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10-K Filing

Monte Rosa Therapeutics, Inc. CIK: 1826457 FY 2022
Filing Information
Form Type 10-K
Accession Number 0000950170-23-008440
Period End Date 20221231
Filing Date 20230316
Fiscal Year 2022
Fiscal Period FY
XBRL Instance glue-20221231_htm.xml
Filing Contents
Balance Sheet 69 line items
Line Item Tag Value Unit Period
Cash and cash equivalents CashAndCashEquivalentsAtCarryingValue $346.07M USD Point-in-time
Cash and cash equivalents CashAndCashEquivalentsAtCarryingValue $54.91M USD Point-in-time
Marketable securities MarketableSecurities - USD Point-in-time
Marketable securities MarketableSecurities $207.91M USD Point-in-time
Other receivables OtherReceivables - USD Point-in-time
Other receivables OtherReceivables $7.66M USD Point-in-time
Prepaid expenses and other current assets PrepaidExpenseAndOtherAssetsCurrent $4.44M USD Point-in-time
Prepaid expenses and other current assets PrepaidExpenseAndOtherAssetsCurrent $2.60M USD Point-in-time
Current restricted cash RestrictedCashCurrent - USD Point-in-time
Current restricted cash RestrictedCashCurrent $960.00K USD Point-in-time
Preferred stock, par value PreferredStockParOrStatedValuePerShare $0.00 USD Point-in-time
Preferred stock, par value PreferredStockParOrStatedValuePerShare $0.00 USD Point-in-time
Preferred stock, shares authorized PreferredStockSharesAuthorized 10.00M shares Point-in-time
Preferred stock, shares authorized PreferredStockSharesAuthorized 10.00M shares Point-in-time
Total current assets AssetsCurrent $348.67M USD Point-in-time
Total current assets AssetsCurrent $275.89M USD Point-in-time
Preferred stock, shares Issued PreferredStockSharesIssued 0.00 shares Point-in-time
Property and equipment, net PropertyPlantAndEquipmentNet $12.32M USD Point-in-time
Property and equipment, net PropertyPlantAndEquipmentNet $27.07M USD Point-in-time
Preferred stock, shares Issued PreferredStockSharesIssued 0.00 shares Point-in-time
Preferred stock, shares outstanding PreferredStockSharesOutstanding 0.00 shares Point-in-time
Operating lease right-of-use assets OperatingLeaseRightOfUseAsset $34.83M USD Point-in-time
Operating lease right-of-use assets OperatingLeaseRightOfUseAsset - USD Point-in-time
Preferred stock, shares outstanding PreferredStockSharesOutstanding 0.00 shares Point-in-time
Restricted cash, net of current RestrictedCashNoncurrent $4.32M USD Point-in-time
Restricted cash, net of current RestrictedCashNoncurrent $5.34M USD Point-in-time
Common stock, par or stated value per share CommonStockParOrStatedValuePerShare $0.00 USD Point-in-time
Common stock, par or stated value per share CommonStockParOrStatedValuePerShare $0.00 USD Point-in-time
Common stock, shares authorized CommonStockSharesAuthorized 500.00M shares Point-in-time
Other long-term assets OtherAssetsNoncurrent - USD Point-in-time
Other long-term assets OtherAssetsNoncurrent $278.00K USD Point-in-time
Common stock, shares authorized CommonStockSharesAuthorized 500.00M shares Point-in-time
Total assets Assets $366.33M USD Point-in-time
Total assets Assets $342.39M USD Point-in-time
Common stock, shares, issued CommonStockSharesIssued 49.45M shares Point-in-time
Common stock, shares, issued CommonStockSharesIssued 46.79M shares Point-in-time
Common stock shares outstanding CommonStockSharesOutstanding 49.32M shares Point-in-time
Common stock shares outstanding CommonStockSharesOutstanding 46.54M shares Point-in-time
Accounts payable AccountsPayableCurrent $7.86M USD Point-in-time
Accounts payable AccountsPayableCurrent $6.56M USD Point-in-time
Accrued expenses and other current liabilities AccountsPayableAndOtherAccruedLiabilitiesCurrent $14.58M USD Point-in-time
Accrued expenses and other current liabilities AccountsPayableAndOtherAccruedLiabilitiesCurrent $10.08M USD Point-in-time
Current portion of operating lease liability OperatingLeaseLiabilityCurrent $3.13M USD Point-in-time
Current portion of operating lease liability OperatingLeaseLiabilityCurrent - USD Point-in-time
Total current liabilities LiabilitiesCurrent $25.57M USD Point-in-time
Total current liabilities LiabilitiesCurrent $16.64M USD Point-in-time
Defined benefit plan liability DefinedBenefitPensionPlanLiabilitiesNoncurrent $2.18M USD Point-in-time
