10-K Filing

ARROWHEAD PHARMACEUTICALS, INC. CIK: 879407 FY 2025

Filing Information

Form Type	10-K
Accession Number	`0000879407-25-000029`
Period End Date	20250930
Filing Date	20251125
Fiscal Year	2025
Fiscal Period	FY
XBRL Instance	arwr-20250930_htm.xml

Filing Contents

This filing contains the following financial statements:

Balance Sheet 162 Income Statement 132 Cash Flow Statement 228 Stockholders Equity 78

Balance Sheet 162 line items

Line Item	Tag	Value	Unit	Period
Common stock, par value (in dollars per share)	`CommonStockParOrStatedValuePerShare`	$0.00	USD	Point-in-time
Common stock, par value (in dollars per share)	`CommonStockParOrStatedValuePerShare`	$0.00	USD	Point-in-time
Common stock, par value (in dollars per share)	`CommonStockParOrStatedValuePerShare`	$0.00	USD	Point-in-time
Common stock, par value (in dollars per share)	`CommonStockParOrStatedValuePerShare`	$0.00	USD	Point-in-time
Common stock, shares authorized (in shares)	`CommonStockSharesAuthorized`	290.00M	shares	Point-in-time
Common stock, shares authorized (in shares)	`CommonStockSharesAuthorized`	290.00M	shares	Point-in-time
Common stock, shares authorized (in shares)	`CommonStockSharesAuthorized`	290.00M	shares	Point-in-time
Common stock, shares authorized (in shares)	`CommonStockSharesAuthorized`	290.00M	shares	Point-in-time
Common stock, shares issued (in shares)	`CommonStockSharesIssued`	124.38M	shares	Point-in-time
Common stock, shares issued (in shares)	`CommonStockSharesIssued`	124.38M	shares	Point-in-time
Common stock, shares issued (in shares)	`CommonStockSharesIssued`	135.70M	shares	Point-in-time
Common stock, shares issued (in shares)	`CommonStockSharesIssued`	135.70M	shares	Point-in-time
Common stock, shares outstanding (in shares)	`CommonStockSharesOutstanding`	124.38M	shares	Point-in-time
Common stock, shares outstanding (in shares)	`CommonStockSharesOutstanding`	124.38M	shares	Point-in-time
Common stock, shares outstanding (in shares)	`CommonStockSharesOutstanding`	135.70M	shares	Point-in-time
Common stock, shares outstanding (in shares)	`CommonStockSharesOutstanding`	135.70M	shares	Point-in-time
Treasury stock (in shares)	`TreasuryStockCommonShares`	0.00	shares	Point-in-time
Treasury stock (in shares)	`TreasuryStockCommonShares`	0.00	shares	Point-in-time
Treasury stock (in shares)	`TreasuryStockCommonShares`	2.66M	shares	Point-in-time
Treasury stock (in shares)	`TreasuryStockCommonShares`	2.66M	shares	Point-in-time
Cash, cash equivalents and restricted cash	`CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents`	$108.00M	USD	Point-in-time
Cash, cash equivalents and restricted cash	`CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents`	$108.00M	USD	Point-in-time
Cash, cash equivalents and restricted cash	`CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents`	$110.89M	USD	Point-in-time
Cash, cash equivalents and restricted cash	`CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents`	$110.89M	USD	Point-in-time
Cash, cash equivalents and restricted cash	`CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents`	$102.69M	USD	Point-in-time
Cash, cash equivalents and restricted cash	`CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents`	$102.69M	USD	Point-in-time
Cash, cash equivalents and restricted cash	`CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents`	$226.55M	USD	Point-in-time
Cash, cash equivalents and restricted cash	`CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents`	$226.55M	USD	Point-in-time
Accounts receivable	`AccountsReceivableNetCurrent`	-	USD	Point-in-time
Accounts receivable	`AccountsReceivableNetCurrent`	-	USD	Point-in-time
Accounts receivable	`AccountsReceivableNetCurrent`	$6.82M	USD	Point-in-time
Accounts receivable	`AccountsReceivableNetCurrent`	$6.82M	USD	Point-in-time
Available-for-sale securities, at fair value	`AvailableForSaleSecuritiesDebtSecuritiesCurrent`	$578.28M	USD	Point-in-time
Available-for-sale securities, at fair value	`AvailableForSaleSecuritiesDebtSecuritiesCurrent`	$578.28M	USD	Point-in-time
Available-for-sale securities, at fair value	`AvailableForSaleSecuritiesDebtSecuritiesCurrent`	$692.82M	USD	Point-in-time
Available-for-sale securities, at fair value	`AvailableForSaleSecuritiesDebtSecuritiesCurrent`	$692.82M	USD	Point-in-time
Prepaid expenses	`PrepaidExpenseCurrent`	$9.54M	USD	Point-in-time
Prepaid expenses	`PrepaidExpenseCurrent`	$9.54M	USD	Point-in-time
Prepaid expenses	`PrepaidExpenseCurrent`	$10.93M	USD	Point-in-time
Prepaid expenses	`PrepaidExpenseCurrent`	$10.93M	USD	Point-in-time
Other current assets	`OtherAssetsCurrent`	$4.97M	USD	Point-in-time
Other current assets	`OtherAssetsCurrent`	$4.97M	USD	Point-in-time
Other current assets	`OtherAssetsCurrent`	$13.52M	USD	Point-in-time
Other current assets	`OtherAssetsCurrent`	$13.52M	USD	Point-in-time
Total current assets	`AssetsCurrent`	$695.47M	USD	Point-in-time
Total current assets	`AssetsCurrent`	$695.47M	USD	Point-in-time
Total current assets	`AssetsCurrent`	$950.64M	USD	Point-in-time
Total current assets	`AssetsCurrent`	$950.64M	USD	Point-in-time
Property, plant and equipment, net	`PropertyPlantAndEquipmentNet`	$386.03M	USD	Point-in-time
Property, plant and equipment, net	`PropertyPlantAndEquipmentNet`	$386.03M	USD	Point-in-time
Property, plant and equipment, net	`PropertyPlantAndEquipmentNet`	$382.51M	USD	Point-in-time
Property, plant and equipment, net	`PropertyPlantAndEquipmentNet`	$382.51M	USD	Point-in-time
Intangible assets, net	`FiniteLivedIntangibleAssetsNet`	$8.56M	USD	Point-in-time
Intangible assets, net	`FiniteLivedIntangibleAssetsNet`	$8.56M	USD	Point-in-time
Intangible assets, net	`FiniteLivedIntangibleAssetsNet`	$6.86M	USD	Point-in-time
Intangible assets, net	`FiniteLivedIntangibleAssetsNet`	$6.86M	USD	Point-in-time
Right-of-use assets	`OperatingLeaseRightOfUseAsset`	$45.26M	USD	Point-in-time
Right-of-use assets	`OperatingLeaseRightOfUseAsset`	$45.26M	USD	Point-in-time
Right-of-use assets	`OperatingLeaseRightOfUseAsset`	$43.89M	USD	Point-in-time
Right-of-use assets	`OperatingLeaseRightOfUseAsset`	$43.89M	USD	Point-in-time
Other assets	`OtherAssetsNoncurrent`	$4.48M	USD	Point-in-time
Other assets	`OtherAssetsNoncurrent`	$4.48M	USD	Point-in-time
Other assets	`OtherAssetsNoncurrent`	$1.39M	USD	Point-in-time
Other assets	`OtherAssetsNoncurrent`	$1.39M	USD	Point-in-time
Total Assets	`Assets`	$1.14B	USD	Point-in-time
Total Assets	`Assets`	$1.14B	USD	Point-in-time
Total Assets	`Assets`	$1.39B	USD	Point-in-time
Total Assets	`Assets`	$1.39B	USD	Point-in-time
Accounts payable	`AccountsPayableCurrent`	$11.39M	USD	Point-in-time
Accounts payable	`AccountsPayableCurrent`	$11.39M	USD	Point-in-time
Accounts payable	`AccountsPayableCurrent`	$17.67M	USD	Point-in-time
Accounts payable	`AccountsPayableCurrent`	$17.67M	USD	Point-in-time
Accrued expenses	`AccruedLiabilitiesCurrent`	$63.02M	USD	Point-in-time
Accrued expenses	`AccruedLiabilitiesCurrent`	$63.02M	USD	Point-in-time
Accrued expenses	`AccruedLiabilitiesCurrent`	$90.42M	USD	Point-in-time
Accrued expenses	`AccruedLiabilitiesCurrent`	$90.42M	USD	Point-in-time
Accrued payroll and benefits	`EmployeeRelatedLiabilitiesCurrent`	$21.99M	USD	Point-in-time
Accrued payroll and benefits	`EmployeeRelatedLiabilitiesCurrent`	$21.99M	USD	Point-in-time
Accrued payroll and benefits	`EmployeeRelatedLiabilitiesCurrent`	$26.89M	USD	Point-in-time
Accrued payroll and benefits	`EmployeeRelatedLiabilitiesCurrent`	$26.89M	USD	Point-in-time
Lease liabilities	`OperatingLeaseLiabilityCurrent`	$6.34M	USD	Point-in-time
Lease liabilities	`OperatingLeaseLiabilityCurrent`	$6.34M	USD	Point-in-time
Lease liabilities	`OperatingLeaseLiabilityCurrent`	$7.29M	USD	Point-in-time
Lease liabilities	`OperatingLeaseLiabilityCurrent`	$7.29M	USD	Point-in-time
Deferred revenue	`ContractWithCustomerLiabilityCurrent`	-	USD	Point-in-time
Deferred revenue	`ContractWithCustomerLiabilityCurrent`	-	USD	Point-in-time
Deferred revenue	`ContractWithCustomerLiabilityCurrent`	$2.40M	USD	Point-in-time
