHoldingGainLossOnSecuritiesArisingDuringPeriodNetOfTax`	$-29.00K	USD	Annual
Net unrealized loss on short-term investments	`OtherComprehensiveIncomeUnrealizedHoldingGainLossOnSecuritiesArisingDuringPeriodNetOfTax`	$-42.00K	USD	Annual
Net unrealized loss on short-term investments	`OtherComprehensiveIncomeUnrealizedHoldingGainLossOnSecuritiesArisingDuringPeriodNetOfTax`	$-19.00K	USD	Annual
Comprehensive Loss	`ComprehensiveIncomeNetOfTax`	$-92.09M	USD	Annual
Comprehensive Loss	`ComprehensiveIncomeNetOfTax`	$-123.62M	USD	Annual
Comprehensive Loss	`ComprehensiveIncomeNetOfTax`	$-52.91M	USD	Annual

Data is extracted from SEC EDGAR XBRL filings. Values shown are as reported in the filing.