Defined benefit plan liability DefinedBenefitPensionPlanLiabilitiesNoncurrent $1.53M USD Point-in-time
Operating lease liability OperatingLeaseLiabilityNoncurrent $43.87M USD Point-in-time
Operating lease liability OperatingLeaseLiabilityNoncurrent - USD Point-in-time
Total liabilities Liabilities $70.98M USD Point-in-time
Total liabilities Liabilities $18.81M USD Point-in-time
Commitments and contingencies CommitmentsAndContingencies - USD Point-in-time
Commitments and contingencies CommitmentsAndContingencies - USD Point-in-time
Preferred stock, $0.0001 par value, 10,000,000 shares authorized, no shares issued and outstanding PreferredStockValue - USD Point-in-time
Preferred stock, $0.0001 par value, 10,000,000 shares authorized, no shares issued and outstanding PreferredStockValue - USD Point-in-time
Common stock, $0.0001 par value; 500,000,000 shares authorized, 49,445,802 shares issued and 49,323,531 shares outstanding as of December 31, 2022; and 500,000,000 shares authorized, 46,794,295 shares issued and 46,535,966 shares outstanding as of December 31, 2021 CommonStockValue $5.00K USD Point-in-time
Common stock, $0.0001 par value; 500,000,000 shares authorized, 49,445,802 shares issued and 49,323,531 shares outstanding as of December 31, 2022; and 500,000,000 shares authorized, 46,794,295 shares issued and 46,535,966 shares outstanding as of December 31, 2021 CommonStockValue $5.00K USD Point-in-time
Additional paid-in capital AdditionalPaidInCapitalCommonStock $471.57M USD Point-in-time
Additional paid-in capital AdditionalPaidInCapitalCommonStock $503.70M USD Point-in-time
Accumulated other comprehensive loss AccumulatedOtherComprehensiveIncomeLossNetOfTax $-1.75M USD Point-in-time
Accumulated other comprehensive loss AccumulatedOtherComprehensiveIncomeLossNetOfTax $-2.02M USD Point-in-time
Accumulated deficit RetainedEarningsAccumulatedDeficit $-230.54M USD Point-in-time
Accumulated deficit RetainedEarningsAccumulatedDeficit $-122.03M USD Point-in-time
Total stockholders' equity StockholdersEquity $271.41M USD Point-in-time
Total stockholders' equity StockholdersEquity $-48.73M USD Point-in-time
Total stockholders' equity StockholdersEquity $347.51M USD Point-in-time
Total liabilities and stockholders' equity LiabilitiesAndStockholdersEquity $366.33M USD Point-in-time
Total liabilities and stockholders' equity LiabilitiesAndStockholdersEquity $342.39M USD Point-in-time
Income Statement 36 line items
Line Item Tag Value Unit Period
Research and development ResearchAndDevelopmentExpense $85.06M USD Annual
Research and development ResearchAndDevelopmentExpense $57.16M USD Annual
General and administrative GeneralAndAdministrativeExpense $27.32M USD Annual
General and administrative GeneralAndAdministrativeExpense $15.73M USD Annual
Total operating expenses OperatingExpenses $72.88M USD Annual
Total operating expenses OperatingExpenses $112.38M USD Annual
Operating Income (Loss), Total OperatingIncomeLoss $-112.38M USD Annual
Operating Income (Loss), Total OperatingIncomeLoss $-72.88M USD Annual
Interest income, net InterestIncomeExpenseNonoperatingNet $46.00K USD Annual
Interest income, net InterestIncomeExpenseNonoperatingNet $3.76M USD Annual
Foreign currency exchange gain (loss), net ForeignCurrencyTransactionGainLossBeforeTax $-162.00K USD Annual
Foreign currency exchange gain (loss), net ForeignCurrencyTransactionGainLossBeforeTax $10.00K USD Annual
Gain on disposal of fixed assets GainLossOnDispositionOfAssets1 - USD Annual
Gain on disposal of fixed assets GainLossOnDispositionOfAssets1 $109.00K USD Annual
Changes in fair value of preferred stock tranche obligations, net ChangesInFairValueOfPreferredStockTrancheObligationsNet - USD Annual
Changes in fair value of preferred stock tranche obligations, net ChangesInFairValueOfPreferredStockTrancheObligationsNet $-960.00K USD Annual
Total other income (expense) NonoperatingIncomeExpense $3.88M USD Annual
Total other income (expense) NonoperatingIncomeExpense $-1.08M USD Annual
Net loss NetIncomeLoss $-108.50M USD Annual
Net loss NetIncomeLoss $-73.96M USD Annual
Net loss per share attributable to common stockholders - basic IncomeLossFromContinuingOperationsPerBasicShare $-2.96 USD Annual
Net loss per share attributable to common stockholders - basic IncomeLossFromContinuingOperationsPerBasicShare $-2.30 USD Annual