Deferred revenue	`ContractWithCustomerLiabilityCurrent`	$2.40M	USD	Point-in-time
Credit facility	`LinesOfCreditCurrent`	-	USD	Point-in-time
Credit facility	`LinesOfCreditCurrent`	-	USD	Point-in-time
Credit facility	`LinesOfCreditCurrent`	$40.00M	USD	Point-in-time
Credit facility	`LinesOfCreditCurrent`	$40.00M	USD	Point-in-time
Other liabilities	`OtherLiabilitiesCurrent`	$432.00K	USD	Point-in-time
Other liabilities	`OtherLiabilitiesCurrent`	$432.00K	USD	Point-in-time
Other liabilities	`OtherLiabilitiesCurrent`	$10.81M	USD	Point-in-time
Other liabilities	`OtherLiabilitiesCurrent`	$10.81M	USD	Point-in-time
Total current liabilities	`LiabilitiesCurrent`	$103.17M	USD	Point-in-time
Total current liabilities	`LiabilitiesCurrent`	$103.17M	USD	Point-in-time
Total current liabilities	`LiabilitiesCurrent`	$195.49M	USD	Point-in-time
Total current liabilities	`LiabilitiesCurrent`	$195.49M	USD	Point-in-time
Lease liabilities, net of current portion	`OperatingLeaseLiabilityNoncurrent`	$111.03M	USD	Point-in-time
Lease liabilities, net of current portion	`OperatingLeaseLiabilityNoncurrent`	$111.03M	USD	Point-in-time
Lease liabilities, net of current portion	`OperatingLeaseLiabilityNoncurrent`	$104.11M	USD	Point-in-time
Lease liabilities, net of current portion	`OperatingLeaseLiabilityNoncurrent`	$104.11M	USD	Point-in-time
Liability related to the sale of future royalties	`RoyaltiesLiabilityNoncurrent`	$268.33M	USD	Point-in-time
Liability related to the sale of future royalties	`RoyaltiesLiabilityNoncurrent`	$268.33M	USD	Point-in-time
Liability related to the sale of future royalties	`RoyaltiesLiabilityNoncurrent`	$341.36M	USD	Point-in-time
Liability related to the sale of future royalties	`RoyaltiesLiabilityNoncurrent`	$341.36M	USD	Point-in-time
Liability related to the sale of future royalties	`RoyaltiesLiabilityNoncurrent`	$367.40M	USD	Point-in-time
Liability related to the sale of future royalties	`RoyaltiesLiabilityNoncurrent`	$367.40M	USD	Point-in-time
Credit facility, net of current portion	`LongTermLineOfCredit`	$393.18M	USD	Point-in-time
Credit facility, net of current portion	`LongTermLineOfCredit`	$393.18M	USD	Point-in-time
Credit facility, net of current portion	`LongTermLineOfCredit`	$214.88M	USD	Point-in-time
Credit facility, net of current portion	`LongTermLineOfCredit`	$214.88M	USD	Point-in-time
Total long-term liabilities	`LiabilitiesNoncurrent`	$845.57M	USD	Point-in-time
Total long-term liabilities	`LiabilitiesNoncurrent`	$845.57M	USD	Point-in-time
Total long-term liabilities	`LiabilitiesNoncurrent`	$686.39M	USD	Point-in-time
Total long-term liabilities	`LiabilitiesNoncurrent`	$686.39M	USD	Point-in-time
Commitments and contingencies (Note 7)	`CommitmentsAndContingencies`	-	USD	Point-in-time
Commitments and contingencies (Note 7)	`CommitmentsAndContingencies`	-	USD	Point-in-time
Commitments and contingencies (Note 7)	`CommitmentsAndContingencies`	-	USD	Point-in-time
Commitments and contingencies (Note 7)	`CommitmentsAndContingencies`	-	USD	Point-in-time
Common stock, $0.001 par value: Authorized 290,000 shares; issued and outstanding 135,702 and 124,376 shares at September 30, 2025 and 2024, respectively	`CommonStockValue`	$217.00K	USD	Point-in-time
Common stock, $0.001 par value: Authorized 290,000 shares; issued and outstanding 135,702 and 124,376 shares at September 30, 2025 and 2024, respectively	`CommonStockValue`	$217.00K	USD	Point-in-time
Common stock, $0.001 par value: Authorized 290,000 shares; issued and outstanding 135,702 and 124,376 shares at September 30, 2025 and 2024, respectively	`CommonStockValue`	$231.00K	USD	Point-in-time
Common stock, $0.001 par value: Authorized 290,000 shares; issued and outstanding 135,702 and 124,376 shares at September 30, 2025 and 2024, respectively	`CommonStockValue`	$231.00K	USD	Point-in-time
Additional paid-in capital	`AdditionalPaidInCapitalCommonStock`	$1.81B	USD	Point-in-time
Additional paid-in capital	`AdditionalPaidInCapitalCommonStock`	$1.81B	USD	Point-in-time
Additional paid-in capital	`AdditionalPaidInCapitalCommonStock`	$2.14B	USD	Point-in-time
Additional paid-in capital	`AdditionalPaidInCapitalCommonStock`	$2.14B	USD	Point-in-time
Accumulated other comprehensive income	`AccumulatedOtherComprehensiveIncomeLossNetOfTax`	$4.75M	USD	Point-in-time
Accumulated other comprehensive income	`AccumulatedOtherComprehensiveIncomeLossNetOfTax`	$4.75M	USD	Point-in-time
Accumulated other comprehensive income	`AccumulatedOtherComprehensiveIncomeLossNetOfTax`	$6.44M	USD	Point-in-time
Accumulated other comprehensive income	`AccumulatedOtherComprehensiveIncomeLossNetOfTax`	$6.44M	USD	Point-in-time
Accumulated deficit	`RetainedEarningsAccumulatedDeficit`	$-1.63B	USD	Point-in-time
Accumulated deficit	`RetainedEarningsAccumulatedDeficit`	$-1.63B	USD	Point-in-time
Accumulated deficit	`RetainedEarningsAccumulatedDeficit`	$-1.63B	USD	Point-in-time
Accumulated deficit	`RetainedEarningsAccumulatedDeficit`	$-1.63B	USD	Point-in-time
Treasury stock; at cost; 2,661 and 0 shares of common stock at September 30, 2025 and 2024, respectively	`TreasuryStockCommonValue`	-	USD	Point-in-time
Treasury stock; at cost; 2,661 and 0 shares of common stock at September 30, 2025 and 2024, respectively	`TreasuryStockCommonValue`	-	USD	Point-in-time
Treasury stock; at cost; 2,661 and 0 shares of common stock at September 30, 2025 and 2024, respectively	`TreasuryStockCommonValue`	$53.19M	USD	Point-in-time
Treasury stock; at cost; 2,661 and 0 shares of common stock at September 30, 2025 and 2024, respectively	`TreasuryStockCommonValue`	$53.19M	USD	Point-in-time
Total Arrowhead Pharmaceuticals, Inc. stockholders' equity	`StockholdersEquity`	$185.44M	USD	Point-in-time
Total Arrowhead Pharmaceuticals, Inc. stockholders' equity	`StockholdersEquity`	$185.44M	USD	Point-in-time
Total Arrowhead Pharmaceuticals, Inc. stockholders' equity	`StockholdersEquity`	$466.05M	USD	Point-in-time
Total Arrowhead Pharmaceuticals, Inc. stockholders' equity	`StockholdersEquity`	$466.05M	USD	Point-in-time
Noncontrolling interest	`MinorityInterest`	$5.62M	USD	Point-in-time
Noncontrolling interest	`MinorityInterest`	$5.62M	USD	Point-in-time
Noncontrolling interest	`MinorityInterest`	$37.36M	USD	Point-in-time
Noncontrolling interest	`MinorityInterest`	$37.36M	USD	Point-in-time
Total noncontrolling interest and stockholders' equity	`StockholdersEquityIncludingPortionAttributableToNoncontrollingInterest`	$418.34M	USD	Point-in-time
Total noncontrolling interest and stockholders' equity	`StockholdersEquityIncludingPortionAttributableToNoncontrollingInterest`	$418.34M	USD	Point-in-time
Total noncontrolling interest and stockholders' equity	`StockholdersEquityIncludingPortionAttributableToNoncontrollingInterest`	$287.16M	USD	Point-in-time
Total noncontrolling interest and stockholders' equity	`StockholdersEquityIncludingPortionAttributableToNoncontrollingInterest`	$287.16M	USD	Point-in-time
Total noncontrolling interest and stockholders' equity	`StockholdersEquityIncludingPortionAttributableToNoncontrollingInterest`	$191.06M	USD	Point-in-time
Total noncontrolling interest and stockholders' equity	`StockholdersEquityIncludingPortionAttributableToNoncontrollingInterest`	$191.06M	USD	Point-in-time
Total noncontrolling interest and stockholders' equity	`StockholdersEquityIncludingPortionAttributableToNoncontrollingInterest`	$503.42M	USD	Point-in-time
Total noncontrolling interest and stockholders' equity	`StockholdersEquityIncludingPortionAttributableToNoncontrollingInterest`	$503.42M	USD	Point-in-time
Total Liabilities, Noncontrolling Interest and Stockholders' Equity	`LiabilitiesAndStockholdersEquity`	$1.14B	USD	Point-in-time
Total Liabilities, Noncontrolling Interest and Stockholders' Equity	`LiabilitiesAndStockholdersEquity`	$1.14B	USD	Point-in-time
Total Liabilities, Noncontrolling Interest and Stockholders' Equity	`LiabilitiesAndStockholdersEquity`	$1.39B	USD	Point-in-time
Total Liabilities, Noncontrolling Interest and Stockholders' Equity	`LiabilitiesAndStockholdersEquity`	$1.39B	USD	Point-in-time