Net loss per share attributable to common stockholders - diluted IncomeLossFromContinuingOperationsPerDilutedShare $-2.96 USD Annual
Net loss per share attributable to common stockholders - diluted IncomeLossFromContinuingOperationsPerDilutedShare $-2.30 USD Annual
Weighted-average number of shares outstanding used in computing net loss per common share - basic WeightedAverageNumberOfSharesOutstandingBasic 25.00M shares Annual
Weighted-average number of shares outstanding used in computing net loss per common share - basic WeightedAverageNumberOfSharesOutstandingBasic 47.23M shares Annual
Weighted-average number of shares outstanding used in computing net loss per common share - diluted WeightedAverageNumberOfDilutedSharesOutstanding 47.23M shares Annual
Weighted-average number of shares outstanding used in computing net loss per common share - diluted WeightedAverageNumberOfDilutedSharesOutstanding 25.00M shares Annual
Net loss NetIncomeLoss $-108.50M USD Annual
Net loss NetIncomeLoss $-73.96M USD Annual
Provision for pension benefit obligation ProvisionForPensionBenefitObligation $-965.00K USD Annual
Provision for pension benefit obligation ProvisionForPensionBenefitObligation $718.00K USD Annual
Unrealized loss on available-for-sale securities DebtSecuritiesAvailableForSaleRealizedLoss $-449.00K USD Annual
Unrealized loss on available-for-sale securities DebtSecuritiesAvailableForSaleRealizedLoss - USD Annual
Comprehensive loss ComprehensiveIncomeNetOfTax $-74.92M USD Annual
Comprehensive loss ComprehensiveIncomeNetOfTax $-108.23M USD Annual
Cash Flow Statement 83 line items
Line Item Tag Value Unit Period
Proceeds from initial public offering, net of underwriting discount ProceedFromInitialPublicOfferingNetOfUnderwritingDiscount $17.89M USD Annual
Proceeds from initial public offering, net of underwriting discount ProceedFromInitialPublicOfferingNetOfUnderwritingDiscount $17.89M USD Annual
Issuance of common stock, net of underwriting discount NetOfUnderwritingDiscountOnIssuanceOfCommonStock $620.00K USD Annual
Net loss ProfitLoss $-108.50M USD Annual
Net loss ProfitLoss $-73.96M USD Annual
Issuance of common stock, net of underwriting discount NetOfUnderwritingDiscountOnIssuanceOfCommonStock $620.00K USD Annual
Stock-based compensation expense ShareBasedCompensation $5.20M USD Annual
Stock-based compensation expense ShareBasedCompensation $11.66M USD Annual
Depreciation Depreciation $2.13M USD Annual
Depreciation Depreciation $3.75M USD Annual
Noncash Lease Expense NoncashLeaseExpense - USD Annual
Noncash Lease Expense NoncashLeaseExpense $4.81M USD Annual
Net accretion of discounts/premiums on marketable securities AccretionOfDiscountsPremiumsOnMarketableSecuritiesNet $-1.95M USD Annual
Net accretion of discounts/premiums on marketable securities AccretionOfDiscountsPremiumsOnMarketableSecuritiesNet - USD Annual
Changes in fair value of preferred stock tranche obligations ChangesInFairValueOfPreferredStockTrancheObligationsNet - USD Annual
Changes in fair value of preferred stock tranche obligations ChangesInFairValueOfPreferredStockTrancheObligationsNet $-960.00K USD Annual
(Gain) Loss on disposal of property and equipment GainLossOnSaleOfPropertyPlantEquipment $-17.00K USD Annual
(Gain) Loss on disposal of property and equipment GainLossOnSaleOfPropertyPlantEquipment $109.00K USD Annual
Other receivables IncreaseDecreaseInOtherReceivables - USD Annual
Other receivables IncreaseDecreaseInOtherReceivables $187.00K USD Annual
Prepaid expenses and other current assets IncreaseDecreaseInPrepaidDeferredExpenseAndOtherAssets $2.13M USD Annual
Prepaid expenses and other current assets IncreaseDecreaseInPrepaidDeferredExpenseAndOtherAssets $704.00K USD Annual
Accounts payable IncreaseDecreaseInAccountsPayable $-706.00K USD Annual
Accounts payable IncreaseDecreaseInAccountsPayable $-744.00K USD Annual
Accrued expenses and other current liabilities IncreaseDecreaseInAccruedLiabilitiesAndOtherOperatingLiabilities $1.03M USD Annual
Accrued expenses and other current liabilities IncreaseDecreaseInAccruedLiabilitiesAndOtherOperatingLiabilities $6.59M USD Annual
Defined benefit plan liability DefinedBenefitPlanOtherChanges $-1.11M USD Annual
Defined benefit plan liability DefinedBenefitPlanOtherChanges $-74.00K USD Annual
Right-of-use assets and operating lease liabilities IncreaseDecreaseInOperatingLeaseLiability - USD Annual
Right-of-use assets and operating lease liabilities IncreaseDecreaseInOperatingLeaseLiability $-181.00K USD Annual
Net cash used in operating activities NetCashProvidedByUsedInOperatingActivities $-59.36M USD Annual
Net cash used in operating activities NetCashProvidedByUsedInOperatingActivities $-92.47M USD Annual
Purchases of property and equipment PaymentsToAcquirePropertyPlantAndEquipment $9.73M USD Annual
Purchases of property and equipment PaymentsToAcquirePropertyPlantAndEquipment $12.91M USD Annual
Proceeds from sale of property and equipment ProceedsFromSaleOfPropertyPlantAndEquipment $109.00K USD Annual
Proceeds from sale of property and equipment ProceedsFromSaleOfPropertyPlantAndEquipment $79.00K USD Annual
Purchases of marketable securities PaymentsToAcquireMarketableSecurities $384.42M USD Annual
Purchases of marketable securities PaymentsToAcquireMarketableSecurities - USD Annual
Proceeds from maturities of marketable securities ProceedsFromSaleAndMaturityOfMarketableSecurities $178.00M USD Annual
Proceeds from maturities of marketable securities ProceedsFromSaleAndMaturityOfMarketableSecurities - USD Annual
Net cash used in investing activities NetCashProvidedByUsedInInvestingActivities $-9.65M USD Annual
Net cash used in investing activities NetCashProvidedByUsedInInvestingActivities $-219.22M USD Annual
Proceeds from issuance of convertible preferred stock ProceedsFromIssuanceOfConvertiblePreferredStock $143.00M USD Annual
Proceeds from issuance of convertible preferred stock ProceedsFromIssuanceOfConvertiblePreferredStock - USD Annual
Payment of convertible preferred stock issuance costs PaymentsOfStockIssuanceCosts - USD Annual
Payment of convertible preferred stock issuance costs PaymentsOfStockIssuanceCosts $231.00K USD Annual
Proceeds from initial public offering, net of underwriting discount of $17,895 ProceedsFromIssuanceInitialPublicOffering $237.75M USD Annual
Proceeds from initial public offering, net of underwriting discount of $17,895 ProceedsFromIssuanceInitialPublicOffering - USD Annual
Issuance of common stock, net of issuance cost of $620 ProceedsFromIssuanceOfCommonStock $20.05M USD Annual
Issuance of common stock, net of issuance cost of $620 ProceedsFromIssuanceOfCommonStock - USD Annual
Payment of initial public offering issuance costs PaymentsForRepurchaseOfInitialPublicOffering - USD Annual
Payment of initial public offering issuance costs PaymentsForRepurchaseOfInitialPublicOffering $3.11M USD Annual
Payment of common stock issuance costs PaymentOfCommonStockIssuanceCost - USD Annual
Payment of common stock issuance costs PaymentOfCommonStockIssuanceCost $364.00K USD Annual
Proceeds from exercise of employee stock options ProceedsFromStockOptionsExercised $149.00K USD Annual
Proceeds from exercise of employee stock options ProceedsFromStockOptionsExercised $439.00K USD Annual
Proceeds from employee stock purchase plan ProceedsFromIssuanceOfCommonStockDividendReinvestmentPlan - USD Annual
Proceeds from employee stock purchase plan ProceedsFromIssuanceOfCommonStockDividendReinvestmentPlan $336.00K USD Annual
Net cash provided by financing activities NetCashProvidedByUsedInFinancingActivities $377.56M USD Annual
Net cash provided by financing activities NetCashProvidedByUsedInFinancingActivities $20.47M USD Annual
Net (decrease) increase in cash, cash equivalents and restricted cash CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseIncludingExchangeRateEffect $308.55M USD Annual
Net (decrease) increase in cash, cash equivalents and restricted cash CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseIncludingExchangeRateEffect $-291.22M USD Annual
Cash, cash equivalents and restricted cashbeginning of year CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents $351.41M USD Point-in-time
Cash, cash equivalents and restricted cashbeginning of year CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents $42.86M USD Point-in-time
Cash, cash equivalents and restricted cashbeginning of year CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents $60.19M USD Point-in-time
Cash, cash equivalents and restricted cashend of year CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents $351.41M USD Point-in-time