Income Statement 132 line items

Line Item	Tag	Value	Unit	Period
Revenue	`RevenueFromContractWithCustomerExcludingAssessedTax`	$240.74M	USD	Annual
Revenue	`RevenueFromContractWithCustomerExcludingAssessedTax`	$240.74M	USD	Annual
Revenue	`RevenueFromContractWithCustomerExcludingAssessedTax`	$3.55M	USD	Annual
Revenue	`RevenueFromContractWithCustomerExcludingAssessedTax`	$3.55M	USD	Annual
Revenue	`RevenueFromContractWithCustomerExcludingAssessedTax`	$829.45M	USD	Annual
Revenue	`RevenueFromContractWithCustomerExcludingAssessedTax`	$829.45M	USD	Annual
Research and development	`ResearchAndDevelopmentExpense`	$353.19M	USD	Annual
Research and development	`ResearchAndDevelopmentExpense`	$353.19M	USD	Annual
Research and development	`ResearchAndDevelopmentExpense`	$505.87M	USD	Annual
Research and development	`ResearchAndDevelopmentExpense`	$505.87M	USD	Annual
Research and development	`ResearchAndDevelopmentExpense`	$607.16M	USD	Annual
Research and development	`ResearchAndDevelopmentExpense`	$607.16M	USD	Annual
General and administrative	`GeneralAndAdministrativeExpense`	$92.55M	USD	Annual
General and administrative	`GeneralAndAdministrativeExpense`	$92.55M	USD	Annual
General and administrative	`GeneralAndAdministrativeExpense`	$98.76M	USD	Annual
General and administrative	`GeneralAndAdministrativeExpense`	$98.76M	USD	Annual
General and administrative	`GeneralAndAdministrativeExpense`	$123.94M	USD	Annual
General and administrative	`GeneralAndAdministrativeExpense`	$123.94M	USD	Annual
Total operating expenses	`OperatingExpenses`	$445.74M	USD	Annual
Total operating expenses	`OperatingExpenses`	$445.74M	USD	Annual
Total operating expenses	`OperatingExpenses`	$604.63M	USD	Annual
Total operating expenses	`OperatingExpenses`	$604.63M	USD	Annual
Total operating expenses	`OperatingExpenses`	$731.10M	USD	Annual
Total operating expenses	`OperatingExpenses`	$731.10M	USD	Annual
Operating income (loss)	`OperatingIncomeLoss`	$-205.00M	USD	Annual
Operating income (loss)	`OperatingIncomeLoss`	$-205.00M	USD	Annual
Operating income (loss)	`OperatingIncomeLoss`	$-601.08M	USD	Annual
Operating income (loss)	`OperatingIncomeLoss`	$-601.08M	USD	Annual
Operating income (loss)	`OperatingIncomeLoss`	$98.35M	USD	Annual
Operating income (loss)	`OperatingIncomeLoss`	$98.35M	USD	Annual
Interest income	`InvestmentIncomeInterestAndDividend`	$15.30M	USD	Annual
Interest income	`InvestmentIncomeInterestAndDividend`	$15.30M	USD	Annual
Interest income	`InvestmentIncomeInterestAndDividend`	$22.72M	USD	Annual
Interest income	`InvestmentIncomeInterestAndDividend`	$22.72M	USD	Annual
Interest income	`InvestmentIncomeInterestAndDividend`	$37.29M	USD	Annual
Interest income	`InvestmentIncomeInterestAndDividend`	$37.29M	USD	Annual
Interest expense	`InterestExpenseNonoperating`	$18.33M	USD	Annual
Interest expense	`InterestExpenseNonoperating`	$18.33M	USD	Annual
Interest expense	`InterestExpenseNonoperating`	$32.35M	USD	Annual
Interest expense	`InterestExpenseNonoperating`	$32.35M	USD	Annual
Interest expense	`InterestExpenseNonoperating`	$89.36M	USD	Annual
Interest expense	`InterestExpenseNonoperating`	$89.36M	USD	Annual
Other, net	`OtherNonoperatingIncomeExpense`	$1.54M	USD	Annual
Other, net	`OtherNonoperatingIncomeExpense`	$1.54M	USD	Annual
Other, net	`OtherNonoperatingIncomeExpense`	$-1.75M	USD	Annual
Other, net	`OtherNonoperatingIncomeExpense`	$-1.75M	USD	Annual
Other, net	`OtherNonoperatingIncomeExpense`	$5.26M	USD	Annual
Other, net	`OtherNonoperatingIncomeExpense`	$5.26M	USD	Annual
Total other expense	`NonoperatingIncomeExpense`	$-1.49M	USD	Annual
Total other expense	`NonoperatingIncomeExpense`	$-1.49M	USD	Annual
Total other expense	`NonoperatingIncomeExpense`	$-11.38M	USD	Annual
Total other expense	`NonoperatingIncomeExpense`	$-11.38M	USD	Annual
Total other expense	`NonoperatingIncomeExpense`	$-46.81M	USD	Annual
Total other expense	`NonoperatingIncomeExpense`	$-46.81M	USD	Annual
Income (loss) before income tax expense and noncontrolling interest	`IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest`	$-206.49M	USD	Annual
Income (loss) before income tax expense and noncontrolling interest	`IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest`	$-206.49M	USD	Annual
Income (loss) before income tax expense and noncontrolling interest	`IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest`	$-612.46M	USD	Annual
Income (loss) before income tax expense and noncontrolling interest	`IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest`	$-612.46M	USD	Annual
Income (loss) before income tax expense and noncontrolling interest	`IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest`	$51.53M	USD	Annual
Income (loss) before income tax expense and noncontrolling interest	`IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest`	$51.53M	USD	Annual
Income tax expense (benefit)	`IncomeTaxExpenseBenefit`	$2.78M	USD	Annual
Income tax expense (benefit)	`IncomeTaxExpenseBenefit`	$2.78M	USD	Annual
Income tax expense (benefit)	`IncomeTaxExpenseBenefit`	$-2.77M	USD	Annual
Income tax expense (benefit)	`IncomeTaxExpenseBenefit`	$-2.77M	USD	Annual
Income tax expense (benefit)	`IncomeTaxExpenseBenefit`	$21.42M	USD	Annual
Income tax expense (benefit)	`IncomeTaxExpenseBenefit`	$21.42M	USD	Annual
Net income (loss) including noncontrolling interest	`ProfitLoss`	$-209.28M	USD	Annual
Net income (loss) including noncontrolling interest	`ProfitLoss`	$-209.28M	USD	Annual
Net income (loss) including noncontrolling interest	`ProfitLoss`	$-609.69M	USD	Annual
Net income (loss) including noncontrolling interest	`ProfitLoss`	$-609.69M	USD	Annual
Net income (loss) including noncontrolling interest	`ProfitLoss`	$30.11M	USD	Annual
Net income (loss) including noncontrolling interest	`ProfitLoss`	$30.11M	USD	Annual
Net income (loss) attributable to noncontrolling interest, net of tax	`NetIncomeLossAttributableToNoncontrollingInterest`	$-4.00M	USD	Annual
Net income (loss) attributable to noncontrolling interest, net of tax	`NetIncomeLossAttributableToNoncontrollingInterest`	$-4.00M	USD	Annual
Net income (loss) attributable to noncontrolling interest, net of tax	`NetIncomeLossAttributableToNoncontrollingInterest`	$-10.20M	USD	Annual
Net income (loss) attributable to noncontrolling interest, net of tax	`NetIncomeLossAttributableToNoncontrollingInterest`	$-10.20M	USD	Annual
Net income (loss) attributable to noncontrolling interest, net of tax	`NetIncomeLossAttributableToNoncontrollingInterest`	$31.75M	USD	Annual
Net income (loss) attributable to noncontrolling interest, net of tax	`NetIncomeLossAttributableToNoncontrollingInterest`	$31.75M	USD	Annual
Net loss attributable to Arrowhead Pharmaceuticals, Inc.	`NetIncomeLoss`	$-205.28M	USD	Annual
Net loss attributable to Arrowhead Pharmaceuticals, Inc.	`NetIncomeLoss`	$-205.28M	USD	Annual
Net loss attributable to Arrowhead Pharmaceuticals, Inc.	`NetIncomeLoss`	$-599.49M	USD	Annual
Net loss attributable to Arrowhead Pharmaceuticals, Inc.	`NetIncomeLoss`	$-599.49M	USD	Annual
Net loss attributable to Arrowhead Pharmaceuticals, Inc.	`NetIncomeLoss`	$-1.63M	USD	Annual
Net loss attributable to Arrowhead Pharmaceuticals, Inc.	`NetIncomeLoss`	$-1.63M	USD	Annual
Basic (in dollars per share)	`EarningsPerShareBasic`	$-1.92	USD	Annual
Basic (in dollars per share)	`EarningsPerShareBasic`	$-1.92	USD	Annual
Basic (in dollars per share)	`EarningsPerShareBasic`	$-5.00	USD	Annual
Basic (in dollars per share)	`EarningsPerShareBasic`	$-5.00	USD	Annual
Basic (in dollars per share)	`EarningsPerShareBasic`	$-0.01	USD	Annual
Basic (in dollars per share)	`EarningsPerShareBasic`	$-0.01	USD	Annual
Diluted (in dollars per share)	`EarningsPerShareDiluted`	$-1.92	USD	Annual
Diluted (in dollars per share)	`EarningsPerShareDiluted`	$-1.92	USD	Annual
Diluted (in dollars per share)	`EarningsPerShareDiluted`	$-5.00	USD	Annual
Diluted (in dollars per share)	`EarningsPerShareDiluted`	$-5.00	USD	Annual
Diluted (in dollars per share)	`EarningsPerShareDiluted`	$-0.01	USD	Annual
Diluted (in dollars per share)	`EarningsPerShareDiluted`	$-0.01	USD	Annual
Basic (in shares)	`WeightedAverageNumberOfSharesOutstandingBasic`	106.75M	shares	Annual
Basic (in shares)	`WeightedAverageNumberOfSharesOutstandingBasic`	106.75M	shares	Annual
Basic (in shares)	`WeightedAverageNumberOfSharesOutstandingBasic`	119.78M	shares	Annual
Basic (in shares)	`WeightedAverageNumberOfSharesOutstandingBasic`	119.78M	shares	Annual
Basic (in shares)	`WeightedAverageNumberOfSharesOutstandingBasic`	133.76M	shares	Annual
Basic (in shares)	`WeightedAverageNumberOfSharesOutstandingBasic`	133.76M	shares	Annual
Diluted (in shares)	`WeightedAverageNumberOfDilutedSharesOutstanding`	106.75M	shares	Annual
Diluted (in shares)	`WeightedAverageNumberOfDilutedSharesOutstanding`	106.75M	shares	Annual
Diluted (in shares)	`WeightedAverageNumberOfDilutedSharesOutstanding`	119.78M	shares	Annual
Diluted (in shares)	`WeightedAverageNumberOfDilutedSharesOutstanding`	119.78M	shares	Annual
Diluted (in shares)	`WeightedAverageNumberOfDilutedSharesOutstanding`	133.76M	shares	Annual
Diluted (in shares)	`WeightedAverageNumberOfDilutedSharesOutstanding`	133.76M	shares	Annual
Unrealized gains (losses) on available-for-sale securities	`OtherComprehensiveIncomeLossAvailableForSaleSecuritiesAdjustmentNetOfTax`	$-2.96M	USD	Annual
Unrealized gains (losses) on available-for-sale securities	`OtherComprehensiveIncomeLossAvailableForSaleSecuritiesAdjustmentNetOfTax`	$-2.96M	USD	Annual
Unrealized gains (losses) on available-for-sale securities	`OtherComprehensiveIncomeLossAvailableForSaleSecuritiesAdjustmentNetOfTax`	$3.77M	USD	Annual
Unrealized gains (losses) on available-for-sale securities	`OtherComprehensiveIncomeLossAvailableForSaleSecuritiesAdjustmentNetOfTax`	$3.77M	USD	Annual
Unrealized gains (losses) on available-for-sale securities	`OtherComprehensiveIncomeLossAvailableForSaleSecuritiesAdjustmentNetOfTax`	$2.12M	USD	Annual
Unrealized gains (losses) on available-for-sale securities	`OtherComprehensiveIncomeLossAvailableForSaleSecuritiesAdjustmentNetOfTax`	$2.12M	USD	Annual
Foreign currency translation adjustments	`OtherComprehensiveIncomeLossForeignCurrencyTransactionAndTranslationAdjustmentNetOfTax`	$-122.00K	USD	Annual
Foreign currency translation adjustments	`OtherComprehensiveIncomeLossForeignCurrencyTransactionAndTranslationAdjustmentNetOfTax`	$-122.00K	USD	Annual
Foreign currency translation adjustments	`OtherComprehensiveIncomeLossForeignCurrencyTransactionAndTranslationAdjustmentNetOfTax`	$4.20M	USD	Annual
Foreign currency translation adjustments	`OtherComprehensiveIncomeLossForeignCurrencyTransactionAndTranslationAdjustmentNetOfTax`	$4.20M	USD	Annual
Foreign currency translation adjustments	`OtherComprehensiveIncomeLossForeignCurrencyTransactionAndTranslationAdjustmentNetOfTax`	$-432.00K	USD	Annual
Foreign currency translation adjustments	`OtherComprehensiveIncomeLossForeignCurrencyTransactionAndTranslationAdjustmentNetOfTax`	$-432.00K	USD	Annual
Comprehensive income (loss) attributed to noncontrolling interest	`ComprehensiveIncomeNetOfTaxAttributableToNoncontrollingInterest`	$-4.00M	USD	Annual
Comprehensive income (loss) attributed to noncontrolling interest	`ComprehensiveIncomeNetOfTaxAttributableToNoncontrollingInterest`	$-4.00M	USD	Annual
Comprehensive income (loss) attributed to noncontrolling interest	`ComprehensiveIncomeNetOfTaxAttributableToNoncontrollingInterest`	$-10.20M	USD	Annual
Comprehensive income (loss) attributed to noncontrolling interest	`ComprehensiveIncomeNetOfTaxAttributableToNoncontrollingInterest`	$-10.20M	USD	Annual
Comprehensive income (loss) attributed to noncontrolling interest	`ComprehensiveIncomeNetOfTaxAttributableToNoncontrollingInterest`	$31.75M	USD	Annual
Comprehensive income (loss) attributed to noncontrolling interest	`ComprehensiveIncomeNetOfTaxAttributableToNoncontrollingInterest`	$31.75M	USD	Annual
Other comprehensive income (loss)	`ComprehensiveIncomeNetOfTaxIncludingPortionAttributableToNoncontrollingInterest`	$-212.36M	USD	Annual
Other comprehensive income (loss)	`ComprehensiveIncomeNetOfTaxIncludingPortionAttributableToNoncontrollingInterest`	$-212.36M	USD	Annual
Other comprehensive income (loss)	`ComprehensiveIncomeNetOfTaxIncludingPortionAttributableToNoncontrollingInterest`	$-601.72M	USD	Annual
Other comprehensive income (loss)	`ComprehensiveIncomeNetOfTaxIncludingPortionAttributableToNoncontrollingInterest`	$-601.72M	USD	Annual
Other comprehensive income (loss)	`ComprehensiveIncomeNetOfTaxIncludingPortionAttributableToNoncontrollingInterest`	$31.81M	USD	Annual
Other comprehensive income (loss)	`ComprehensiveIncomeNetOfTaxIncludingPortionAttributableToNoncontrollingInterest`	$31.81M	USD	Annual