Cash, cash equivalents and restricted cashend of year CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents $42.86M USD Point-in-time
Cash, cash equivalents and restricted cashend of year CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents $60.19M USD Point-in-time
Cash and cash equivalents CashAndCashEquivalentsAtCarryingValue $346.07M USD Point-in-time
Cash and cash equivalents CashAndCashEquivalentsAtCarryingValue $54.91M USD Point-in-time
Restricted cash RestrictedCash $5.34M USD Point-in-time
Restricted cash RestrictedCash $5.28M USD Point-in-time
Total cash, cash equivalents and restricted cash CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents $351.41M USD Point-in-time
Total cash, cash equivalents and restricted cash CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents $42.86M USD Point-in-time
Total cash, cash equivalents and restricted cash CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents $60.19M USD Point-in-time
Conversion of convertible preferred stock into common stock ConversionOfConvertiblePreferredStockIntoCommonStock - USD Annual
Conversion of convertible preferred stock into common stock ConversionOfConvertiblePreferredStockIntoCommonStock $231.17M USD Annual
Settlement of preferred stock tranche obligation SettlementOfPreferredStockTrancheObligation $20.64M USD Annual
Settlement of preferred stock tranche obligation SettlementOfPreferredStockTrancheObligation - USD Annual
Reduction of right-of-use assets for lease incentives receivable ReductionOfRightOfUseAssetsForLeaseIncentivesReceivable $7.47M USD Annual
Reduction of right-of-use assets for lease incentives receivable ReductionOfRightOfUseAssetsForLeaseIncentivesReceivable - USD Annual
Purchases of property and equipment in accounts payable and accrued expenses CapitalExpendituresIncurredButNotYetPaid $656.00K USD Annual
Purchases of property and equipment in accounts payable and accrued expenses CapitalExpendituresIncurredButNotYetPaid $6.24M USD Annual
Stockholders Equity 23 line items
Line Item Tag Value Unit Period
Stock issuance costs PaymentsOfStockIssuanceCosts - USD Annual
Stock issuance costs PaymentsOfStockIssuanceCosts $231.00K USD Annual
Balance, amount StockholdersEquity $271.41M USD Point-in-time
Balance, amount StockholdersEquity $-48.73M USD Point-in-time
Balance, amount StockholdersEquity $347.51M USD Point-in-time
Conversion of convertible preferred stock into common stock StockIssuedDuringPeriodValueConversionOfUnits $231.17M USD Annual
Issuance of common stock in connection with initial public offering, net of issuance costs, amount StockIssuedDuringPeriodValueNewIssues $234.65M USD Annual
Exercise of common stock options StockIssuedDuringPeriodValueStockOptionsExercised $148.00K USD Annual
Exercise of common stock options StockIssuedDuringPeriodValueStockOptionsExercised $439.00K USD Annual
Exercise of common stock options, shares StockIssuedDuringPeriodSharesStockOptionsExercised 117,552.00 shares Annual
Stock-based compensation expense AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue $11.66M USD Annual
Stock-based compensation expense AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue $5.20M USD Annual
Provision for pension benefit obligation OtherComprehensiveIncomeLossPensionAndOtherPostretirementBenefitPlansAdjustmentNetOfTax $-965.00K USD Annual
Provision for pension benefit obligation OtherComprehensiveIncomeLossPensionAndOtherPostretirementBenefitPlansAdjustmentNetOfTax $718.00K USD Annual
Issuance of common stock, net of issuance costs, amount IssuanceOfCommonStockNetOfIssuanceCosts $19.69M USD Annual
Unrealized loss on available-for-sale securities DebtSecuritiesAvailableForSaleRealizedLoss $-449.00K USD Annual
Unrealized loss on available-for-sale securities DebtSecuritiesAvailableForSaleRealizedLoss - USD Annual
Issuance of shares under employee stock purchase plan StockIssuedDuringPeriodValueEmployeeStockPurchasePlan $336.00K USD Annual
Net loss NetIncomeLoss $-108.50M USD Annual
Net loss NetIncomeLoss $-73.96M USD Annual
Balance, amount StockholdersEquity $271.41M USD Point-in-time
Balance, amount StockholdersEquity $-48.73M USD Point-in-time
Balance, amount StockholdersEquity $347.51M USD Point-in-time

Data is extracted from SEC EDGAR XBRL filings. Values shown are as reported in the filing.

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