Cash Flow Statement 228 line items

Line Item	Tag	Value	Unit	Period
Net income (loss)	`ProfitLoss`	$-209.28M	USD	Annual
Net income (loss)	`ProfitLoss`	$-209.28M	USD	Annual
Net income (loss)	`ProfitLoss`	$-609.69M	USD	Annual
Net income (loss)	`ProfitLoss`	$-609.69M	USD	Annual
Net income (loss)	`ProfitLoss`	$30.11M	USD	Annual
Net income (loss)	`ProfitLoss`	$30.11M	USD	Annual
Stock-based compensation	`ShareBasedCompensation`	$78.13M	USD	Annual
Stock-based compensation	`ShareBasedCompensation`	$78.13M	USD	Annual
Stock-based compensation	`ShareBasedCompensation`	$73.97M	USD	Annual
Stock-based compensation	`ShareBasedCompensation`	$73.97M	USD	Annual
Stock-based compensation	`ShareBasedCompensation`	$63.37M	USD	Annual
Stock-based compensation	`ShareBasedCompensation`	$63.37M	USD	Annual
Depreciation and amortization	`DepreciationAndAmortization`	$12.49M	USD	Annual
Depreciation and amortization	`DepreciationAndAmortization`	$12.49M	USD	Annual
Depreciation and amortization	`DepreciationAndAmortization`	$18.59M	USD	Annual
Depreciation and amortization	`DepreciationAndAmortization`	$18.59M	USD	Annual
Depreciation and amortization	`DepreciationAndAmortization`	$23.93M	USD	Annual
Depreciation and amortization	`DepreciationAndAmortization`	$23.93M	USD	Annual
Accretion of note premiums/discounts	`InvestmentIncomeNetAmortizationOfDiscountAndPremium`	$2.02M	USD	Annual
Accretion of note premiums/discounts	`InvestmentIncomeNetAmortizationOfDiscountAndPremium`	$2.02M	USD	Annual
Accretion of note premiums/discounts	`InvestmentIncomeNetAmortizationOfDiscountAndPremium`	$3.24M	USD	Annual
Accretion of note premiums/discounts	`InvestmentIncomeNetAmortizationOfDiscountAndPremium`	$3.24M	USD	Annual
Accretion of note premiums/discounts	`InvestmentIncomeNetAmortizationOfDiscountAndPremium`	$5.79M	USD	Annual
Accretion of note premiums/discounts	`InvestmentIncomeNetAmortizationOfDiscountAndPremium`	$5.79M	USD	Annual
Non-cash interest expense on liability related to the sale of future royalties	`NoncashInterestExpenseLiabilityRelatedToSaleOfFutureRoyalties`	$18.33M	USD	Annual
Non-cash interest expense on liability related to the sale of future royalties	`NoncashInterestExpenseLiabilityRelatedToSaleOfFutureRoyalties`	$18.33M	USD	Annual
Non-cash interest expense on liability related to the sale of future royalties	`NoncashInterestExpenseLiabilityRelatedToSaleOfFutureRoyalties`	$23.04M	USD	Annual
Non-cash interest expense on liability related to the sale of future royalties	`NoncashInterestExpenseLiabilityRelatedToSaleOfFutureRoyalties`	$23.04M	USD	Annual
Non-cash interest expense on liability related to the sale of future royalties	`NoncashInterestExpenseLiabilityRelatedToSaleOfFutureRoyalties`	$26.04M	USD	Annual
Non-cash interest expense on liability related to the sale of future royalties	`NoncashInterestExpenseLiabilityRelatedToSaleOfFutureRoyalties`	$26.04M	USD	Annual
Non-cash interest expense on credit facility	`PaidInKindInterest`	-	USD	Annual
Non-cash interest expense on credit facility	`PaidInKindInterest`	-	USD	Annual
Non-cash interest expense on credit facility	`PaidInKindInterest`	$9.32M	USD	Annual
Non-cash interest expense on credit facility	`PaidInKindInterest`	$9.32M	USD	Annual
Non-cash interest expense on credit facility	`PaidInKindInterest`	$63.33M	USD	Annual
Non-cash interest expense on credit facility	`PaidInKindInterest`	$63.33M	USD	Annual
Non-cash gain on treasury stock received	`GainLossOnTreasuryStockSettlement`	-	USD	Annual
Non-cash gain on treasury stock received	`GainLossOnTreasuryStockSettlement`	-	USD	Annual
Non-cash gain on treasury stock received	`GainLossOnTreasuryStockSettlement`	-	USD	Annual
Non-cash gain on treasury stock received	`GainLossOnTreasuryStockSettlement`	-	USD	Annual
Non-cash gain on treasury stock received	`GainLossOnTreasuryStockSettlement`	$3.19M	USD	Annual
Non-cash gain on treasury stock received	`GainLossOnTreasuryStockSettlement`	$3.19M	USD	Annual
Realized loss on investments	`RealizedInvestmentGainsLosses`	-	USD	Annual
Realized loss on investments	`RealizedInvestmentGainsLosses`	-	USD	Annual
Realized loss on investments	`RealizedInvestmentGainsLosses`	$-80.00K	USD	Annual
Realized loss on investments	`RealizedInvestmentGainsLosses`	$-80.00K	USD	Annual
Realized loss on investments	`RealizedInvestmentGainsLosses`	-	USD	Annual
Realized loss on investments	`RealizedInvestmentGainsLosses`	-	USD	Annual
Accounts receivable	`IncreaseDecreaseInAccountsReceivable`	$-1.41M	USD	Annual
Accounts receivable	`IncreaseDecreaseInAccountsReceivable`	$-1.41M	USD	Annual
Accounts receivable	`IncreaseDecreaseInAccountsReceivable`	-	USD	Annual
Accounts receivable	`IncreaseDecreaseInAccountsReceivable`	-	USD	Annual
Accounts receivable	`IncreaseDecreaseInAccountsReceivable`	$56.97M	USD	Annual
Accounts receivable	`IncreaseDecreaseInAccountsReceivable`	$56.97M	USD	Annual
Prepaid expenses and other current assets	`IncreaseDecreaseInPrepaidDeferredExpenseAndOtherAssets`	$-11.60M	USD	Annual
Prepaid expenses and other current assets	`IncreaseDecreaseInPrepaidDeferredExpenseAndOtherAssets`	$-11.60M	USD	Annual
Prepaid expenses and other current assets	`IncreaseDecreaseInPrepaidDeferredExpenseAndOtherAssets`	$1.66M	USD	Annual
Prepaid expenses and other current assets	`IncreaseDecreaseInPrepaidDeferredExpenseAndOtherAssets`	$1.66M	USD	Annual
Prepaid expenses and other current assets	`IncreaseDecreaseInPrepaidDeferredExpenseAndOtherAssets`	$9.94M	USD	Annual
Prepaid expenses and other current assets	`IncreaseDecreaseInPrepaidDeferredExpenseAndOtherAssets`	$9.94M	USD	Annual
Accounts payable	`IncreaseDecreaseInAccountsPayable`	$33.00M	USD	Annual
Accounts payable	`IncreaseDecreaseInAccountsPayable`	$33.00M	USD	Annual
Accounts payable	`IncreaseDecreaseInAccountsPayable`	$-5.54M	USD	Annual
Accounts payable	`IncreaseDecreaseInAccountsPayable`	$-5.54M	USD	Annual
Accounts payable	`IncreaseDecreaseInAccountsPayable`	$6.29M	USD	Annual
Accounts payable	`IncreaseDecreaseInAccountsPayable`	$6.29M	USD	Annual
Accrued expenses	`IncreaseDecreaseInAccruedLiabilities`	$-14.96M	USD	Annual
Accrued expenses	`IncreaseDecreaseInAccruedLiabilities`	$-14.96M	USD	Annual
Accrued expenses	`IncreaseDecreaseInAccruedLiabilities`	$32.12M	USD	Annual
Accrued expenses	`IncreaseDecreaseInAccruedLiabilities`	$32.12M	USD	Annual
Accrued expenses	`IncreaseDecreaseInAccruedLiabilities`	$41.50M	USD	Annual
Accrued expenses	`IncreaseDecreaseInAccruedLiabilities`	$41.50M	USD	Annual
Deferred revenue	`IncreaseDecreaseInContractWithCustomerLiability`	$-129.18M	USD	Annual
Deferred revenue	`IncreaseDecreaseInContractWithCustomerLiability`	$-129.18M	USD	Annual
Deferred revenue	`IncreaseDecreaseInContractWithCustomerLiability`	$-866.00K	USD	Annual
Deferred revenue	`IncreaseDecreaseInContractWithCustomerLiability`	$-866.00K	USD	Annual
Deferred revenue	`IncreaseDecreaseInContractWithCustomerLiability`	$2.40M	USD	Annual
Deferred revenue	`IncreaseDecreaseInContractWithCustomerLiability`	$2.40M	USD	Annual
Operating lease, net	`IncreaseDecreaseInOperatingLeaseLiability`	$46.59M	USD	Annual
Operating lease, net	`IncreaseDecreaseInOperatingLeaseLiability`	$46.59M	USD	Annual
Operating lease, net	`IncreaseDecreaseInOperatingLeaseLiability`	$2.24M	USD	Annual
Operating lease, net	`IncreaseDecreaseInOperatingLeaseLiability`	$2.24M	USD	Annual
Operating lease, net	`IncreaseDecreaseInOperatingLeaseLiability`	$-4.61M	USD	Annual
Operating lease, net	`IncreaseDecreaseInOperatingLeaseLiability`	$-4.61M	USD	Annual
Other	`IncreaseDecreaseInOtherOperatingCapitalNet`	-	USD	Annual
Other	`IncreaseDecreaseInOtherOperatingCapitalNet`	-	USD	Annual
Other	`IncreaseDecreaseInOtherOperatingCapitalNet`	$1.20M	USD	Annual
Other	`IncreaseDecreaseInOtherOperatingCapitalNet`	$1.20M	USD	Annual
Other	`IncreaseDecreaseInOtherOperatingCapitalNet`	$-3.09M	USD	Annual
Other	`IncreaseDecreaseInOtherOperatingCapitalNet`	$-3.09M	USD	Annual
Net cash provided by (used in) operating activities	`NetCashProvidedByUsedInOperatingActivities`	$-153.89M	USD	Annual
Net cash provided by (used in) operating activities	`NetCashProvidedByUsedInOperatingActivities`	$-153.89M	USD	Annual
Net cash provided by (used in) operating activities	`NetCashProvidedByUsedInOperatingActivities`	$-462.85M	USD	Annual
Net cash provided by (used in) operating activities	`NetCashProvidedByUsedInOperatingActivities`	$-462.85M	USD	Annual
Net cash provided by (used in) operating activities	`NetCashProvidedByUsedInOperatingActivities`	$179.55M	USD	Annual
Net cash provided by (used in) operating activities	`NetCashProvidedByUsedInOperatingActivities`	$179.55M	USD	Annual
Purchases of property, plant and equipment	`PaymentsToAcquirePropertyPlantAndEquipment`	$176.74M	USD	Annual
Purchases of property, plant and equipment	`PaymentsToAcquirePropertyPlantAndEquipment`	$176.74M	USD	Annual
Purchases of property, plant and equipment	`PaymentsToAcquirePropertyPlantAndEquipment`	$141.47M	USD	Annual
Purchases of property, plant and equipment	`PaymentsToAcquirePropertyPlantAndEquipment`	$141.47M	USD	Annual
Purchases of property, plant and equipment	`PaymentsToAcquirePropertyPlantAndEquipment`	$22.67M	USD	Annual
Purchases of property, plant and equipment	`PaymentsToAcquirePropertyPlantAndEquipment`	$22.67M	USD	Annual
Purchases of investments	`PaymentsToAcquireInvestments`	$246.14M	USD	Annual
Purchases of investments	`PaymentsToAcquireInvestments`	$246.14M	USD	Annual
Purchases of investments	`PaymentsToAcquireInvestments`	$720.95M	USD	Annual
Purchases of investments	`PaymentsToAcquireInvestments`	$720.95M	USD	Annual
Purchases of investments	`PaymentsToAcquireInvestments`	$796.26M	USD	Annual
Purchases of investments	`PaymentsToAcquireInvestments`	$796.26M	USD	Annual
Proceeds from sales and maturities of investments	`ProceedsFromSaleMaturityAndCollectionsOfInvestments`	$326.72M	USD	Annual
Proceeds from sales and maturities of investments	`ProceedsFromSaleMaturityAndCollectionsOfInvestments`	$326.72M	USD	Annual
Proceeds from sales and maturities of investments	`ProceedsFromSaleMaturityAndCollectionsOfInvestments`	$442.34M	USD	Annual
Proceeds from sales and maturities of investments	`ProceedsFromSaleMaturityAndCollectionsOfInvestments`	$442.34M	USD	Annual
Proceeds from sales and maturities of investments	`ProceedsFromSaleMaturityAndCollectionsOfInvestments`	$689.63M	USD	Annual
Proceeds from sales and maturities of investments	`ProceedsFromSaleMaturityAndCollectionsOfInvestments`	$689.63M	USD	Annual
Net cash used in investing activities	`NetCashProvidedByUsedInInvestingActivities`	$-96.16M	USD	Annual
Net cash used in investing activities	`NetCashProvidedByUsedInInvestingActivities`	$-96.16M	USD	Annual
Net cash used in investing activities	`NetCashProvidedByUsedInInvestingActivities`	$-420.07M	USD	Annual
Net cash used in investing activities	`NetCashProvidedByUsedInInvestingActivities`	$-420.07M	USD	Annual
Net cash used in investing activities	`NetCashProvidedByUsedInInvestingActivities`	$-129.29M	USD	Annual
Net cash used in investing activities	`NetCashProvidedByUsedInInvestingActivities`	$-129.29M	USD	Annual
Proceeds from the exercises of stock options	`ProceedsFromStockOptionsExercised`	$3.05M	USD	Annual
Proceeds from the exercises of stock options	`ProceedsFromStockOptionsExercised`	$3.05M	USD	Annual
Proceeds from the exercises of stock options	`ProceedsFromStockOptionsExercised`	$2.39M	USD	Annual
Proceeds from the exercises of stock options	`ProceedsFromStockOptionsExercised`	$2.39M	USD	Annual
Proceeds from the exercises of stock options	`ProceedsFromStockOptionsExercised`	$3.98M	USD	Annual
Proceeds from the exercises of stock options	`ProceedsFromStockOptionsExercised`	$3.98M	USD	Annual
Proceeds from the issuance of common stock, net of offering costs	`ProceedsFromIssuanceOfCommonStock`	-	USD	Annual
Proceeds from the issuance of common stock, net of offering costs	`ProceedsFromIssuanceOfCommonStock`	-	USD	Annual
Proceeds from the issuance of common stock, net of offering costs	`ProceedsFromIssuanceOfCommonStock`	$429.26M	USD	Annual
Proceeds from the issuance of common stock, net of offering costs	`ProceedsFromIssuanceOfCommonStock`	$429.26M	USD	Annual
Proceeds from the issuance of common stock, net of offering costs	`ProceedsFromIssuanceOfCommonStock`	$241.39M	USD	Annual
Proceeds from the issuance of common stock, net of offering costs	`ProceedsFromIssuanceOfCommonStock`	$241.39M	USD	Annual
Proceeds from the sale of future royalties	`ProceedsFromSaleOfFutureRoyalties`	$250.00M	USD	Annual
Proceeds from the sale of future royalties	`ProceedsFromSaleOfFutureRoyalties`	$250.00M	USD	Annual
Proceeds from the sale of future royalties	`ProceedsFromSaleOfFutureRoyalties`	$50.00M	USD	Annual
Proceeds from the sale of future royalties	`ProceedsFromSaleOfFutureRoyalties`	$50.00M	USD	Annual
Proceeds from the sale of future royalties	`ProceedsFromSaleOfFutureRoyalties`	-	USD	Annual
Proceeds from the sale of future royalties	`ProceedsFromSaleOfFutureRoyalties`	-	USD	Annual
Proceeds from the issuance of warrants	`ProceedsFromIssuanceOfWarrants`	-	USD	Annual
Proceeds from the issuance of warrants	`ProceedsFromIssuanceOfWarrants`	-	USD	Annual
Proceeds from the issuance of warrants	`ProceedsFromIssuanceOfWarrants`	-	USD	Annual
Proceeds from the issuance of warrants	`ProceedsFromIssuanceOfWarrants`	-	USD	Annual
Proceeds from the issuance of warrants	`ProceedsFromIssuanceOfWarrants`	$25.00M	USD	Point-in-time
Proceeds from the issuance of warrants	`ProceedsFromIssuanceOfWarrants`	$25.00M	USD	Point-in-time
Proceeds from the issuance of warrants	`ProceedsFromIssuanceOfWarrants`	$25.00M	USD	Annual
Proceeds from the issuance of warrants	`ProceedsFromIssuanceOfWarrants`	$25.00M	USD	Annual
Payment of debt issuance costs	`PaymentsOfDebtIssuanceCosts`	-	USD	Annual
Payment of debt issuance costs	`PaymentsOfDebtIssuanceCosts`	-	USD	Annual
Payment of debt issuance costs	`PaymentsOfDebtIssuanceCosts`	$3.13M	USD	Annual
Payment of debt issuance costs	`PaymentsOfDebtIssuanceCosts`	$3.13M	USD	Annual
Payment of debt issuance costs	`PaymentsOfDebtIssuanceCosts`	$5.00M	USD	Annual
Payment of debt issuance costs	`PaymentsOfDebtIssuanceCosts`	$5.00M	USD	Annual
Proceeds from credit facility	`ProceedsFromLongTermLinesOfCredit`	-	USD	Annual
Proceeds from credit facility	`ProceedsFromLongTermLinesOfCredit`	-	USD	Annual
Proceeds from credit facility	`ProceedsFromLongTermLinesOfCredit`	$392.00M	USD	Annual
Proceeds from credit facility	`ProceedsFromLongTermLinesOfCredit`	$392.00M	USD	Annual
Proceeds from credit facility	`ProceedsFromLongTermLinesOfCredit`	-	USD	Annual
Proceeds from credit facility	`ProceedsFromLongTermLinesOfCredit`	-	USD	Annual
Repayments of credit facility	`RepaymentsOfLongTermLinesOfCredit`	-	USD	Annual
Repayments of credit facility	`RepaymentsOfLongTermLinesOfCredit`	-	USD	Annual
Repayments of credit facility	`RepaymentsOfLongTermLinesOfCredit`	-	USD	Annual
Repayments of credit facility	`RepaymentsOfLongTermLinesOfCredit`	-	USD	Annual
Repayments of credit facility	`RepaymentsOfLongTermLinesOfCredit`	$201.62M	USD	Annual
Repayments of credit facility	`RepaymentsOfLongTermLinesOfCredit`	$201.62M	USD	Annual
Proceeds from Visirna credit agreement	`ProceedsFromLinesOfCredit`	-	USD	Annual
Proceeds from Visirna credit agreement	`ProceedsFromLinesOfCredit`	-	USD	Annual
Proceeds from Visirna credit agreement	`ProceedsFromLinesOfCredit`	-	USD	Annual
Proceeds from Visirna credit agreement	`ProceedsFromLinesOfCredit`	-	USD	Annual
Proceeds from Visirna credit agreement	`ProceedsFromLinesOfCredit`	$10.26M	USD	Annual
Proceeds from Visirna credit agreement	`ProceedsFromLinesOfCredit`	$10.26M	USD	Annual
Net cash provided by financing activities	`NetCashProvidedByUsedInFinancingActivities`	$253.05M	USD	Annual
Net cash provided by financing activities	`NetCashProvidedByUsedInFinancingActivities`	$253.05M	USD	Annual
Net cash provided by financing activities	`NetCashProvidedByUsedInFinancingActivities`	$870.52M	USD	Annual
Net cash provided by financing activities	`NetCashProvidedByUsedInFinancingActivities`	$870.52M	USD	Annual
Net cash provided by financing activities	`NetCashProvidedByUsedInFinancingActivities`	$74.01M	USD	Annual
Net cash provided by financing activities	`NetCashProvidedByUsedInFinancingActivities`	$74.01M	USD	Annual
Net increase (decrease) in cash, cash equivalents and restricted cash	`CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseExcludingExchangeRateEffect`	$3.01M	USD	Annual
Net increase (decrease) in cash, cash equivalents and restricted cash	`CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseExcludingExchangeRateEffect`	$3.01M	USD	Annual
Net increase (decrease) in cash, cash equivalents and restricted cash	`CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseExcludingExchangeRateEffect`	$-12.40M	USD	Annual
Net increase (decrease) in cash, cash equivalents and restricted cash	`CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseExcludingExchangeRateEffect`	$-12.40M	USD	Annual
Net increase (decrease) in cash, cash equivalents and restricted cash	`CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseExcludingExchangeRateEffect`	$124.26M	USD	Annual
Net increase (decrease) in cash, cash equivalents and restricted cash	`CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseExcludingExchangeRateEffect`	$124.26M	USD	Annual
Effect of exchange rate on cash, cash equivalents and restricted cash	`EffectOfExchangeRateOnCashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents`	$-122.00K	USD	Annual
Effect of exchange rate on cash, cash equivalents and restricted cash	`EffectOfExchangeRateOnCashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents`	$-122.00K	USD	Annual
Effect of exchange rate on cash, cash equivalents and restricted cash	`EffectOfExchangeRateOnCashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents`	$4.20M	USD	Annual
Effect of exchange rate on cash, cash equivalents and restricted cash	`EffectOfExchangeRateOnCashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents`	$4.20M	USD	Annual
Effect of exchange rate on cash, cash equivalents and restricted cash	`EffectOfExchangeRateOnCashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents`	$-401.00K	USD	Annual
Effect of exchange rate on cash, cash equivalents and restricted cash	`EffectOfExchangeRateOnCashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents`	$-401.00K	USD	Annual
BEGINNING OF PERIOD	`CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents`	$108.00M	USD	Point-in-time
BEGINNING OF PERIOD	`CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents`	$108.00M	USD	Point-in-time
BEGINNING OF PERIOD	`CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents`	$110.89M	USD	Point-in-time
BEGINNING OF PERIOD	`CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents`	$110.89M	USD	Point-in-time
BEGINNING OF PERIOD	`CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents`	$102.69M	USD	Point-in-time
BEGINNING OF PERIOD	`CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents`	$102.69M	USD	Point-in-time
BEGINNING OF PERIOD	`CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents`	$226.55M	USD	Point-in-time
BEGINNING OF PERIOD	`CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents`	$226.55M	USD	Point-in-time
END OF PERIOD	`CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents`	$108.00M	USD	Point-in-time
END OF PERIOD	`CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents`	$108.00M	USD	Point-in-time
END OF PERIOD	`CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents`	$110.89M	USD	Point-in-time
END OF PERIOD	`CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents`	$110.89M	USD	Point-in-time
END OF PERIOD	`CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents`	$102.69M	USD	Point-in-time
END OF PERIOD	`CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents`	$102.69M	USD	Point-in-time
END OF PERIOD	`CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents`	$226.55M	USD	Point-in-time
END OF PERIOD	`CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents`	$226.55M	USD	Point-in-time
Interest paid	`InterestPaidNet`	-	USD	Annual
Interest paid	`InterestPaidNet`	-	USD	Annual
Interest paid	`InterestPaidNet`	-	USD	Annual
Interest paid	`InterestPaidNet`	-	USD	Annual
Interest paid	`InterestPaidNet`	$19.00K	USD	Annual
Interest paid	`InterestPaidNet`	$19.00K	USD	Annual
Income taxes (refund) paid	`IncomeTaxesPaidNet`	-	USD	Annual
Income taxes (refund) paid	`IncomeTaxesPaidNet`	-	USD	Annual
Income taxes (refund) paid	`IncomeTaxesPaidNet`	$-3.74M	USD	Annual
Income taxes (refund) paid	`IncomeTaxesPaidNet`	$-3.74M	USD	Annual
Income taxes (refund) paid	`IncomeTaxesPaidNet`	$814.00K	USD	Annual
Income taxes (refund) paid	`IncomeTaxesPaidNet`	$814.00K	USD	Annual
Treasury stock received to settle accounts receivable	`TreasuryStockReceivedInExchangeForSettlementOfAccountsReceivable`	-	USD	Annual
Treasury stock received to settle accounts receivable	`TreasuryStockReceivedInExchangeForSettlementOfAccountsReceivable`	-	USD	Annual
Treasury stock received to settle accounts receivable	`TreasuryStockReceivedInExchangeForSettlementOfAccountsReceivable`	-	USD	Annual
Treasury stock received to settle accounts receivable	`TreasuryStockReceivedInExchangeForSettlementOfAccountsReceivable`	-	USD	Annual
Treasury stock received to settle accounts receivable	`TreasuryStockReceivedInExchangeForSettlementOfAccountsReceivable`	$50.00M	USD	Annual
Treasury stock received to settle accounts receivable	`TreasuryStockReceivedInExchangeForSettlementOfAccountsReceivable`	$50.00M	USD	Annual
Capital expenditures included in accrued expenses	`CapitalExpendituresIncurredButNotYetPaid`	$14.04M	USD	Annual
Capital expenditures included in accrued expenses	`CapitalExpendituresIncurredButNotYetPaid`	$14.04M	USD	Annual
Capital expenditures included in accrued expenses	`CapitalExpendituresIncurredButNotYetPaid`	$4.21M	USD	Annual
Capital expenditures included in accrued expenses	`CapitalExpendituresIncurredButNotYetPaid`	$4.21M	USD	Annual
Capital expenditures included in accrued expenses	`CapitalExpendituresIncurredButNotYetPaid`	$277.00K	USD	Annual
Capital expenditures included in accrued expenses	`CapitalExpendituresIncurredButNotYetPaid`	$277.00K	USD	Annual

Stockholders Equity 78 line items

Line Item	Tag	Value	Unit	Period
Common stock, beginning balance (in shares)	`CommonStockSharesOutstanding`	124.38M	shares	Point-in-time
Common stock, beginning balance (in shares)	`CommonStockSharesOutstanding`	124.38M	shares	Point-in-time
Common stock, beginning balance (in shares)	`CommonStockSharesOutstanding`	135.70M	shares	Point-in-time
Common stock, beginning balance (in shares)	`CommonStockSharesOutstanding`	135.70M	shares	Point-in-time
Beginning balance	`StockholdersEquityIncludingPortionAttributableToNoncontrollingInterest`	$418.34M	USD	Point-in-time
Beginning balance	`StockholdersEquityIncludingPortionAttributableToNoncontrollingInterest`	$418.34M	USD	Point-in-time
Beginning balance	`StockholdersEquityIncludingPortionAttributableToNoncontrollingInterest`	$287.16M	USD	Point-in-time
Beginning balance	`StockholdersEquityIncludingPortionAttributableToNoncontrollingInterest`	$287.16M	USD	Point-in-time
Beginning balance	`StockholdersEquityIncludingPortionAttributableToNoncontrollingInterest`	$191.06M	USD	Point-in-time
Beginning balance	`StockholdersEquityIncludingPortionAttributableToNoncontrollingInterest`	$191.06M	USD	Point-in-time
Beginning balance	`StockholdersEquityIncludingPortionAttributableToNoncontrollingInterest`	$503.42M	USD	Point-in-time
Beginning balance	`StockholdersEquityIncludingPortionAttributableToNoncontrollingInterest`	$503.42M	USD	Point-in-time
Treasury stock, beginning balance (in shares)	`TreasuryStockCommonShares`	0.00	shares	Point-in-time
Treasury stock, beginning balance (in shares)	`TreasuryStockCommonShares`	0.00	shares	Point-in-time
Treasury stock, beginning balance (in shares)	`TreasuryStockCommonShares`	2.66M	shares	Point-in-time
Treasury stock, beginning balance (in shares)	`TreasuryStockCommonShares`	2.66M	shares	Point-in-time
Stock-based compensation	`AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue`	$78.13M	USD	Annual
Stock-based compensation	`AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue`	$78.13M	USD	Annual
Stock-based compensation	`AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue`	$73.97M	USD	Annual
Stock-based compensation	`AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue`	$73.97M	USD	Annual
Stock-based compensation	`AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue`	$63.37M	USD	Annual
Stock-based compensation	`AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue`	$63.37M	USD	Annual
Exercise of stock options (in shares)	`StockIssuedDuringPeriodSharesStockOptionsExercised`	535,140.00	shares	Annual
Exercise of stock options (in shares)	`StockIssuedDuringPeriodSharesStockOptionsExercised`	535,140.00	shares	Annual
Exercise of stock options	`StockIssuedDuringPeriodValueStockOptionsExercised`	$3.05M	USD	Annual
Exercise of stock options	`StockIssuedDuringPeriodValueStockOptionsExercised`	$3.05M	USD	Annual
Exercise of stock options	`StockIssuedDuringPeriodValueStockOptionsExercised`	$2.39M	USD	Annual
Exercise of stock options	`StockIssuedDuringPeriodValueStockOptionsExercised`	$2.39M	USD	Annual
Exercise of stock options	`StockIssuedDuringPeriodValueStockOptionsExercised`	$3.98M	USD	Annual
Exercise of stock options	`StockIssuedDuringPeriodValueStockOptionsExercised`	$3.98M	USD	Annual
Common stock - restricted stock units vesting	`StockIssuedDuringPeriodValueRestrictedStockAwardGross`	-	USD	Annual
Common stock - restricted stock units vesting	`StockIssuedDuringPeriodValueRestrictedStockAwardGross`	-	USD	Annual
Common stock - restricted stock units vesting	`StockIssuedDuringPeriodValueRestrictedStockAwardGross`	-	USD	Annual
Common stock - restricted stock units vesting	`StockIssuedDuringPeriodValueRestrictedStockAwardGross`	-	USD	Annual
Common stock - restricted stock units vesting	`StockIssuedDuringPeriodValueRestrictedStockAwardGross`	$2.00K	USD	Annual
Common stock - restricted stock units vesting	`StockIssuedDuringPeriodValueRestrictedStockAwardGross`	$2.00K	USD	Annual
Common stock issued	`StockIssuedDuringPeriodValueNewIssues`	$429.26M	USD	Annual
Common stock issued	`StockIssuedDuringPeriodValueNewIssues`	$429.26M	USD	Annual
Common stock issued	`StockIssuedDuringPeriodValueNewIssues`	$241.39M	USD	Annual
Common stock issued	`StockIssuedDuringPeriodValueNewIssues`	$241.39M	USD	Annual
Common stock - repurchase	`TreasuryStockValueAcquiredCostMethod`	$53.19M	USD	Annual
Common stock - repurchase	`TreasuryStockValueAcquiredCostMethod`	$53.19M	USD	Annual
Issuance of pre-funded warrants	`AdjustmentsToAdditionalPaidInCapitalWarrantIssued`	$25.00M	USD	Annual
Issuance of pre-funded warrants	`AdjustmentsToAdditionalPaidInCapitalWarrantIssued`	$25.00M	USD	Annual
Unrealized gains (losses) on available-for-sale securities	`OtherComprehensiveIncomeLossAvailableForSaleSecuritiesAdjustmentNetOfTax`	$-2.96M	USD	Annual
Unrealized gains (losses) on available-for-sale securities	`OtherComprehensiveIncomeLossAvailableForSaleSecuritiesAdjustmentNetOfTax`	$-2.96M	USD	Annual
Unrealized gains (losses) on available-for-sale securities	`OtherComprehensiveIncomeLossAvailableForSaleSecuritiesAdjustmentNetOfTax`	$3.77M	USD	Annual
Unrealized gains (losses) on available-for-sale securities	`OtherComprehensiveIncomeLossAvailableForSaleSecuritiesAdjustmentNetOfTax`	$3.77M	USD	Annual
Unrealized gains (losses) on available-for-sale securities	`OtherComprehensiveIncomeLossAvailableForSaleSecuritiesAdjustmentNetOfTax`	$2.12M	USD	Annual
Unrealized gains (losses) on available-for-sale securities	`OtherComprehensiveIncomeLossAvailableForSaleSecuritiesAdjustmentNetOfTax`	$2.12M	USD	Annual
Foreign currency translation adjustments	`OtherComprehensiveIncomeLossForeignCurrencyTransactionAndTranslationAdjustmentNetOfTax`	$-122.00K	USD	Annual
Foreign currency translation adjustments	`OtherComprehensiveIncomeLossForeignCurrencyTransactionAndTranslationAdjustmentNetOfTax`	$-122.00K	USD	Annual
Foreign currency translation adjustments	`OtherComprehensiveIncomeLossForeignCurrencyTransactionAndTranslationAdjustmentNetOfTax`	$4.20M	USD	Annual
Foreign currency translation adjustments	`OtherComprehensiveIncomeLossForeignCurrencyTransactionAndTranslationAdjustmentNetOfTax`	$4.20M	USD	Annual
Foreign currency translation adjustments	`OtherComprehensiveIncomeLossForeignCurrencyTransactionAndTranslationAdjustmentNetOfTax`	$-432.00K	USD	Annual
Foreign currency translation adjustments	`OtherComprehensiveIncomeLossForeignCurrencyTransactionAndTranslationAdjustmentNetOfTax`	$-432.00K	USD	Annual
Net (loss) income	`ProfitLoss`	$-209.28M	USD	Annual
Net (loss) income	`ProfitLoss`	$-209.28M	USD	Annual
Net (loss) income	`ProfitLoss`	$-609.69M	USD	Annual
Net (loss) income	`ProfitLoss`	$-609.69M	USD	Annual
Net (loss) income	`ProfitLoss`	$30.11M	USD	Annual
Net (loss) income	`ProfitLoss`	$30.11M	USD	Annual
Common stock, ending balance (in shares)	`CommonStockSharesOutstanding`	124.38M	shares	Point-in-time
Common stock, ending balance (in shares)	`CommonStockSharesOutstanding`	124.38M	shares	Point-in-time
Common stock, ending balance (in shares)	`CommonStockSharesOutstanding`	135.70M	shares	Point-in-time
Common stock, ending balance (in shares)	`CommonStockSharesOutstanding`	135.70M	shares	Point-in-time
Ending balance	`StockholdersEquityIncludingPortionAttributableToNoncontrollingInterest`	$418.34M	USD	Point-in-time
Ending balance	`StockholdersEquityIncludingPortionAttributableToNoncontrollingInterest`	$418.34M	USD	Point-in-time
Ending balance	`StockholdersEquityIncludingPortionAttributableToNoncontrollingInterest`	$287.16M	USD	Point-in-time
Ending balance	`StockholdersEquityIncludingPortionAttributableToNoncontrollingInterest`	$287.16M	USD	Point-in-time
Ending balance	`StockholdersEquityIncludingPortionAttributableToNoncontrollingInterest`	$191.06M	USD	Point-in-time
Ending balance	`StockholdersEquityIncludingPortionAttributableToNoncontrollingInterest`	$191.06M	USD	Point-in-time
Ending balance	`StockholdersEquityIncludingPortionAttributableToNoncontrollingInterest`	$503.42M	USD	Point-in-time
Ending balance	`StockholdersEquityIncludingPortionAttributableToNoncontrollingInterest`	$503.42M	USD	Point-in-time
Treasury stock, ending balance (in shares)	`TreasuryStockCommonShares`	0.00	shares	Point-in-time
Treasury stock, ending balance (in shares)	`TreasuryStockCommonShares`	0.00	shares	Point-in-time
Treasury stock, ending balance (in shares)	`TreasuryStockCommonShares`	2.66M	shares	Point-in-time
Treasury stock, ending balance (in shares)	`TreasuryStockCommonShares`	2.66M	shares	Point-in-time

Data is extracted from SEC EDGAR XBRL filings. Values shown are as reported in the filing.